Spontaneous synchronous bilateral hemothorax as the only finding in primary pleural angiosarcoma: a case report and a literature review

  • Guido Levi | guido.levi@yahoo.it Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy. https://orcid.org/0000-0002-7163-2270
  • Nicla Orzes Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy.
  • Silvia Uccelli Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy.
  • Francesca Cettolo Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy.
  • Marianna Arici Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy.
  • Manuela Ciarfaglia Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy.
  • Simona Fisogni Department of Molecular and Translational Medicine. University of Brescia and Pathology Unit, ASST Spedali Civili di Brescia, Italy.
  • Giampietro Marchetti Department of Pneumology, ASST Spedali Civili di Brescia, Italy. https://orcid.org/0000-0002-0753-5572
  • Chiara Rocchetti Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy.

Abstract

Angiosarcoma is a rare malignancy of vascular origin, mostly originating from skin, soft tissues, and breast, but rarely also from the pleura. We present the case of a 55-year-old man who referred to our hospital for a spontaneous bilateral hemothorax. The CT angiography did not show any source of active bleeding; plus, no pleural or lung masses were observable. Cytological and microbiological analyses made on a sample of pleural fluid resulted negative. Despite numerous blood transfusions and thoracenteses, the patient deceased from hemorrhagic shock ten days later and the diagnosis of primary pleural epithelioid angiosarcoma was obtained only by autopsy. Additionally, we present a review of the literature about primary pleural angiosarcomas.

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Published
2021-01-25
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Issue
Section
Pneumology - Case Reports
Keywords:
Pleural angiosarcoma, hemothorax, thoracic oncology, pleural cancer, pleura
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How to Cite
Levi, G., Orzes, N., Uccelli, S., Cettolo, F., Arici, M., Ciarfaglia, M., Fisogni, S., Marchetti, G., & Rocchetti, C. (2021). Spontaneous synchronous bilateral hemothorax as the only finding in primary pleural angiosarcoma: a case report and a literature review. Monaldi Archives for Chest Disease, 91(1). https://doi.org/10.4081/monaldi.2021.1520