A study to estimate prevalence and risk factors of Obstructive Sleep Apnoea Syndrome in a semi-urban Indian population

https://doi.org/10.4081/monaldi.2017.773

Authors

  • Abhijeet Singh King George Medical University, Lucknow, India.
  • Rajendra Prasad | rprasaddirvpci@gmail.com King George Medical University, Lucknow, India.
  • Rajiv Garg King George Medical University, Lucknow, India.
  • Surya Kant King George Medical University, Lucknow, India.
  • Giridhar B. Hosmane King George Medical University, Lucknow, India.
  • Abhisek Dubey King George Medical University, Lucknow, India.
  • Abhisek Agarwal King George Medical University, Lucknow, India.
  • Ram Kishun Verma King George Medical University, Lucknow, India.

Abstract

Obstructive Sleep Apnea Syndrome (OSAS) has been recognised as a major cause of morbidity and mortality in developing countries like India. There is still a paucity of Indian studies regarding the prevalence of OSAS. The current single centre prospective cross-sectional study was undertaken to know prevalence estimates for key symptoms and features that can indicate the presence of OSAS in an Indian population. A survey was conducted on subjects with age groups ≥ 25 years at King George's Medical University, Lucknow, Uttar Pradesh, India from August 2009 to July 2011. Data was recorded during the interview on the basis of Berlin Questionnaire (BQ). Risk factors for OSAS were also evaluated. Risk group categorization for OSAS was done with the help of a questionnaire and overnight polysomnography was performed in each group to measure apnea and hypopnea index (AHI). Out of 1816 subjects, 1512 (response rate 83.3%) finally participated in the survey with mean age 42.6±11.2 years, males 67.9% and females 32.1%. Of them 6.2% were found to be at high-risk OSAS; 12.2% were obese (Body Mass Index ≥30 kg/m2) and 33.5% of the obese population were at high-risk OSAS. Among high-risk patients with OSAS, 62.4% had hypertension. Statistically significant and independent risk factors found for OSAS were obesity, large neck size, alcoholism and use of sedatives/tranquillizers. High-risk category predicted an AHI ≥5 with a sensitivity of 86.3% (95% CI 73.1-93.8), specificity of 93.1% (95% CI 89.1-95.7), positive and negative predictive values of 70.9% (95% CI 57.9-81.4) and 97.2% (95% CI 94.1-98.8) respectively. It can be concluded that BQ questionnaire can still be used as a pre-assessment tool for predicting persons at risk for OSAS in clinical practice. Further studies on estimation of prevalence of OSAS by applying BQ are warranted in near future from other regions of India.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Downloads

Published
2017-05-18
Info
Issue
Section
Pneumology - Original Articles
Supporting Agencies
, , , ,
Keywords:
Obstructive Sleep apnea, Berlin questionnaire, Epworth sleepiness scale score (ESS Score), obesity, hypertension.
Statistics
  • Abstract views: 1237

  • PDF: 578
How to Cite
Singh, Abhijeet, Rajendra Prasad, Rajiv Garg, Surya Kant, Giridhar B. Hosmane, Abhisek Dubey, Abhisek Agarwal, and Ram Kishun Verma. 2017. “A Study to Estimate Prevalence and Risk Factors of Obstructive Sleep Apnoea Syndrome in a Semi-Urban Indian Population”. Monaldi Archives for Chest Disease 87 (1). https://doi.org/10.4081/monaldi.2017.773.