https://doi.org/10.4081/monaldi.2021.1814

Post tuberculosis radiological sequelae in patients treated for pulmonary and pleural tuberculosis at a tertiary center in Pakistan

Vol. 92 No. 1 (2022)
Submitted: March 1, 2021
Accepted: July 13, 2021
Published: August 2, 2021
Post TB sequelae, Pleural, Fibrosis, Pleural thickening, Bronchiectasis
Abstract Views: 2029
PDF: 775
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Authors

Syed Muhammad Zubair
https://orcid.org/0000-0002-5917-246X
Department of Medicine, Section of Pulmonary and Critical Care Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Mariyam Gohar Ali
https://orcid.org/0000-0003-2702-294X
Department of Pulmonary and Critical Care Medicine, Dr. Ziauddin Univeristy Hospital, Karachi, Pakistan.
Muhammad Irfan
muhammad.irfan@aku.edu
https://orcid.org/0000-0002-5796-2548
Department of Medicine, Section of Pulmonary and Critical Care Medicine, Aga Khan University Hospital, Karachi, Pakistan.

Treating tuberculosis (TB) is not the end of the disease because of the wide spectrum of post TB sequelae associated with the disease. There is insufficient data on post TB radiological sequelae. The aim of this study is to evaluate the post TB radiological sequelae on chest x-rays in patients who had completed the treatment for pulmonary and pleural TB at a tertiary care hospital of a high TB burden country. This is a retrospective cross-sectional study conducted on patients treated for pulmonary and pleural TB. Adult patients (18 years or above) with a clinical or microbiological diagnosis of pulmonary or pleural TB were included. Patients were classified on the basis of site of TB into pulmonary and pleural TB. Post-treatment radiological sequelae on chest x-ray were evaluated and divided into three main types i.e. fibrosis, bronchiectasis and pleural thickening. During the study period a total of 321 patients were included with a mean age of 44(SD±19) years. Only 17.13% (n=55) patients had normal chest x-rays at the end of treatment and 82.87% (n=266) patients had post-TB radiological sequelae with fibrosis being the most common followed by pleural thickening. The post TB radiological sequelae were high in patients who had diabetes mellitus (78.94%), AFB smear-positive (90.19%), AFB culture-positive (89.84%), Xpert MTB/Rif positive (88.40%) and with drug-resistant TB (100%). As a clinician, one should be aware of all the post TB sequelae so that early diagnosis and management can be facilitated.

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How to Cite

Zubair, Syed Muhammad, Mariyam Gohar Ali, and Muhammad Irfan. 2021. “Post Tuberculosis Radiological Sequelae in Patients Treated for Pulmonary and Pleural Tuberculosis at a Tertiary Center in Pakistan”. Monaldi Archives for Chest Disease 92 (1). https://doi.org/10.4081/monaldi.2021.1814.
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