Bleeding events in COVID-19: the other side of the coin?


  • Antonietta Coppola | Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, Naples, Italy.
  • Anna Annunziata Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, Naples, Italy.
  • Maria Rosaria Gioia Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, Naples, Italy.
  • Giuseppe Fiorentino Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, Naples, Italy.


We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the anticoagulant therapy to be stopped until bleeding stabilized, one patient needed interventional radiology and one patient died.



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COVID-19 - Collection of articles on the Coronavirus outbreak
COVID 19, LMWH, ileopsoas bleeding
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How to Cite
Coppola, Antonietta, Anna Annunziata, Maria Rosaria Gioia, and Giuseppe Fiorentino. 2021. “Bleeding Events in COVID-19: The Other Side of the Coin?”. Monaldi Archives for Chest Disease, April.

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