https://doi.org/10.4081/monaldi.2021.1638
Cytomegalovirus pneumonia in an immunocompetent host with primary ciliary dyskinesia: A case report
Submitted: October 12, 2020
Accepted: April 14, 2021
Published: April 22, 2021
Accepted: April 14, 2021
Abstract Views: 1394
PDF: 542
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Primary ciliary dyskinesia (PCD) is an autosomal-recessive inherited disease caused by mutations in genes involved in ciliary structure and function leading to impaired mucociliary clearance and repeated or chronic, usually bacterial, infections of the upper and lower airways and decreased lung function and bronchiectasis. Cytomegalovirus (CMV) is a DNA virus that usually causes subclinical infection and in 10% of the patients causes a mononucleosis-like syndrome. CMV is a causative agent of serious illness in vulnerable immunocompromised groups such as transplant recipients, patients with immunodeficiency or malignancy and neonates. Life-threatening infection due to CMV, including CMV pneumonia, is not common in immunocompetent patients. In this report we describe a case of an otherwise immunocompetent woman, suffering from PCD, who developed severe CMV pneumonia.
Knowles MR, Zariwala M, Leigh M. Primary Ciliary Dyskinesia. Clin Chest Med 2016;37:449-61.
DOI: https://doi.org/10.1016/j.ccm.2016.04.008
Lucas JS, Barbato A, Collins SA. European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia. Eur Respir J 2017;49:1601090.
DOI: https://doi.org/10.1183/13993003.01090-2016
Shapiro AJ, Zariwala MA, Ferkol T, et al. Diagnosis monitoring and treatment of primary ciliary dyskinesia: PCD Foundation consensus recommendations based on state of the art review. Pediatr Pulmonol 2016;51:115-32.
DOI: https://doi.org/10.1002/ppul.23304
Grilli E, Galati V, Bordi L, et al. Cytomegalovirus pneumonia in immunocompetent host: case report and literature review. J Clin Viro. 2012;55:356-9.
DOI: https://doi.org/10.1016/j.jcv.2012.08.010
Klemola E, Stenstrom R, von Essen R. Pneumonia as a clinical manifestation of cytomegalovirus infection in previously healthy adults. Scand J Infect Dis 1972;4:7-10.
DOI: https://doi.org/10.3109/inf.1972.4.issue-1.02
Manian FA, Smith T. Ganciclovir for the treatment of cytomegalovirus pneumonia in an immunocompetent host. Clin Infect Dis 1993;17:137–8.
DOI: https://doi.org/10.1093/clinids/17.1.137-a
Halimi C, Hajeje H, Mouchet M, et al. [CMV lung infection in a non-mmunocompromised patients treated with ganciclovir].[Article in French]. Ann Med Intern 1993;144:502–4.
EddlestonM, Peacock S, JuniperM, et al. Severe cytomegalovirus infection in immunocompetent patients. Clin Infect Dis 1997;24:52–6.
DOI: https://doi.org/10.1093/clinids/24.1.52
McCormack JG, Bowler SD, Donnelly JE, et al. Successful treatment of severe cytomegalovirus infection with ganciclovir in an immunocompetent host. Clin Infect Dis 1998;26:1007–8.
DOI: https://doi.org/10.1086/517635
Karakelides H, Aubry MC, Ryu JH. Cytomegalovirus pneumonia mimicking lung cancer in an immunocompetent host. Mayo Clin Proc 2003;78:488–90.
DOI: https://doi.org/10.4065/78.4.488
Abgueguen P, Delbos V, Chennebault JM, et al. Vascular thrombosis and acute cytomegalovirus infection in immunocompetent patients: report of 2 cases and literature review. Clin Infect Dis 2003;36:E134-9.
DOI: https://doi.org/10.1086/374664
Cunha BA, Pherez F, Walls N. Severe cytomegalovirus (CMV) community-acquired pneumonia (CAP) in a nonimmunocompromised host. Heart Lung 2009;38:243-8.
DOI: https://doi.org/10.1016/j.hrtlng.2008.05.008
Barclay A, Naseer R, McGann H, et al. Cytomegalovirus pneumonia in an immunocompetent adult: a case report. Acute Med 2011;10:197–9.
Ii K, Hizama K, Katuses R. Generalized cytomegalic inclusion disease presenting as an infectious mononucleosis syndrome in a previously healthy adult-an autopsy study. Acta Pathol Jpn 1972;22:723–37.
Back E, Hoglunf C, Malmlund HO. Cytomegalovirus infection associated with severe encephalitis. Scand J Infect Dis 1977;9:141–3.
DOI: https://doi.org/10.3109/inf.1977.9.issue-2.17
Teixidor HS, Honig CL, Norsoph E, et al. Cytomegalovirus infection of the alimentary canal: radilogical findings with pathologic correlation. Radiology 1987;163:317-23.
