Kounis syndrome, a disease to know: Case report and review of the literature

https://doi.org/10.4081/monaldi.2018.898

Authors

  • Edoardo Sciatti | edoardo.sc@tin.it University and ASST Spedali Civili, Cardiology Unit, Italy. http://orcid.org/0000-0002-3479-3454
  • Enrico Vizzardi University and ASST Spedali Civili, Cardiology Unit, Italy.
  • Dario S. Cani University and ASST Spedali Civili, Cardiology Unit, Italy.
  • Assunta Castiello University and ASST Spedali Civili, Cardiology Unit, Italy.
  • Ivano Bonadei University and ASST Spedali Civili, Cardiology Unit, Italy.
  • Daria Savoldi University and ASST Spedali Civili, Cardiology Unit, Italy.
  • Marco Metra University and ASST Spedali Civili, Cardiology Unit, Italy.
  • Antonio D'Aloia University and ASST Spedali Civili, Cardiology Unit, Italy.

Abstract

The case deals with an anaphylactoid reaction to intravenous ampicillin/sulbactam resulting in cardiogenic syncope and myocardial damage. Symptoms and ECG modifications promptly disappeared after corticosteroids administration. The Kounis syndrome is an acute coronary syndrome, including coronary spasm, acute myocardial infarction and stent thrombosis, resulting from an anaphylactic or anaphylactoid or allergic or hypersensitivity insult. First described in 1991, it can be caused by a lot of substances, particularly antibiotics. The management should be directed to both the allergic reaction and the myocardial damage. The Kounis syndrome is a not rare disease that every physician should know because of the wideness of triggers and the possible fatal evolution if not promptly recognized.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Downloads

Published
2018-03-16
Info
Issue
Section
Cardiology - Case Reports
Keywords:
Kounis syndrome, anaphylactoid reaction, ampicillin/sulbactam, coronary artery, acute coronary syndrome.
Statistics
  • Abstract views: 1803

  • PDF: 843
How to Cite
Sciatti, Edoardo, Enrico Vizzardi, Dario S. Cani, Assunta Castiello, Ivano Bonadei, Daria Savoldi, Marco Metra, and Antonio D’Aloia. 2018. “Kounis Syndrome, a Disease to Know: Case Report and Review of the Literature”. Monaldi Archives for Chest Disease 88 (1). https://doi.org/10.4081/monaldi.2018.898.

Most read articles by the same author(s)

1 2 > >>