Clinical features, management and in-hospital outcome of ST elevation myocardial infarction (STEMI) in young adults under 40 years of age

https://doi.org/10.4081/monaldi.2009.331

Authors

  • Seyed Kianoosh Hosseini | skhoseini@yahoo.com Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Abbas Soleimani Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Abbas Ali Karimi Department of Cardiac Surgery, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Saeed Sadeghian Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Sirous Darabian Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Seyed Hesameddin Abbasi Department of Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Seyed Hossein Ahmadi Department of Cardiac Surgery, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Arezou Zoroufian Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Mehran Mahmoodian Department of Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Ali Abbasi Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands.

Abstract

Objectives: This study was designed to evaluate the demographic and clinical findings and in-hospital management and outcome in patients with an acute ST-segment elevation myocardial infarction (STEMI). Material and methods: By review of the Cardiovascular Tehran Heart Center Registry (CVDTHCR), 2028 patients were found to have the acute STEMI. We compared the patients’ characteristics in 109 (5.4%) subjects ≤40 and 1919 subjects > 40 years old. Results: The young patients had less diabetes, hypertension, dyslipidemia and history of MI or prior revascularization, and were more likely to be male (92.7% vs. 74%), smoker (58.7% vs. 31.7%) and have family history of CVD (50.5% vs. 23.4%). The young patients had higher prevalence of angiographically normal coronary artery (13.7% vs. 0.9%; p<0.001). The young patients were more likely to undergo percutaneous coronary intervention (38.5% vs. 18.6%), whereas coronary artery bypass grafting was more common in the old ones (p<0.001). In-hospital death was markedly different among young and old patients (0.9% and 6.1%, respectively; p<0.01). Conclusion: In STEMI population, the risk profile, clinical findings and severity of coronary disease of the young differ substantially from the elderly counterparts. Young patients with STEMI have a favorable outcome compared with that in older patients.

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Published
2016-01-20
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Section
Original Articles
Keywords:
ST-segment elevation, myocardial infarction, risk factors, young, coronary artery disease
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How to Cite
Kianoosh Hosseini, Seyed, Abbas Soleimani, Abbas Ali Karimi, Saeed Sadeghian, Sirous Darabian, Seyed Hesameddin Abbasi, Seyed Hossein Ahmadi, Arezou Zoroufian, Mehran Mahmoodian, and Ali Abbasi. 2016. “Clinical Features, Management and in-Hospital Outcome of ST Elevation Myocardial Infarction (STEMI) in Young Adults under 40 Years of Age”. Monaldi Archives for Chest Disease 72 (2). https://doi.org/10.4081/monaldi.2009.331.

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