DOI: https://doi.org/10.1148/radiology.163.2.3031723
Alanin MC, Nielsen KG, von Buchwald C, et al. A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia. Clin Microbiol Infect 2015;21:1093.e1-7.
DOI: https://doi.org/10.1016/j.cmi.2015.08.020
Wijers CD, Chmiel JF, Gaston BM. Bacterial infections in patients with primary ciliary dyskinesia: Comparison with cystic fibrosis. Chron Respir Dis 2017;14:392-406.
DOI: https://doi.org/10.1177/1479972317694621
Roden L, Görlich D, Omran H, et al. A retrospective analysis of the pathogens in the airways of patients with primary ciliary dyskinesia. Respir Med 2019;156:69-77.
DOI: https://doi.org/10.1016/j.rmed.2019.08.009
Sakhaee F, Vaziri F, Bahramali G, et al. pulmonary infection related to mimivirus in patient with primary ciliary dyskinesia. Emerg Infect Dis 2020;26:2524-6.
DOI: https://doi.org/10.3201/eid2610.191613
How to Cite
Georgakopoulou, Vasiliki Epameinondas, Dimitrios Mermigkis, Despoina Melemeni, Aikaterini Gkoufa, Christos Damaskos, Nikolaos Garmpis, Anna Garmpi, Nikolaos Trakas, and Xanthi Tsiafaki. 2021. “Cytomegalovirus Pneumonia in an Immunocompetent Host With Primary Ciliary Dyskinesia: A Case Report”. Monaldi Archives for Chest Disease 91 (3). https://doi.org/10.4081/monaldi.2021.1638.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Halil Yanardag, Cuneyt Tetikkurt, Muammer Bilir, Carpal tunnel syndrome associated with sarcoidosis in identical twin patients , Monaldi Archives for Chest Disease: Vol. 89 No. 3 (2019)
- Angelo Carretta, Paola Ciriaco, Alessandro Bandiera, Piergiorgio Muriana, Gianluigi Arrigoni, Giampiero Negri, Therapeutic strategy for tracheal chondrosarcoma: report of two cases , Monaldi Archives for Chest Disease: Vol. 90 No. 1 (2020)
- Nipun Malhotra, Nitesh Gupta, Somya Ish, Pranav Ish, COVID-19 in intensive care. Some necessary steps for health care workers , Monaldi Archives for Chest Disease: Vol. 90 No. 1 (2020)
- Shekhar Kunal, Kashish Gupta, Shashi Mohan Sharma, Vijay Pathak, Shruti Mittal, Chandrakant Tarke, Cardiovascular system and COVID-19: perspectives from a developing country , Monaldi Archives for Chest Disease: Vol. 90 No. 2 (2020)
- Nicholas Zareifopoulos, Maria Lagadinou, Anastasia Karela, Christina Platanaki, Gerasimos Karantzogiannis, Dimitrios Velissaris, Management of COVID-19: the risks associated with treatment are clear, but the benefits remain uncertain , Monaldi Archives for Chest Disease: Vol. 90 No. 2 (2020)
- Kamal Kant Sahu, Ajay Kumar Mishra, Kevin Martin, Iryna Chastain, COVID-19 and restrictive lung disease: A deadly combo to trip off the fine balance , Monaldi Archives for Chest Disease: Vol. 90 No. 2 (2020)
- Sunil Mahavar, Princy Tyagi, Abhishek Agrawal, Sudhir Bhandari, Subrata Banerjee, Raman Sharma, Prakash Keshwani, Clinical and epidemiological profile of Indian COVID-19 patients from Jaipur: a descriptive study , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Eduardo Eriko Tenório de França, Ubirace Elihimas Junior, Paulo Adriano Schwingel, Celso R.F. Carvalho, Maria do Socorro Brasileiro-Santos, Distinct phenotypes in COVID-19 may require distinct pulmonary rehabilitation strategies , Monaldi Archives for Chest Disease: Vol. 90 No. 4 (2020)
- Iffat Khanum, Fatima Samar, Yousuf Fatimah, Awan Safia, Aziz Adil, Habib Kiren, Nasir Nosheen, Mahmood Faisal, Jamil Bushra, Role of awake prone positioning in patients with moderate-to-severe COVID-19: an experience from a developing country , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Archana Malik, Manju Rajaram, Mahesh Babu Vemuri, Madhusmita Mohanty Mohapatra, Srinivas BH, Naren Chandra V, Varied foci of primary benign schwannoma of the thorax: a case series , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
<< < 24 25 26 27 28 29 30 31 32 33 > >>
You may also start an advanced similarity search for this article.
