Critical review of the equations predicting 6-minute walking distance in obese subjects


  • Lorenzo Maria Donini | Sapienza University of Rome, Italy.
  • Eleonora Poggiogalle Sapienza University of Rome, Italy.
  • Veronica Mosca Sapienza University of Rome, Italy.
  • Alessandro Pinto Sapienza University of Rome, Italy.
  • Silvia Migliaccio University Foro Italico of Rome, Italy.
  • Amelia Brunani Istituto Auxologico Italiano IRCCS, Italy.
  • Paolo Capodaglio Istituto Auxologico Italiano IRCCS, Italy.


The correlation between the 6-minute walking distance and obesity has been only partially explored. Results obtained from the existing predictive equations are influenced by a variety of factors (health status, severity of obesity, reduced muscle strength and mobility, decreased aerobic capacity, presence of comorbidities). The aim of our study was to verify, compare and discuss the 6MWD predictive capacity of the equations currently available in the literature in a sample of obese subjects. Despite similar study design, the considered articles varied with regard to the number of individuals included and to age range. None of the equations available in the literature was able to accurately predict the six-minute walked distance performed by the obese subjects involved in our study. The six-minute walked distance performed by obese subjects seems to be influenced by other factors than the variables included in the equations from the literature, suggesting that they may not thoroughly capture the complexity of disability in obese people. Future research should be designed in order to validate population-specific equations, by including variables related to clinical, functional, and psychological areas, which are usually impaired in obese individuals. 



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Pneumology - Original Articles
Obesity, disability, 6-minute walking test.
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How to Cite
Donini, Lorenzo Maria, Eleonora Poggiogalle, Veronica Mosca, Alessandro Pinto, Silvia Migliaccio, Amelia Brunani, and Paolo Capodaglio. 2016. “Critical Review of the Equations Predicting 6-Minute Walking Distance in Obese Subjects”. Monaldi Archives for Chest Disease 81 (1-2).