https://doi.org/10.4081/monaldi.2021.1601
Hammering home the sickle: an instructive case of endobronchial anaplastic large cell lymphoma
Submitted: September 7, 2020
Accepted: February 24, 2021
Published: April 8, 2021
Accepted: February 24, 2021
Abstract Views: 850
PDF: 345
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
It is extremely unusual for primary pulmonary lymphoma, an uncommon occurrence in any form, to be of T-cell origin and to manifest as an endobronchial lesion. Each of these characteristics is rare individually, so cases that combine them are exceptional. We report a patient in whom primary pulmonary anaplastic large cell lymphoma, a T-cell neoplasm, presented with obstruction of the left upper lobe bronchus, resulting in left upper lobe atelectasis and creating the radiographic luftsichel sign. We briefly discuss anaplastic large cell lymphoma as a whole, place our case in the context of previously published literature on endobronchial anaplastic large cell lymphoma, and review the genesis of the luftsichel sign.
Pan Z, Xu ML. T-cell and NK-cell lymphomas in the lung. Semin Diagn Pathol 2020;37:273-82.
DOI: https://doi.org/10.1053/j.semdp.2020.04.003
Solomonov A, Zuckerman T, Goralnik L, et al. Non-Hodgkin's lymphoma presenting as an endobronchial tumor: report of eight cases and literature review. Am J Hematol 2008;83:416-9.
DOI: https://doi.org/10.1002/ajh.21112
Kligerman SJ, Franks TJ, Galvin JR. Primary extranodal lymphoma of the thorax. Radiol Clin North Am 2016;54:673-87.
DOI: https://doi.org/10.1016/j.rcl.2016.03.002
L'Hoste RJ Jr, Filippa DA, Lieberman PH, Bretsky S. Primary pulmonary lymphomas. A clinicopathologic analysis of 36 cases. Cancer 1984;54:1397-406.
DOI: https://doi.org/10.1002/1097-0142(19841001)54:7<1397::AID-CNCR2820540728>3.0.CO;2-4
Cadranel J, Wislez M, Antoine M. Primary pulmonary lymphoma. Eur Respir J 2002;20:750-62.
DOI: https://doi.org/10.1183/09031936.02.00404102
Sammassimo S, Pruneri G, Andreola G, et al. A retrospective international study on primary extranodal marginal zone lymphoma of the lung (BALT lymphoma) on behalf of International Extranodal Lymphoma Study Group (IELSG). Hematol Oncol 2016;34:177-83.
DOI: https://doi.org/10.1002/hon.2243
Rush WL, Andriko JA, Taubenberger JK, et al. Primary anaplastic large cell lymphoma of the lung: a clinicopathologic study of five patients. Mod Pathol 2000;13:1285-92.
DOI: https://doi.org/10.1038/modpathol.3880235
Kim DH, Ko YH, Lee MH, Ree HJ. Anaplastic large cell lymphoma presenting as an endobronchial polypoid mass. Respiration 1998;65:156-8.
DOI: https://doi.org/10.1159/000029248
Chand T, Bansal A, Dua H, Sharma K. Endotracheobronchial lymphoma: Two unusual case reports and review of article. Lung India 2016;33:653-6.
DOI: https://doi.org/10.4103/0970-2113.192873
Von Ende E, Kauffman T, Munoz PA, Martinez-Jiménez S. Primary pulmonary anaplastic large cell lymphoma: A rare malignancy and rare cause of the luftsichel sign. Case Rep Radiol 2018;2018:8574642.
DOI: https://doi.org/10.1155/2018/8574642
Carvalho J, Marques DP, Oliveira I, Claudino C. A rare case of primary pulmonary anaplastic large cell lymphoma. Eur J Case Rep Intern Med 2019;6:001249.
DOI: https://doi.org/10.12890/2019_001249
Blankenbaker DG. The luftsichel sign. Radiology 1998;208:319-20.
DOI: https://doi.org/10.1148/radiology.208.2.9680553
Day K, Oliva I. Signs in cardiopulmonary imaging: luftsichel sign. J Thorac Imaging 2015;30:W1.
DOI: https://doi.org/10.1097/RTI.0000000000000151
Eyre TA, Khan D, Hall GW, Collins GP. Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: current and future perspectives in adult and paediatric disease. Eur J Haematol 2014;93:455-68.
