Correlation of aspergillus skin hypersensitivity with the duration and severity of asthma

  • Vishal Chopra | drvishalchopra@hotmail.com Government Medical College, Department of Pulmonary Medicine, India. http://orcid.org/0000-0002-9513-4866
  • Hardik Jain Government Medical College, Department of Pulmonary Medicine, India.
  • Akhil D. Goel All India Institute of Medical Sciences, New Delhi, India.
  • Siddharth Chopra Government Medical College, Department of Pulmonary Medicine, India.
  • Ashrafjit S. Chahal Government Medical College, Department of Pulmonary Medicine, India.
  • Neha Garg Government Medical College, Department of Pulmonary Medicine, India.
  • Vidhu Mittal Government Medical College, Department of Pulmonary Medicine, India.

Abstract

Asthma is a significant health problem worldwide and Allergic Bronchopulmonary aspergillosis (ABPA) complicates the course of 1-2% of patients of asthma. Aspergillus skin hypersensitivity (AH) is the first step for diagnosis of ABPA. This study was conducted to know the correlation of AH with severity and duration of asthma. Patients, age >15 years, of asthma attending this hospital from January 2015 to December 2015 were included. Asthma was diagnosed clinically and confirmed with spirometry. Of 282 patients 206 patients were AH positive. The AST-positivity in patients having severe asthma (96.8%) was higher than that in patients having mild (36.8%) and moderate asthma (80.4%). The median (IQR) duration of asthma of AH positive patients was 5.0 yrs. This study emphasized the need of ABPA screening by intradermal skin test especially in patients having severe asthma and/or those having asthma for longer duration in order for early diagnosis of ABPA.

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Author Biographies

Vishal Chopra, Government Medical College, Department of Pulmonary Medicine
Associate Professor, Department of Chest & TB, Government Medical College, Patiala, Punjab, India
Hardik Jain, Government Medical College, Department of Pulmonary Medicine
Junior Resident, Department of Chest & TB, Government Medical College, Patiala, Punjab, India
Akhil D. Goel, All India Institute of Medical Sciences, New Delhi
Senior Resident,CCM, All India Institute of Medical Sciences, New Delhi
Siddharth Chopra, Government Medical College, Department of Pulmonary Medicine
Intern, Government Medical College, Patiala, Punjab, India
Ashrafjit S. Chahal, Government Medical College, Department of Pulmonary Medicine
Medical Officer Department of Chest & TB, Government Medical College, Patiala, Punjab, India
Vidhu Mittal, Government Medical College, Department of Pulmonary Medicine
Senior Resident, Department of Chest & TB, Government Medical College, Patiala, Punjab, India
Published
2017-09-25
Info
Issue
Section
Pneumology - Original Articles
Keywords:
Aspergillus skin hypersensitivity, asthma, ABPA.
Statistics
  • Abstract views: 657

  • PDF: 280
How to Cite
Chopra, V., Jain, H., Goel, A. D., Chopra, S., Chahal, A. S., Garg, N., & Mittal, V. (2017). Correlation of aspergillus skin hypersensitivity with the duration and severity of asthma. Monaldi Archives for Chest Disease, 87(3). https://doi.org/10.4081/monaldi.2017.826