Pulmonary fibrosis presenting as an early manifestation of microscopic polyangiitis

https://doi.org/10.4081/monaldi.2012.149

Authors

  • D. Eleftheriou Department of Pneumonology, Army General Hospital of Athens, Athens, Greece.
  • S. Katsenos | skatsenos@yahoo.gr Department of Pneumonology, Army General Hospital of Athens, Athens, Greece.
  • S. Zorbas Department of Nephrology, Army General Hospital of Athens, Athens, Greece.
  • I. Griveas Department of Nephrology, Army General Hospital of Athens, Athens, Greece.
  • K. Psathakis Department of Pneumonology, Army General Hospital of Athens, Athens, Greece.

Abstract

Microscopic polyangiitis (MPA) is a systemic small vessel vasculitis that is included in the pulmonary-renal syndromes. Although glomerulonephritis represents the major clinical feature of MPA indicative of renal involvement, diffuse alveolar haemorrhage is the classic manifestation of pulmonary involvement. However, pulmonary fibrosis is a less frequently reported pulmonary manifestation. Herein we describe a patient who was diagnosed with MPA presenting with radiographic evidence of pulmonary interstitial fibrosis as an early clinical manifestation accompanied by constitutional symptoms such as fever and weight loss. We also include a short literature review focusing on the association between pulmonary fibrosis and MPA.

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Published
2015-12-03
Info
Issue
Section
Case Reports
Keywords:
Microscopic polyangiitis, Perinuclear antineutrophilic cytoplasmic antibodies, Pulmonary fibrosis
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  • PDF: 315
How to Cite
Eleftheriou, D., S. Katsenos, S. Zorbas, I. Griveas, and K. Psathakis. 2015. “Pulmonary Fibrosis Presenting As an Early Manifestation of Microscopic Polyangiitis”. Monaldi Archives for Chest Disease 77 (3-4). https://doi.org/10.4081/monaldi.2012.149.

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