https://doi.org/10.4081/monaldi.2021.1702
The challenging management of a giant intrathoracic desmoid tumour: a case report
Submitted: November 26, 2020
Accepted: February 24, 2021
Published: March 8, 2021
Accepted: February 24, 2021
Abstract Views: 802
PDF: 551
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Desmoid tumours are rare, locally aggressive neoplasms exhibiting high tendency for recurrence, even after complete resection. Only 1 in 5 of them originates from the chest wall, usually measuring less than 10 cm at diagnosis. Herein, we report the case of a woman presenting with symptoms of gradual lung compression by a giant desmoid tumour occupying the entire hemithorax. She underwent complete surgical resection of the tumour and chest wall reconstruction. She had disease recurrence 15 months later and currently remains under regular follow-up. The management of intrathoracic desmoid tumours is challenging because they are usually not diagnosed until they become large enough to cause compression symptoms. While medical management is the primary modality of treatment, surgery could be considered in selected cases where significant symptoms arise, and the functional status is impaired secondary to the tumour. Adjuvant radiotherapy to minimise the risk of local recurrence should also be considered.
Sakorafas GH, Nissotakis C, Peros G. Abdominal desmoid tumors. Surg Oncol 2007;16:131–42.
McKinnon JG, Neifeld JP, Kay S, et al. Management of desmoid tumors. Surg Gynecol Obstet 1989;169:104–6.
Fletcher CD, Unni KK, Mertens F. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002.
Shinagare AB, Ramaiya NH, Jagannathan JP, et al. A to Z of desmoid tumors. AJR Am J Roentgenol 2011;197:W1008–14.
Howard JH, Pollock RE. Intra-abdominal and abdominal wall desmoid fibromatosis. Oncol Ther 2016;4:57–72.
Deyrup AT, Tretiakova M, Montag AG. Estrogen receptor-β expression in extraabdominal fibromatoses. Cancer 2006;106:208-13.
Lee JC, Thomas JM, Phillips S, et al. Aggressive fibromatosis: MRI Features with pathologic correlation. AJR Am J Roentgenol 2006;186:247–54.
Koshariya M, Shukla S, Khan Z, et al. Giant desmoid tumor of the anterior abdominal wall in a young female: a case report. Case Rep Surg 2013;2013:780862.
Kovačević K, Obad-Kovačević D, Popić-Ramač J. Sporadic giant intra-abdominal desmoid tumor: A radiological case report. Mol. Clin. Oncol. 2017;6:896–8.
Weiss SW, Goldblum JR. Fibromatoses. In: Weiss SW, Goldblum JR, editors. Enzinger and Weiss’s soft tissue tumors. St. Louis: Mosby; 2001. p. 309–46.
Kasper B, Baumgarten C, Bonvalot S, et al. Management of sporadic desmoid-type fibromatosis: A European consensus approach based on patients’ and professionals’ expertise – A Sarcoma Patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group. Eur J Cancer 2015;51:127–36.
Kasper B, Baumgarten C, Garcia J, et al. An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG). Ann Oncol 2017;28:2399–408.
Briand S, Barbier O, Biau D, et al. Wait-and- see policy as a first-line management for extra-abdominal desmoid tumors. J Bone Joint Surg Am 2014;96:631–8.
Fiore M, Rimareix F, Mariani L, et al. Desmoid-type fibromatosis: A front-line conservative approach to select patients for surgical treatment. Ann Surg Oncol 2009;16:2587–93.
Bonvalot S, Eldweny H, Haddad V, et al. Extra-abdominal primary fibromatosis: Aggressive management could be avoided in a subgroup of patients. Eur J Surg Oncol 2008;34:462–8.
Colombo C, Miceli R, Le Péchoux C, et al. Sporadic extra abdominal wall desmoid-type fibromatosis: Surgical resection can be safely limited to a minority of patients. Eur J Cancer 2015;51:186–92.
Bonvalot S, Ternès N, Fiore M, et al. Spontaneous regression of primary abdominal wall desmoid tumors: More common than previously thought. Ann Surg Oncol 2013;20:4096–102.
Roussin S, Mazouni C, Rimareix F, et al. Toward a new strategy in desmoid of the breast? Eur J Surg Oncol 2015;41:571–6.
Joglekar SB, Rose PS, Sim F, et al. Current perspectives on desmoid tumors: the mayo clinic approach. Cancers (Basel) 2011;3:3143–55.
Micke O, Seegenschmiedt MH, German Cooperative Group on Radiotherapy for Benign Diseases. Radiation therapy for aggressive fibromatosis (desmoid tumors): Results of a national patterns of Care Study. Int J Radiat Oncol 2005;61:882–91.
How to Cite
Kakos, Christos, Savvas Lampridis, Georgios Geropoulos, Reena Khiroya, Achilleas Antonopoulos, Sofoklis Mitsos, and Nikolaos Panagiotopoulos. 2021. “The Challenging Management of a Giant Intrathoracic Desmoid Tumour: A Case Report”. Monaldi Archives for Chest Disease 91 (3). https://doi.org/10.4081/monaldi.2021.1702.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Anna Stainer, Paola Faverio, Francesca Bono, Alberto Pesci, An unusual presentation of pulmonary lymphoma: When diffuse ground glass opacities can mean anything , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Rodolfo Citro, Marco Mariano Patella, Gennaro Provenza, Giovanni Gregorio, Eduardo Bossone, Type A Acute Aortic Dissection in Nonagenarian: Rare but Possible , Monaldi Archives for Chest Disease: Vol. 68 No. 3 (2007): Cardiac series
- K. Psathakis, V. Skouras, F. Chatzivassiloglou, K. Tsintiris, Osteophytes may be a rare cause of recurrent pleural effusions , Monaldi Archives for Chest Disease: Vol. 79 No. 2 (2013): Pulmonary series
- Alfonso Sforza, Maria V. Carlino, Giovanni Albano, Maria I. Arnone, Giuliano De Stefano, Andrea D'Amato, Federica De Pisapia, Giovanni de Simone, Costantino Mancusi, A challenging diagnosis of dyspnea: A case report of contralateral reexpansion pulmonary edema , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Gabriella Guarnieri, Roflumilast succeeds where traditional therapy fails: a case report , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series - Supplement 1
- Daniela Parola, Ambra Castagnacci, Sara Salvati, A case report of roflumilast in an elderly COPD patient: improving exercise capacity to improve quality of life , Monaldi Archives for Chest Disease: Vol. 79 No. 3-4 (2013): Pulmonary series - Supplement 1
- Shi-Min Yuan, Amihay Shinfeld, Ehud Raanani, Mitral valve cleft associated with secundum atrial septal defect: case report and review of the literature , Monaldi Archives for Chest Disease: Vol. 68 No. 1 (2007): Cardiac series
- Stefania Angela Di Fusco, Nadia Aspromonte, Stefano Aquilani, Luca Mele, Furio Colivicchi, Emergency reversal of vitamin-K antagonists related over-anticoagulation: case report and brief overview on the role of Prothrombin Complex Concentrate , Monaldi Archives for Chest Disease: Vol. 80 No. 4 (2013): Cardiac Series
- Emanuela Barisione, Rita Bianchi, Roberto Fiocca, Mario Salio, Pneumomediastinum after transbronchial cryobiopsy , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- Yannis Dimitroglou, Ioannis Loulakas, Maria Chounti, Michail Megalakakis, Eleni Karavana, Panagiotis Hountis, Unusual symptomatic late onset presentation of aberrant right subclavian artery: report of two cases and short literature review , Monaldi Archives for Chest Disease: Vol. 87 No. 1 (2017)
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
