Familial Hypercholesterolemia in Cardiac Rehabilitation: a new field of interest

https://doi.org/10.4081/monaldi.2014.49

Authors

  • Marco Ambrosetti | m.ambrosetti@clinicaleterrazze.com UO Cardiologia e Angiologia Riabilitativa, Clinica Le Terrazze, Cunardo (VA), Italy.
  • Gabriella Malfatto Cardiologia Riabilitativa, Istituto Auxologico, Milano, Italy.
  • Anna Maria Cremona Degenza Breve Internistica, Ospedale di Circolo, Varese, Italy.
  • Marcello Arca Dipartimento Medicina Interna e Specialità Mediche - Centro Aterosclerosi, Sapienza Università di Roma, Roma, Italy.
  • Pompilio Faggiano UO Cardiologia, Spedali Civili e Università di Brescia, Brescia, Italy.

Abstract

Familial hypercholesterolemia (FH) is a frequently undiagnosed genetic disease characterized by substantial elevations of low-density lipoprotein cholesterol (LDL-C). The prevalence of heterozygous FH (HeFH) in the general population is 1:500 inhabitants, while the prevalence of homozygous FH (HoFH) is 1:1.000.000. If FH is not identified and aggressively treated at an early age, affected individuals have a 20-fold increased lifetime risk of coronary heart disease compared with the general population. This narrative review provide a concise overview of recommendations for diagnosis and treatment of adults and children with FH, and discuss the utility of considering FH as a comorbidity at the entry of Cardiac Rehabilitation programmes.

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Published
2015-08-20
Info
Issue
Section
Reviews
Keywords:
familial hypercholesterolemia, cardiac rehabilitation, prevention
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  • PDF: 901
How to Cite
Ambrosetti, Marco, Gabriella Malfatto, Anna Maria Cremona, Marcello Arca, and Pompilio Faggiano. 2015. “Familial Hypercholesterolemia in Cardiac Rehabilitation: A New Field of Interest”. Monaldi Archives for Chest Disease 82 (2). https://doi.org/10.4081/monaldi.2014.49.

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