@article{Compare_Proietti_Del Forno_Vitelli_Grieco_Maresca_Giallauria_2015, title={Vulnerable personality and Takotsubo cardiomyopathy consequent to emotional stressful events: a clinical case report}, volume={76}, url={https://www.monaldi-archives.org/macd/article/view/197}, DOI={10.4081/monaldi.2011.197}, abstractNote={Introduction: Although the onset of Takotsubo cardiomyopathy (TTC) can be triggered by an acute, intense emotional stress, the exact pathogenic mechanisms still remain undefined. Presentation: A 58-year-old female was sent by ambulance to the Emergency Department (ED) for chest pain and ST elevations on ECG. Her chest pain began 3 hours before on admission after a domestic argument. Transthoracic echocardiogram showed severe systolic dysfunction with an ejection fraction of 20%. Cardiac catheterization revealed no significant coronary artery disease. The left ventriculogram showed apical ballooning with hyperdynamic proximal segments. A diagnosis of Takotsubo Cardiomyophaty (TTC) was made according to the Mayo Clinic 2008 criteria. The patient evolved with improvement of her condition and, therefore, was discharged from the hospital. Follow-up echocardiogram seven days later showed normal LV size and function with ejection fraction (EF) of 43%. Paykel Life Stress Event Scale identified as emotional trigger a domestic argument occurred 3 hours before symptom onset. History showed a major life stress event, death of a loved one, six months before symptoms. The patient underwent psychological assessment after hospital discharge by Emotional Regulation Questionnaire and BDI showing high suppression/ low reappraisal profile and moderate depression. Conclusion: This case highlights the hypothesis of a possible link between cognitive emotional processing and vulnerability to Takotsubo syndrome.}, number={2}, journal={Monaldi Archives for Chest Disease}, author={Compare, Angelo and Proietti, Riccardo and Del Forno, Domenico and Vitelli, Alessandra and Grieco, Alessandra and Maresca, Luigi and Giallauria, Francesco}, year={2015}, month={Dec.} }