Familial Hypercholesterolemia in Cardiac Rehabilitation: a new field of interest

Submitted: August 20, 2015
Accepted: August 20, 2015
Published: August 20, 2015
Abstract Views: 1222
PDF: 1184
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Familial hypercholesterolemia (FH) is a frequently undiagnosed genetic disease characterized by substantial elevations of low-density lipoprotein cholesterol (LDL-C). The prevalence of heterozygous FH (HeFH) in the general population is 1:500 inhabitants, while the prevalence of homozygous FH (HoFH) is 1:1.000.000. If FH is not identified and aggressively treated at an early age, affected individuals have a 20-fold increased lifetime risk of coronary heart disease compared with the general population. This narrative review provide a concise overview of recommendations for diagnosis and treatment of adults and children with FH, and discuss the utility of considering FH as a comorbidity at the entry of Cardiac Rehabilitation programmes.

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Ambrosetti, Marco, Gabriella Malfatto, Anna Maria Cremona, Marcello Arca, and Pompilio Faggiano. 2015. “Familial Hypercholesterolemia in Cardiac Rehabilitation: A New Field of Interest”. Monaldi Archives for Chest Disease 82 (2). https://doi.org/10.4081/monaldi.2014.49.