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Occurrence of thymic pathology in two families. Is familial screening justified?

Sotirios D. Moraitis, Apostolos C. Agrafiotis, Amalia Kapranou, Marina Constantinou, Konstantinos Kanakakis, Panagiotis Hountis
  • Sotirios D. Moraitis
    Athens Naval and Veterans Hospital, Department of Thoracic Surgery, Greece
  • Amalia Kapranou
    Athens Naval and Veterans Hospital, Department of Pathology, Greece
  • Marina Constantinou
    Athens Naval and Veterans Hospital, Department of Pathology, Greece
  • Konstantinos Kanakakis
    Athens Naval and Veterans Hospital, Department of Thoracic Surgery, Greece
  • Panagiotis Hountis
    Athens Naval and Veterans Hospital, Department of Thoracic Surgery, Greece

Abstract

The familial occurrence of thymic pathology, even though rare, is widely reported in the literature and mainly concerns cases of familial autoimmune myasthenia gravis. Other less frequent cases of familial occurrence of thymoma, thymic carcinoid and thymic hyperplasia have been described. It seems that the familial occurrence is poorly recorded and thus its prevalence is underestimated. We report two families whose members presented different forms of thymic pathology and discuss the necessity of screening programs in family members of patients presenting a thymic lesion.

Keywords

Familial; thymoma; thymic carcinoma; thymic hyperplasia.

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Submitted: 2018-02-03 00:31:43
Published: 2018-09-04 16:04:33
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Copyright (c) 2018 Sotirios D. Moraitis, Apostolos C. Agrafiotis, Amalia Kapranou, Marina Constantinou, Konstantinos Kanakakis, Panagiotis Hountis

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