TY - JOUR AU - Cipolla, Gaia AU - Relo, Rosalba AU - Pasciuta, Elisa AU - Catalano, Domenica AU - Lo Bello, Federica AU - Coppolino, Irene AU - Ruggeri, Paolo AU - Proietto, Alfio AU - Buccafusca, Maria AU - Cutroneo, Paola Maria AU - Trifirò, Gianluca AU - Caramori, Gaetano PY - 2020/07/24 Y2 - 2024/03/28 TI - A case of lung injury resembling diffuse pulmonary hemorrhage after the first administration of alemtuzumab in a patient with multiple sclerosis. Role of the HRCT JF - Monaldi Archives for Chest Disease JA - Monaldi Arch Chest Dis VL - 90 IS - 3 SE - Pneumology - Case Reports DO - 10.4081/monaldi.2020.1352 UR - https://www.monaldi-archives.org/macd/article/view/1352 SP - AB - <p>Diffuse alveolar hemorrhage (DAH) is an acute often life-threatening condition characterized by a variable combination of hemoptysis, dyspnoea, diffuse and bilateral ground glass pulmonary opacities, anemia and hypoxemia, that can be induced by different causes, including several drugs. We report here the case of a 25-year-old woman who has been admitted to our pulmonary clinic for the onset of chest pain, cough and haemoptysis, started one week after her first treatment with alemtuzumab for multiple sclerosis. Computed tomography (CT) scan of the chest at the admission showed diffuse and bilateral ground glass pulmonary opacities. Her symptoms resolved completely without any treatment, after the interruption of alemtuzumab, and CT scan of the chest performed one month later showed total disappearance of the pulmonary opacities.</p> ER -