https://doi.org/10.4081/monaldi.2021.1638
Cytomegalovirus pneumonia in an immunocompetent host with primary ciliary dyskinesia: A case report
Submitted: October 12, 2020
Accepted: April 14, 2021
Published: April 22, 2021
Accepted: April 14, 2021
Abstract Views: 1265
PDF: 519
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Primary ciliary dyskinesia (PCD) is an autosomal-recessive inherited disease caused by mutations in genes involved in ciliary structure and function leading to impaired mucociliary clearance and repeated or chronic, usually bacterial, infections of the upper and lower airways and decreased lung function and bronchiectasis. Cytomegalovirus (CMV) is a DNA virus that usually causes subclinical infection and in 10% of the patients causes a mononucleosis-like syndrome. CMV is a causative agent of serious illness in vulnerable immunocompromised groups such as transplant recipients, patients with immunodeficiency or malignancy and neonates. Life-threatening infection due to CMV, including CMV pneumonia, is not common in immunocompetent patients. In this report we describe a case of an otherwise immunocompetent woman, suffering from PCD, who developed severe CMV pneumonia.
Knowles MR, Zariwala M, Leigh M. Primary Ciliary Dyskinesia. Clin Chest Med 2016;37:449-61.
DOI: https://doi.org/10.1016/j.ccm.2016.04.008
Lucas JS, Barbato A, Collins SA. European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia. Eur Respir J 2017;49:1601090.
DOI: https://doi.org/10.1183/13993003.01090-2016
Shapiro AJ, Zariwala MA, Ferkol T, et al. Diagnosis monitoring and treatment of primary ciliary dyskinesia: PCD Foundation consensus recommendations based on state of the art review. Pediatr Pulmonol 2016;51:115-32.
DOI: https://doi.org/10.1002/ppul.23304
Grilli E, Galati V, Bordi L, et al. Cytomegalovirus pneumonia in immunocompetent host: case report and literature review. J Clin Viro. 2012;55:356-9.
DOI: https://doi.org/10.1016/j.jcv.2012.08.010
Klemola E, Stenstrom R, von Essen R. Pneumonia as a clinical manifestation of cytomegalovirus infection in previously healthy adults. Scand J Infect Dis 1972;4:7-10.
DOI: https://doi.org/10.3109/inf.1972.4.issue-1.02
Manian FA, Smith T. Ganciclovir for the treatment of cytomegalovirus pneumonia in an immunocompetent host. Clin Infect Dis 1993;17:137–8.
DOI: https://doi.org/10.1093/clinids/17.1.137-a
Halimi C, Hajeje H, Mouchet M, et al. [CMV lung infection in a non-mmunocompromised patients treated with ganciclovir].[Article in French]. Ann Med Intern 1993;144:502–4.
EddlestonM, Peacock S, JuniperM, et al. Severe cytomegalovirus infection in immunocompetent patients. Clin Infect Dis 1997;24:52–6.
DOI: https://doi.org/10.1093/clinids/24.1.52
McCormack JG, Bowler SD, Donnelly JE, et al. Successful treatment of severe cytomegalovirus infection with ganciclovir in an immunocompetent host. Clin Infect Dis 1998;26:1007–8.
DOI: https://doi.org/10.1086/517635
Karakelides H, Aubry MC, Ryu JH. Cytomegalovirus pneumonia mimicking lung cancer in an immunocompetent host. Mayo Clin Proc 2003;78:488–90.
DOI: https://doi.org/10.4065/78.4.488
Abgueguen P, Delbos V, Chennebault JM, et al. Vascular thrombosis and acute cytomegalovirus infection in immunocompetent patients: report of 2 cases and literature review. Clin Infect Dis 2003;36:E134-9.
DOI: https://doi.org/10.1086/374664
Cunha BA, Pherez F, Walls N. Severe cytomegalovirus (CMV) community-acquired pneumonia (CAP) in a nonimmunocompromised host. Heart Lung 2009;38:243-8.
DOI: https://doi.org/10.1016/j.hrtlng.2008.05.008
Barclay A, Naseer R, McGann H, et al. Cytomegalovirus pneumonia in an immunocompetent adult: a case report. Acute Med 2011;10:197–9.
Ii K, Hizama K, Katuses R. Generalized cytomegalic inclusion disease presenting as an infectious mononucleosis syndrome in a previously healthy adult-an autopsy study. Acta Pathol Jpn 1972;22:723–37.
Back E, Hoglunf C, Malmlund HO. Cytomegalovirus infection associated with severe encephalitis. Scand J Infect Dis 1977;9:141–3.