DOI: https://doi.org/10.1111/ejh.12360
Leventaki V, Bhattacharyya S, Lim MS. Pathology and genetics of anaplastic large cell lymphoma. Semin Diagn Pathol 2020;37:57-71.
DOI: https://doi.org/10.1053/j.semdp.2019.12.002
Chiarle R, Voena C, Ambrogio C, et al. The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat Rev Cancer 2008;8:11-23.
DOI: https://doi.org/10.1038/nrc2291
Vose J, Armitage J, Weisenburger D, International T-Cell Lymphoma Project. International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes. J Clin Oncol 2008;26:4124-30.
DOI: https://doi.org/10.1200/JCO.2008.16.4558
Horwitz S, O'Connor OA, Pro B, et al. Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial. Lancet 2019;393:229-40. Erratum in: Lancet 2019;393:228.
Gambacorti-Passerini C, Messa C, Pogliani EM. Crizotinib in anaplastic large-cell lymphoma. N Engl J Med 2011;364:775-6
DOI: https://doi.org/10.1056/NEJMc1013224
Gambacorti Passerini C, Farina F, Stasia A, et al. Crizotinib in advanced, chemoresistant anaplastic lymphoma kinase-positive lymphoma patients. J Natl Cancer Inst 2014;106:djt378.
DOI: https://doi.org/10.1093/jnci/djt378
How to Cite
Abu-Hishmeh, Mohammad, Laura Miranda, Fouzia Shakil, Tauseef Ahmed, and Oleg Epelbaum. 2021. “Hammering Home the Sickle: An Instructive Case of Endobronchial Anaplastic Large Cell Lymphoma”. Monaldi Archives for Chest Disease 91 (3). https://doi.org/10.4081/monaldi.2021.1601.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Cuneyt Tetikkurt, Halil Yanardag, Burcak Haluk Sayman, Muammer Bilir, Seza Tetikkurt, Seckin Bilgic, Bahar Kubat, Seyda Bilgin, Diagnostic utility of 68Ga-citrate and 18FDG PET/CT in sarcoidosis patients , Monaldi Archives for Chest Disease: Vol. 90 No. 4 (2020)
- Pier Luigi Temporelli, Giovanni Battista Zito, Roberto Franco Pedretti, Francesco Iachini Belisarii, Giuseppe Putortì, Pompilio Faggiano, Nonsteroid anti-inflammatory drugs (NSAID) and risk of cardiovascular events. Literature review and clinical implications , Monaldi Archives for Chest Disease: Vol. 82 No. 3 (2014): Cardiac series
- Umberto Caterino, Dario Amore , Maria Chiara Petagna, Dino Casazza, Roberto Marchese, Emergency rigid bronchoscopy in two lower social class patients with mirror like complete pulmonary malignant atelectasis , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Gian Francesco Mureddu, Pompilio Faggiano, Francesco Fattirolli, Preoperative evaluation before non cardiac surgery in subjects older than 65 years , Monaldi Archives for Chest Disease: Vol. 82 No. 1 (2014): Cardiac series
- Cesare Greco, Rivaroxaban in non valvular atrial fibrillation: subgroups analysis , Monaldi Archives for Chest Disease: Vol. 82 No. 1 (2014): Cardiac series
- Sandeep Gupta, Ashlesha Kaushik, Jitendra Gupta, Management and outcomes of patients hospitalized with severe COVID-19 at a tertiary care center in midwestern United States , Monaldi Archives for Chest Disease: Vol. 90 No. 4 (2020)
- Bruno Sposato, Significant gas-exchange improvements reported after roflumilast in two cases of severe COPD , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series - Supplement 1
- Biagio Polla, Roflumilast is effective in reducing COPD related exacerbations and improving CAT score , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series - Supplement 1
- Daniela Parola, Ambra Castagnacci, Sara Salvati, A case report of roflumilast in an elderly COPD patient: improving exercise capacity to improve quality of life , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series - Supplement 1
- Gabriella Guarnieri, Roflumilast succeeds where traditional therapy fails: a case report , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series - Supplement 1
<< < 46 47 48 49 50 51 52 53 54 55 > >>
You may also start an advanced similarity search for this article.
