Lung and respiratory muscle function at discharge from a respiratory intensive care unit

https://doi.org/10.4081/monaldi.2005.631

Authors

  • M. Vitacca | mvitacca@fsm.it Pulmonary Department and Respiratory Intermediate Intensive Care Unit, S. Maugeri Foundation IRCCS Gussago (BS), Italy.
  • L. Bianchi Pulmonary Department and Respiratory Intermediate Intensive Care Unit, S. Maugeri Foundation IRCCS Gussago (BS), Italy.
  • L. Barbano Pulmonary Department and Respiratory Intermediate Intensive Care Unit, S. Maugeri Foundation IRCCS Gussago (BS), Italy.
  • N. Ambrosino Pulmonary Unit, Cardio-Thoracic Department, University Hospital of Pisa, Italy.

Abstract

Background. The purpose of this prospective observational study was to describe lung and respiratory muscle function at Respiratory Intensive Care Unit (RICU) discharge after a severe exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Methods. The study was conducted in 42 consecutive COPD patients in whom arterial blood gases, dynamic and static lung volumes, maximal inspiratory pressure (MIP) were assessed at discharge from the RICU and compared with values measured 6 months previously when they were in a stable state. The same measurements were performed at 6-month interval in 42 comparable stable COPD patients not requiring any hospitalisation for at least 6 months used as controls. Results. 24% of patients in the study group were discharged with hypercapnia whereas they were normocapnic before the acute episode. Compared to prior to exacerbation, patients of study group showed a significant worsening in mean values of PaCO2 (p=0.005), MIP (p=0.005) and FEV1 (p=0.041). Predefined criteria of worsening in PaCO2, MIP and FEV1 were observed in 47%, 33% and 28% of patients in study respectively. Neither lung nor respiratory muscle function in last stable state did predict post RICU functional worsening. In a period of 6 months controls showed no change in the studied parameters. Conclusions. After a severe acute exacerbation requiring admission to a RICU and immediately before discharge 1) a large proportion of COPD patients still show preserved lung and respiratory muscle function 2) more than one third of them would require further care and rehabilitative attempts to restore functional derangements.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Downloads

Published
2005-09-30
Info
Issue
Section
Original Articles
Keywords:
Acute exacerbations of COPD, respiratory failure, respiratory muscles, lung function
Statistics
  • Abstract views: 311

  • PDF: 227
How to Cite
Vitacca, M., L. Bianchi, L. Barbano, and N. Ambrosino. 2005. “Lung and Respiratory Muscle Function at Discharge from a Respiratory Intensive Care Unit”. Monaldi Archives for Chest Disease 63 (3). https://doi.org/10.4081/monaldi.2005.631.

Most read articles by the same author(s)

1 2 > >> 

Similar Articles

You may also start an advanced similarity search for this article.