https://doi.org/10.4081/monaldi.2021.2098
Left atrial invasion of a lung cancer: a case report
Submitted: September 25, 2021
Accepted: November 2, 2021
Published: December 3, 2021
Accepted: November 2, 2021
Abstract Views: 1198
PDF: 425
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Lung cancer is the leading neoplastic form worldwide for both incidence and mortality and represents the largest contributor to new cancer diagnosis. Cardiac extensions of a pulmonary neoplasm are rare and dramatically under-diagnosed because of the extreme variability of clinical presentation and frequently are expression of an advanced-stage primary lung cancer. The invasion often happens through pulmonary veins in absence of a clear respiratory impairment. Symptoms related to the cardiac involvement as the first presentation of a malignant pulmonary neoplasm are very uncommon and related with poor outcome. Here we present a case of invasion of the left atrium of a pulmonary neoplasm with initial cardiac manifestations and a laboratory finding of hypercalcemia.
Lin MT, Ku SC, Wu MZ, Yu CJ. Intracardiac extension of lung cancer via the pulmonary vein. Thorax 2008;63:1122.
DOI: https://doi.org/10.1136/thx.2007.090373
Weinberg BA, Conces DJ Jr, Waller BF. Cardiac manifestations of noncardiac tumors. Part I: Direct effects. Clin Cardiol 1989;12:289-96.
DOI: https://doi.org/10.1002/clc.4960120512
Stewart AF. Clinical practice. Hypercalcemia associated with cancer. N Engl J Med 2005;352:373-9
DOI: https://doi.org/10.1056/NEJMcp042806
Otero J, Lenihan DJ. The "normothermic" Osborn wave induced by severe hypercalcemia. Tex Heart Inst J 2000;27:316-7.
Cipriano F, Dessoti LU, Rodrigues AJ, et al. Report of a lung carcinoma extended to the left atrium through pulmonary vein. J Thorac Dis 2018;10:E46-E51.
DOI: https://doi.org/10.21037/jtd.2017.12.33
Watanabe N, Kubo K. Images in cardiology: Intra-left atrial invasive mass extended via the pulmonary vein. Heart 2001;85:271.
DOI: https://doi.org/10.1136/heart.85.3.271
Ballo P, Laureano R, Briganti M, et al. Left atrial mass invasion from pulmonary neoplasm extension via the right upper pulmonary vein presenting as ipsilateral stroke. Case Rep Med 2016;2016:7084234.
DOI: https://doi.org/10.1155/2016/7084234
Brandt RR, Rubin J, Reeder GS. Intracardiac extension of a lung tumor causing left ventricular inflow obstruction. J Am Soc Echocardiogr 1995;8:930-3.
DOI: https://doi.org/10.1016/S0894-7317(05)80019-7
Chandra R, Abugroun A, Goldberg A, et al. Small cell lung cancer invading the left atrium with subsequent malignant embolic stroke: A case report and review of literature. Cardiol Res 2019;10:188-92.
DOI: https://doi.org/10.14740/cr752w
Hamilton F, Carroll R, Hamilton W, Salisbury C. The risk of cancer in primary care patients with hypercalcaemia: a cohort study using electronic records. Br J Cancer 2014;111:1410-2.
DOI: https://doi.org/10.1038/bjc.2014.433
Edwards CM, Johnson RW. From good to bad: The opposing effects of PTHrP on tumor growth, dormancy, and metastasis throughout cancer progression. Front Oncol 2021;11:644303.
DOI: https://doi.org/10.3389/fonc.2021.644303
Mirrakhimov AE. Hypercalcemia of malignancy: An update on pathogenesis and management. N Am J Med Sci 2015;7:483-93.
DOI: https://doi.org/10.4103/1947-2714.170600
Htwe KK, Aung TT. Diagnostic challenges of a mass in the left atrium. Cureus 2020;12:e8620.
DOI: https://doi.org/10.7759/cureus.8620
How to Cite
Cacciapuoti, Fulvio, Erica Vetrano, and Federico Cacciapuoti. 2021. “Left Atrial Invasion of a Lung Cancer: A Case Report”. Monaldi Archives for Chest Disease 92 (3). https://doi.org/10.4081/monaldi.2021.2098.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Paolo Ruggeri, Federica Lo Bello, Francesco Nucera, Michele Gaeta, Francesco Monaco, Gaetano Caramori, Giuseppe Girbino, Hereditary hyperhomocysteinemia associated with nephrotic syndrome complicated by artery thrombosis and chronic thromboembolic pulmonary hypertension: A case report , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- Massimiliano Polastri, Lara Pisani, Andrea Dell'Amore, Stefano Nava, Revolving door respiratory patients: A rehabilitative perspective , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- Abhishekl Agarwal, Sakshi Batra, Rajendra Prasad, Anand Verma, Abdul Q. Jilani, Surya Kant, A study on the prevalence of depression and the severity of depression in patients of chronic obstructive pulmonary disease in a semi-urban Indian population , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Sotirios D. Moraitis, Apostolos C. Agrafiotis, Dimitrios Pappas, Chrysovalantis Pothitakis, Maria Stergianni, Ioannis Koukis, Thymic pathology and cardiac myxomas: Coincidence or a closer relationship? , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Roberto F.E. Pedretti, Francesco Fattirolli, Raffaele Griffo, Marco Ambrosetti, Elisabetta Angelino, Silvia Brazzo, Ugo Corrà , Nicolò Dasseni, Pompilio Faggiano, Giuseppe Favretto, Oreste Febo, Marina Ferrari, Francesco Giallauria, Cesare Greco, Manuela Iannucci, Maria Teresa La Rovere, Mario Mallardo, Antonio Mazza, Massimo Piepoli, Carmine Riccio, Simonetta Scalvini, Luigi Tavazzi, Pier Luigi Temporelli, Gian Francesco Mureddu, Cardiac Prevention and Rehabilitation “3.0â€: From acute to chronic phase. Position Paper of the ltalian Association for Cardiovascular Prevention and Rehabilitation (GICR-IACPR) , Monaldi Archives for Chest Disease: Vol. 88 No. 3 (2018)
- G.L. Casoni, C. Gurioli, P.N. Chhajed, M. Chilosi, M. Zompatori, D. Olivieri, V. Poletti, The value of transbronchial lung biopsy using jumbo forceps via rigid bronchoscope in diffuse lung disease , Monaldi Archives for Chest Disease: Vol. 69 No. 2 (2008): Pulmonary series
- Dimitrios Papadopoulos, Panagiotis Misthos, Maria Chorti, Vlasios Skopas, Alexandra Nakou, Napoleon Karagianidis, Achilleas Lioulias, Vasiliki Filaditaki, Unilateral pulmonary hypoplasia in an adult patient , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Amanda R. Jimenez, Arielle Shaeffer Weiss, Anthony C. Campagna, Use of pulmonary function test demographic data to identify high-risk patients for lung cancer screening , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Abhijeet Singh, Rajendra Prasad, Rajiv Garg, Surya Kant, Giridhar B. Hosmane, Abhisek Dubey, Abhisek Agarwal, Ram Kishun Verma, A study to estimate prevalence and risk factors of Obstructive Sleep Apnoea Syndrome in a semi-urban Indian population , Monaldi Archives for Chest Disease: Vol. 87 No. 1 (2017)
- Concezione Tommasino, Cardiovascular risk assessment in the senior population undergoing anesthesia for non-cardiac surgery , Monaldi Archives for Chest Disease: Vol. 87 No. 2 (2017)
You may also start an advanced similarity search for this article.
