https://doi.org/10.4081/monaldi.2021.1601
Hammering home the sickle: an instructive case of endobronchial anaplastic large cell lymphoma
Submitted: September 7, 2020
Accepted: February 24, 2021
Published: April 8, 2021
Accepted: February 24, 2021
Abstract Views: 850
PDF: 345
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
It is extremely unusual for primary pulmonary lymphoma, an uncommon occurrence in any form, to be of T-cell origin and to manifest as an endobronchial lesion. Each of these characteristics is rare individually, so cases that combine them are exceptional. We report a patient in whom primary pulmonary anaplastic large cell lymphoma, a T-cell neoplasm, presented with obstruction of the left upper lobe bronchus, resulting in left upper lobe atelectasis and creating the radiographic luftsichel sign. We briefly discuss anaplastic large cell lymphoma as a whole, place our case in the context of previously published literature on endobronchial anaplastic large cell lymphoma, and review the genesis of the luftsichel sign.
Pan Z, Xu ML. T-cell and NK-cell lymphomas in the lung. Semin Diagn Pathol 2020;37:273-82.
DOI: https://doi.org/10.1053/j.semdp.2020.04.003
Solomonov A, Zuckerman T, Goralnik L, et al. Non-Hodgkin's lymphoma presenting as an endobronchial tumor: report of eight cases and literature review. Am J Hematol 2008;83:416-9.
DOI: https://doi.org/10.1002/ajh.21112
Kligerman SJ, Franks TJ, Galvin JR. Primary extranodal lymphoma of the thorax. Radiol Clin North Am 2016;54:673-87.
DOI: https://doi.org/10.1016/j.rcl.2016.03.002
L'Hoste RJ Jr, Filippa DA, Lieberman PH, Bretsky S. Primary pulmonary lymphomas. A clinicopathologic analysis of 36 cases. Cancer 1984;54:1397-406.
DOI: https://doi.org/10.1002/1097-0142(19841001)54:7<1397::AID-CNCR2820540728>3.0.CO;2-4
Cadranel J, Wislez M, Antoine M. Primary pulmonary lymphoma. Eur Respir J 2002;20:750-62.
DOI: https://doi.org/10.1183/09031936.02.00404102
Sammassimo S, Pruneri G, Andreola G, et al. A retrospective international study on primary extranodal marginal zone lymphoma of the lung (BALT lymphoma) on behalf of International Extranodal Lymphoma Study Group (IELSG). Hematol Oncol 2016;34:177-83.
DOI: https://doi.org/10.1002/hon.2243
Rush WL, Andriko JA, Taubenberger JK, et al. Primary anaplastic large cell lymphoma of the lung: a clinicopathologic study of five patients. Mod Pathol 2000;13:1285-92.
DOI: https://doi.org/10.1038/modpathol.3880235
Kim DH, Ko YH, Lee MH, Ree HJ. Anaplastic large cell lymphoma presenting as an endobronchial polypoid mass. Respiration 1998;65:156-8.
DOI: https://doi.org/10.1159/000029248
Chand T, Bansal A, Dua H, Sharma K. Endotracheobronchial lymphoma: Two unusual case reports and review of article. Lung India 2016;33:653-6.
DOI: https://doi.org/10.4103/0970-2113.192873
Von Ende E, Kauffman T, Munoz PA, Martinez-Jiménez S. Primary pulmonary anaplastic large cell lymphoma: A rare malignancy and rare cause of the luftsichel sign. Case Rep Radiol 2018;2018:8574642.
DOI: https://doi.org/10.1155/2018/8574642
Carvalho J, Marques DP, Oliveira I, Claudino C. A rare case of primary pulmonary anaplastic large cell lymphoma. Eur J Case Rep Intern Med 2019;6:001249.
DOI: https://doi.org/10.12890/2019_001249
Blankenbaker DG. The luftsichel sign. Radiology 1998;208:319-20.
DOI: https://doi.org/10.1148/radiology.208.2.9680553
Day K, Oliva I. Signs in cardiopulmonary imaging: luftsichel sign. J Thorac Imaging 2015;30:W1.
DOI: https://doi.org/10.1097/RTI.0000000000000151
Eyre TA, Khan D, Hall GW, Collins GP. Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: current and future perspectives in adult and paediatric disease. Eur J Haematol 2014;93:455-68.
DOI: https://doi.org/10.1111/ejh.12360
Leventaki V, Bhattacharyya S, Lim MS. Pathology and genetics of anaplastic large cell lymphoma. Semin Diagn Pathol 2020;37:57-71.
