Clinical and epidemiological profile of Indian COVID-19 patients from Jaipur: a descriptive study

https://doi.org/10.4081/monaldi.2021.1377

Authors

  • Sunil Mahavar Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India. https://orcid.org/0000-0002-5654-6825
  • Princy Tyagi Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India. https://orcid.org/0000-0002-0691-2479
  • Abhishek Agrawal | drabhie@gmail.com Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India. https://orcid.org/0000-0003-2820-0728
  • Sudhir Bhandari Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India.
  • Subrata Banerjee Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India.
  • Raman Sharma Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India.
  • Prakash Keshwani Department of Medicine, Sawai ManSingh Medical College & Hospital, Jaipur, India.

Abstract

We analyzed the data of 102 confirmed patients with novel Coronavirus 2 infection (COVID-19) during the early period of nationwide lockdown announced in India after the declaration of pandemic. We analyzed epidemiological, clinical characteristics and outcome of hospitalization in 102 patients with positive results for novel corona virus (SARS-CoV-2) RNA testing which were traced on the basis of history of travel, contact with a confirmed COVID-19 case, resident of hotspot areas or presence of symptoms, thus providing an accurate estimate of the proportion of asymptomatic cases in the initial population. Of 102 patients enrolled in the study, 83.3% (85/102) were asymptomatic and 16.67% (17/102) were symptomatic. Seventy-seven (75.49%) were males and 24.50% (25/102) were females. Eighteen (17.6%) patients had associated comorbidities, the most prevalent of which were diabetes mellitus 10.8% (11/102), hypertension 7.8% (8/102), chronic obstructive pulmonary disease (COPD) in 3.92% (4/102), chronic kidney Disease (CKD) 0.98% (1/102), coronary artery Disease (CAD) 0.98% (1/102) and cerebro-vascular disease (CVD) 0.98% (1/102). The clinical spectrum among symptomatic COVID-19 patients varied from dry cough and fever to respiratory failure and multi-organ failure. Twelve (11.76%) patients were kept in intensive care unit (ICU). Ninety-nine (97.05%) patients recovered while three (2.94%) died during hospital stay. With majority of COVID-19 cases in India being asymptomatic, changes in biochemical and inflammatory profile were small and insignificant in asymptomatic patients when compared to symptomatic patients. Elevated NLR, lymphopenia, age and presence of comorbidities were associated with increased severity and poor outcome.

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Published
2021-07-21
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Section
Pneumology - Original Articles
Keywords:
COVID-19, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), asymptomatic, clinical characteristic, India
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How to Cite
Mahavar, Sunil, Princy Tyagi, Abhishek Agrawal, Sudhir Bhandari, Subrata Banerjee, Raman Sharma, and Prakash Keshwani. 2021. “Clinical and Epidemiological Profile of Indian COVID-19 Patients from Jaipur: A Descriptive Study”. Monaldi Archives for Chest Disease 91 (2). https://doi.org/10.4081/monaldi.2021.1377.