DOI: https://doi.org/10.3109/inf.1977.9.issue-2.17
Teixidor HS, Honig CL, Norsoph E, et al. Cytomegalovirus infection of the alimentary canal: radilogical findings with pathologic correlation. Radiology 1987;163:317-23.
DOI: https://doi.org/10.1148/radiology.163.2.3031723
Alanin MC, Nielsen KG, von Buchwald C, et al. A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia. Clin Microbiol Infect 2015;21:1093.e1-7.
DOI: https://doi.org/10.1016/j.cmi.2015.08.020
Wijers CD, Chmiel JF, Gaston BM. Bacterial infections in patients with primary ciliary dyskinesia: Comparison with cystic fibrosis. Chron Respir Dis 2017;14:392-406.
DOI: https://doi.org/10.1177/1479972317694621
Roden L, Görlich D, Omran H, et al. A retrospective analysis of the pathogens in the airways of patients with primary ciliary dyskinesia. Respir Med 2019;156:69-77.
DOI: https://doi.org/10.1016/j.rmed.2019.08.009
Sakhaee F, Vaziri F, Bahramali G, et al. pulmonary infection related to mimivirus in patient with primary ciliary dyskinesia. Emerg Infect Dis 2020;26:2524-6.
DOI: https://doi.org/10.3201/eid2610.191613
How to Cite
Georgakopoulou, Vasiliki Epameinondas, Dimitrios Mermigkis, Despoina Melemeni, Aikaterini Gkoufa, Christos Damaskos, Nikolaos Garmpis, Anna Garmpi, Nikolaos Trakas, and Xanthi Tsiafaki. 2021. “Cytomegalovirus Pneumonia in an Immunocompetent Host With Primary Ciliary Dyskinesia: A Case Report”. Monaldi Archives for Chest Disease 91 (3). https://doi.org/10.4081/monaldi.2021.1638.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Sanatkumar Bharamu Nyamagoud, A H M Viswanath Swamy, Anchu S P, Sonia S Gaitonde, Jaison M Johnson, Vishwanath Hegadal, Retraction: Prescription analysis emphasizing on medication adherence of antibiotics for lower respiratory tract infection , Monaldi Archives for Chest Disease: Early Access
- Joana Almeida Borges, Antonio M. Esquinas, Biphasic cuirass ventilation in the escalation of non-invasive ventilation in COVID-19: Case report and review , Monaldi Archives for Chest Disease: Vol. 93 No. 4 (2023)
- Syed Muhammad Zubair, Muhammad Mustansir Mehdi Khan, Yasmin Rahim, Hamza Ahmed Ibad, Muhammad Irfan, Impact of immune status on the clinical characteristics, treatment outcomes and mortality of pulmonary nocardiosis: a retrospective analysis in a tertiary care hospital from a low- to middle-income country , Monaldi Archives for Chest Disease: Vol. 94 No. 2 (2024)
- Abhay Joglekar, Subhasis Roy Choudhury, Chandra Vibhash, Manisha Kumar, Amit Gupta, Risk factors and outcome of antenatally diagnosed congenital diaphragmatic hernia following in-utero transfer in a busy public-sector tertiary care center in North India , Monaldi Archives for Chest Disease: Early Access
- Rozandeep Kaur, Neha Uppal, Vibha Uppal, Anju Sharma, Impaired glycemic control as a risk factor for reduced lung function in the Indian diabetic population , Monaldi Archives for Chest Disease: Early Access
- Shivam Garg, Vishnukanth Govindaraj, Dharm Prakash Dwivedi, Kalayarasan Raja, Elamurugan Palanivel Theerthar, Postoperative pulmonary complications in patients undergoing upper abdominal surgery: risk factors and predictive models , Monaldi Archives for Chest Disease: Early Access
- Martina Maria Seminara, Dina Visca, Alice Claudia Repossi, Antonio Spanevello, Mycobacterium chimaera: a case report from Italy , Monaldi Archives for Chest Disease: Early Access
- Rahul Kumar, Dipti Gothi, Shweta Anand, Shazia Khan, Nipun Malhotra, Survival among patients with lung cancer managed at a tertiary care center in North India , Monaldi Archives for Chest Disease: Early Access
- Musaib Alavi, Waris Ali, Alaeddin Sagar, Majid Shafiq, Muhammad Azhar, Akbar S. Ali, Moiz Salahuddin, Real-world effectiveness and safety of handheld ultrasound in pleural procedures , Monaldi Archives for Chest Disease: Early Access
- Mamta Singh, Kunal Deokar, Bibhuti Prassan Sinha, Jinish Doshi, CDS Katoch, Infective pulmonary diseases and the eye: a narrative review , Monaldi Archives for Chest Disease: Early Access
<< < 19 20 21 22 23 24 25 26 27 28 > >>
You may also start an advanced similarity search for this article.