DOI: https://doi.org/10.1053/j.semdp.2019.12.002
Chiarle R, Voena C, Ambrogio C, et al. The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat Rev Cancer 2008;8:11-23.
DOI: https://doi.org/10.1038/nrc2291
Vose J, Armitage J, Weisenburger D, International T-Cell Lymphoma Project. International peripheral T-cell and natural killer/T-cell lymphoma study: pathology findings and clinical outcomes. J Clin Oncol 2008;26:4124-30.
DOI: https://doi.org/10.1200/JCO.2008.16.4558
Horwitz S, O'Connor OA, Pro B, et al. Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial. Lancet 2019;393:229-40. Erratum in: Lancet 2019;393:228.
Gambacorti-Passerini C, Messa C, Pogliani EM. Crizotinib in anaplastic large-cell lymphoma. N Engl J Med 2011;364:775-6
DOI: https://doi.org/10.1056/NEJMc1013224
Gambacorti Passerini C, Farina F, Stasia A, et al. Crizotinib in advanced, chemoresistant anaplastic lymphoma kinase-positive lymphoma patients. J Natl Cancer Inst 2014;106:djt378.
DOI: https://doi.org/10.1093/jnci/djt378
How to Cite
Abu-Hishmeh, Mohammad, Laura Miranda, Fouzia Shakil, Tauseef Ahmed, and Oleg Epelbaum. 2021. “Hammering Home the Sickle: An Instructive Case of Endobronchial Anaplastic Large Cell Lymphoma”. Monaldi Archives for Chest Disease 91 (3). https://doi.org/10.4081/monaldi.2021.1601.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- B. Chakrabarti, P.D.O. Davies, Pleural tuberculosis , Monaldi Archives for Chest Disease: Vol. 65 No. 1 (2006): Pulmonary series
- C. Zisis, S. Fragoulis, D. Rontogianni, G. Stratakos, I. Bellenis, Malignant triton tumour of the anterior mediastinum as incidental finding , Monaldi Archives for Chest Disease: Vol. 65 No. 4 (2006): Pulmonary series
- Marinella Gattone, Pantaleo Giannuzzi, Interventional Strategies in early Atherosclerosis , Monaldi Archives for Chest Disease: Vol. 66 No. 1 (2006): Cardiac series
- U. Caterino, G. Dialetto, F.E. Covino, G. Mazzarella, E. Grella, M. Massimo, The usefulness of transesophageal echocardiography in the staging of locally advanced lung cancer , Monaldi Archives for Chest Disease: Vol. 67 No. 1 (2007): Pulmonary series
- G.V. Scagliotti, S. Novello, G. Selvaggi, Cytotoxic chemotherapy in advanced non-small cell lung cancer , Monaldi Archives for Chest Disease: Vol. 63 No. 4 (2005): Pulmonary series
- L. Casali, G. Pinchi, E. Puxeddu, Doping and Respiratory System , Monaldi Archives for Chest Disease: Vol. 67 No. 1 (2007): Pulmonary series
- Carmine Riccio, Marco Malvezzi Caracciolo, Maurizio G. Abrignani, Commento editoriale alle linee guida britanniche sull’ipertensione arteriosa 2006: “Hypertension: management of hypertension in adults in primary care. Partial update†, Monaldi Archives for Chest Disease: Vol. 66 No. 4 (2006): Cardiac series
- Marie Christine Iliou, Jean Christophe Blanchard, Aurélia Lamar-Tanguy, Pascal Cristofini, François Ledru, Cardiac rehabilitation in patients with pacemakers and implantable cardioverter defibrillators , Monaldi Archives for Chest Disease: Vol. 86 No. 1-2 (2016): Cardiac series
- Margaret Cupples, Neil Heron, What to do after cardiac rehabilitation programs: the role of the general practitioner in cardiovascular prevention , Monaldi Archives for Chest Disease: Vol. 86 No. 1-2 (2016): Cardiac series
- Fabrizio Corsini, Anna Scaglione, Maria Iacomino, Giuseppe Mascia, Saverio Melorio, Carmine Riccio, Salvatore Romano, Alfredo Vetrano, Silvana Celardo, Giancarlo Corsini, Carmelo Chieffo, Acute myocardial infarction in the elderly. A case-control study with a younger population and review of literature , Monaldi Archives for Chest Disease: Vol. 66 No. 1 (2006): Cardiac series
<< < 52 53 54 55 56 57 58 59 60 61 > >>
You may also start an advanced similarity search for this article.
