Combined Pulmonary Fibrosis and Emphysema in a welder

Submitted: December 3, 2015
Accepted: December 3, 2015
Published: December 3, 2015
Abstract Views: 1371
PDF: 887
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Authors

Combined pulmonary fibrosis and emphysema (CPFE) syndrome is an uncommon entity characterised by emphysema of the upper lobes and diffuse fibrosis of the lower lobes and carries a bad prognosis with the onset of pulmonary hypertension. Lung involvement due to exposures suffered by welders is generally considered benign though, rarely, a diffuse interstitial fibrotic disease has been reported. CPFE syndrome has however never been reported in welders. A 65-year-old man, welder by occupation and an ex-smoker, presented with progressive exertional dyspnoea associated with dry cough noticed for the last four months. On examination, there was mild tachypnea, clubbing and bilateral basal velcro crepitations on chest auscultation. Lung function test revealed mild mixed ventilatory impairment with severe diffusion defect. HRCT chest showed bilateral upper lobe emphysema and diffuse interstitial fibrosis in the lower lobes. Transbronchial lung biopsy revealed interstitial fibrosis, chronic inflammation and iron deposits. A diagnosis of combined pulmonary fibrosis with emphysema (CPFE) with interstitial pulmonary siderofibrosis (IPS) was established. A review of literature did not show any other report of a similar nature.

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How to Cite

Roshan, R., M. Gupta, R. Kulshrestha, B. Menon, and S.K. Chhabra. 2015. “Combined Pulmonary Fibrosis and Emphysema in a Welder”. Monaldi Archives for Chest Disease 77 (1). https://doi.org/10.4081/monaldi.2012.164.

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