@article{Violini_Cifarelli_De Felice_Chin_2017, title={Treatment of mitral regurgitation}, volume={87}, url={https://www.monaldi-archives.org/macd/article/view/854}, DOI={10.4081/monaldi.2017.854}, abstractNote={<p class="Default">In the elderly mitral regurgitation is very frequent and surgical correction of mitral regurgitation (MR) has often a high operative risk, consequently, over the years, different percutaneous transcatheter techniques have been developed as a valid alternative to surgery. The edge-to-edge repair with the MitraClip device has gained a wide clinical application, supported by several studies, both randomize trials and registries. It is indicated in functional MR as in degenerative MR. The outcome is usually positive, resulting in a reduction of the regurgitation to grade 1+ or 2+ and an improvement in the functional class to I or II reducing hospitalizations. Its cost-effectiveness too is supported by some studies.<strong></strong></p>}, number={2}, journal={Monaldi Archives for Chest Disease}, author={Violini, Roberto and Cifarelli, Alberta and De Felice, Francesco and Chin, Diana}, year={2017}, month={Jul.} }