Tako-tsubo cardiomyopathy observed in a patient with sepsis and transient hyperthyroidism

https://doi.org/10.4081/monaldi.2009.341

Authors

  • Filippo M. Sarullo | fsarullo@neomedia.it Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
  • Luigi Americo Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
  • Salvatore Accardo Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
  • Sergio Cicero Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
  • Rossella Schicchi Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
  • Maria Schirò Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
  • Antonio Castello Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.

Abstract

ischemic stroke with residual left hemiparesis, was admitted to our hospital because of dyspnoea with clinical evidence of acute pulmonary edema. She was found to have a sinus tachycardia with ST-elevation in leads D1, aVL and V1-V4 in the electrocardiogram, and akinesis of the left ventricular apex with overall left ventricular systolic function being severely impaired and an ejection fraction of 28% on echocardiography. Orotracheal intubation was performed and mechanical ventilation was immediately started. Emergency cardiac catheterization was performed 2 h after the symptom onset. Coronary angiography showed no significant coronary artery disease. Blood analysis revealed an increase in the creatine kinase MB fraction, a significant positive detection in troponin T, a white blood cell count of 35000 per microliter, C-reactive protein of 59,9 mg/dl, and transient elevation in the concentration of free triiodothyronine, free thyroxine, thyroid globulin antibody, and thyroid peroxidase antibody. The symptoms improved during the next days, and follow-up echocardiography 18 days later showed complete resolution of the left ventricular dysfunction. These data suggest that tako-tsubo cardiomyopathy may be induced in patients with sepsis and transient hyperthyroidism.

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Published
2016-01-21
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Section
Case Reports
Keywords:
Tako-tsubo cardiomyopathy, sepsis, transient hyperthyroidism, ventricular function
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How to Cite
Sarullo, Filippo M., Luigi Americo, Salvatore Accardo, Sergio Cicero, Rossella Schicchi, Maria Schirò, and Antonio Castello. 2016. “Tako-Tsubo Cardiomyopathy Observed in a Patient With Sepsis and Transient Hyperthyroidism”. Monaldi Archives for Chest Disease 72 (1). https://doi.org/10.4081/monaldi.2009.341.

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