Edoxaban in elderly patient with morbid obesity and atrial fibrillation: the role of plasma levels evaluation for selecting the appropriate dose

https://doi.org/10.4081/monaldi.2020.1224

Authors

  • Vincenzo Russo | v.p.russo@libero.it Cardiology Unit, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy.
  • Anna Rago Cardiology Unit, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy.
  • Nunzia Laezza Cardiology Unit, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy.
  • Pierpaolo Di Micco Division of Internal Medicine, Buonconsiglio Fatebenefratelli Hospital, Naples, Italy.
  • Laura Giannetti Cardiology Unit, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy.
  • Luigi Atripaldi Chemical Biochemistry Unit, Monaldi Hospital, Naples, Italy.
  • Antonio D'Onofrio Division of Cardiology, Monaldi Hospital, Naples, Italy.
  • Paolo Golino Cardiology Unit, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy.
  • Gerardo Nigro Cardiology Unit, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy.

Abstract

We present the case of a 80-year-old man with atrial fibrillation, morbid obesity (weight 123 kg, height 167 cm, BMI 44.1), high clearance of creatinine and pharmacological polytherapy, in which the serial determinations of edoxaban plasma levels help us to choose the appropriate dose.

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Published
2020-03-20
Info
Issue
Section
Cardiology - Case Reports
Keywords:
atrial fibrillation, obesity, non-vitamin k oral anticoagulant, plasma levels, edoxaban, elderly
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  • PDF: 417
How to Cite
Russo, Vincenzo, Anna Rago, Nunzia Laezza, Pierpaolo Di Micco, Laura Giannetti, Luigi Atripaldi, Antonio D’Onofrio, Paolo Golino, and Gerardo Nigro. 2020. “Edoxaban in Elderly Patient With Morbid Obesity and Atrial Fibrillation: The Role of Plasma Levels Evaluation for Selecting the Appropriate Dose”. Monaldi Archives for Chest Disease 90 (1). https://doi.org/10.4081/monaldi.2020.1224.