Assessment of plasma homocysteine levels in shift healthcare workers

https://doi.org/10.4081/monaldi.2008.432

Authors

  • Alfredo Copertaro | copertaroa@asurzona7.marche.it Servizio del Medico Competente, ASUR - Ancona, Italy.
  • Massimo Bracci Medicina del Lavoro, Dipartimento di Patologia Molecolare e Terapie Innovative, Università Politecnica delle Marche, Torrette di Ancona, Italy.
  • Mariella Barbaresi Servizio del Medico Competente, ASUR - Ancona, Italy.

Abstract

Background. Previous studies have indicated an association between shift work and cardiovascular disease. Increased plasma homocysteine levels has been proposed as a cardiovascular risk factor independent of other conventional risk factors. Aims. Our aim is to verify the usefulness of plasma homocysteine as a screening test to prevent cardiovascular diseases in shift workers. Methods. Thirty rotating shift nurses and 28 daytime nurses have been submitted during 18 months to regular taking of arterial pressure and body weight. Venous blood was drawn to measure glycaemia, triglycerides, plasma cortisol level, HDL cholesterol, blood cell count, alanine-aminotransferase, aspartate- aminotransferasi, γ-GT, and plasma homocysteine. Results. No increase in average plasma homocysteine in rotating shift nurses, nor a higher frequency in hyperomocisteinemia than in daytime workers was found. A significant difference was observed in body weight and systolic blood pressure (p<0.05), which resulted higher in rotating shift workers than in daytime workers. A significant increase was observed in alanine-aminotransferase (ALT) among shift workers (p<0.05). Conclusions. Plasma homocysteine measurement should not be employed as a screening test for the prevention of cardiovascular disease in rotating shift workers.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Downloads

Published
2016-01-26
Info
Issue
Section
Original Articles
Keywords:
cardiovascular diseases, shift work, hyperhomocysteinemia
Statistics
  • Abstract views: 486

  • PDF: 492
How to Cite
Copertaro, Alfredo, Massimo Bracci, and Mariella Barbaresi. 2016. “Assessment of Plasma Homocysteine Levels in Shift Healthcare Workers”. Monaldi Archives for Chest Disease 70 (1). https://doi.org/10.4081/monaldi.2008.432.

Similar Articles

You may also start an advanced similarity search for this article.