https://doi.org/10.4081/monaldi.2021.1520
Spontaneous synchronous bilateral hemothorax as the only finding in primary pleural angiosarcoma: a case report and a literature review
Submitted: July 20, 2020
Accepted: November 25, 2020
Published: January 25, 2021
Accepted: November 25, 2020
Abstract Views: 1150
PDF: 638
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Angiosarcoma is a rare malignancy of vascular origin, mostly originating from skin, soft tissues, and breast, but rarely also from the pleura. We present the case of a 55-year-old man who referred to our hospital for a spontaneous bilateral hemothorax. The CT angiography did not show any source of active bleeding; plus, no pleural or lung masses were observable. Cytological and microbiological analyses made on a sample of pleural fluid resulted negative. Despite numerous blood transfusions and thoracenteses, the patient deceased from hemorrhagic shock ten days later and the diagnosis of primary pleural epithelioid angiosarcoma was obtained only by autopsy. Additionally, we present a review of the literature about primary pleural angiosarcomas.
Moriya Y, Sugawara T, Arai M, et al. Bilateral massive bloody pleurisy complicated by angiosarcoma. Intern Med 2007;46:125-8.
Azzakhmam M, Elktaibi A, Reda El Ochi M, et al. Primary epitheloid angiosarcoma of the pleura: an exceptional tumor location. Pan Afr Med J 2019;33:327.
Pleural Hub Facebook Group. Accessed on: July 20, 2020. Available from: https://www.facebook.com/groups/pleural.hub/
Patrini D, Panagiotopoulos N, Pararajasingham J, et al. Etiology and management of spontaneous haemothorax. J Thorac Dis 2015 Mar;7:520-6.
Kubo S, Kobayashi N, Kaneko A et al. Computed tomography imaging-based observation of the aggressive growth of angiosarcoma: a case study. Respirol Case Rep 2019;7:e00479.
Filippiadis DK, Kapetanakis EI, Spiliopoulos S, et al. Bleeding remission with microwave ablation in a transfusion-dependent patient with hemorrhaging angiosarcoma of the pleura. J Vasc Interv Radiol 2018;29:1298-300.
Durani U, Gallo de Moraes A, Beachey J, et al. Epithelioid angiosarcoma: A rare cause of pericarditis and pleural effusion. Respir Med Case Rep 2018;24:77-80.
Cabibi D, Pipitone G, Porcasi R, et al. Pleural epithelioid angiosarcoma with lymphatic differentiation arisen after radiometabolic therapy for thyroid carcinoma: immunohistochemical findings and review of the literature. Diagn Pathol 2017;12:60.
Miller R, Mudambi L, Vial MR, et al. Radiation-induced angiosarcoma as a cause of pleural effusion. Am J Respir Crit Care Med 2017;196:e10-1.
Yamaguchi K, Yoshino K, Imafuku K, et al. Case of primary pleural angiosarcoma with malignant seeding along the pleural tap tract. J Dermatol 2017;44:e75-6.
Patel MB, Munzer K, Dougherty M, et al. Pleural myiasis associated with pleural angiosarcoma. Chest 2016;149:e157-60.
Panjwani A, Singh I, Parvataneni N, Talukdar P. Spontaneous hemothorax: primary pleural epithelioid angiosarcoma. Egypt J Intern Med 2016;28:170-3.
Matsuda K, Yamaryo T, Akazawa Y, et al. Primary pleural angiosarcoma associated with pneumoconiosis: An autopsy case. Pathol Int 2015;65:603-7.
Zhang S, Zheng Y, Liu W, Yu X. Primary epithelioid angiosarcoma of the pleura: a case report and review of literature. Int J Clin Exp Pathol 2015;8:2153-8.
Onur ST, Günlüoglu Z, Dalar L, et al. Pleural angiosarcoma: a rare cause of spontaneous haemothorax. J Pak Med Assoc 2013;63:265-7.
Quesada A, Quesada J, Khalil K, et al. Morphoproteomic study of primary pleural angiosarcoma of lymphangioendothelial lineage: a case report. Ann Clin Lab Sci 2013;43:317-22.
Abu-Zaid A, Mohammed S. Primary pleural angiosarcoma in a 63-year-old gentleman. Case Rep Pulmonol.2013;2013:974567.
Chen CY, Wu YC, Chou TY, Yang KY. Pleural angiosarcoma mimicking pleural haematoma. Interact Cardiovasc Thorac Surg 2013;17:886-8..
Tsubouchi K, Yoshioka H, Ishida T. Significant response to gemcitabine monotherapy in primary pleural epithelioid angiosarcoma. J Thorac Oncol 2012;7:942-3.
Lorentziadis M, Sourlas A. Primary de novo angiosarcoma of the pleura. Ann Thorac Surg 2012;93:996-8.
Kao YC, Chow JM, Wang KM, et al. Primary pleural angiosarcoma as a mimicker of mesothelioma: a case report **VS**. Diagn Pathol 2011 30;6:130.
Otsubo S, Tanaka S, Kamiryo Y, et al. A case of primary pleural angiosarcoma metastasing to the bladder. Nihon Hinyokika Gakkai Zasshi 2011;102:686-90.
Miyazaki H, Goto A, Hino R, et al. Pleural cavity angiosarcoma arising in chronic expanding hematoma after pneumonectomy. Hum Pathol 2011;42:1576-9.
Baisi A, Raveglia F, De Simone M, Cioffi U. Primary multifocal angiosarcoma of the pleura. Interact Cardiovasc Thorac Surg 2011;12:1069-70.
Dainese E, Pozzi B, Milani M, et al. Primary pleural epithelioid angiosarcoma. A case report and review of the literature. Pathol Res Pract 2010;206:415-9.
Saitou M, Niitsuma K. A case of pyothorax-associated pleural angiosarcoma diagnosed by autopsy. Kekkaku 2009;84:531-4.
Kurtz JE, Serra S, Duclos B, et al. Diffuse primary angiosarcoma of the pleura: a case report and review of the literature. Sarcoma 2004;8:103-6.
Chen L, Shih HJ, Seguerra E Jr, Lin JH. Pathologic quiz case: a 39-year-old man with diffuse pleural thickening and massive hemothorax. Epithelioid angiosarcoma of pleura. Arch Pathol Lab Med 2004;128:1299-300.
Pramesh CS, Madur BP, Raina S, et al. Angiosarcoma of the pleura. Ann Thorac Cardiovasc Surg 2004;10:187-90.
Kimura M, Ito H, Furuta T, et al. Pyothorax-associated angiosarcoma of the pleura with metastasis to the brain. Pathol Int 2003;53:547-51.
Roh MS, Seo JY, Hong SH. Epithelioid angiosarcoma of the pleura: a case report. J Korean Med Sci 2001;16:792-5.
Zhang PJ, Livolsi VA, Brooks JJ. Malignant epithelioid vascular tumors of the pleura: report of a series and literature review. Hum Pathol 2000;31:29-34.
Alexiou C, Clelland CA, Robinson D, Morgan WE. Primary angiosarcomas of the chest wall and pleura. Eur J Cardiothorac Surg 1998;14:523-6.
How to Cite
Levi, Guido, Nicla Orzes, Silvia Uccelli, Francesca Cettolo, Marianna Arici, Manuela Ciarfaglia, Simona Fisogni, Giampietro Marchetti, and Chiara Rocchetti. 2021. “Spontaneous Synchronous Bilateral Hemothorax As the Only Finding in Primary Pleural Angiosarcoma: A Case Report and a Literature Review”. Monaldi Archives for Chest Disease 91 (1). https://doi.org/10.4081/monaldi.2021.1520.
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