https://doi.org/10.4081/monaldi.2021.1709
Pulmonary alveolar microlithiasis: Blizzard of lung
Submitted: December 1, 2020
Accepted: April 22, 2021
Published: June 10, 2021
Accepted: April 22, 2021
Abstract Views: 1533
PDF: 669
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Pulmonary alveolar microlithiasis (PAM) is a rare inherited disorder in which patients present with either nonspecific signs and symptoms or are asymptomatic. Clinical-radiological dissociation is a commonly seen feature of the disease. Majority of cases are diagnosed in second and third decade of life, although presentation in paediatric and elderly population is also reported. Pathognomonic radiological findings, with normal calcium and phosphate levels can confirm the diagnosis without the need of further investigations in large number of cases. A high index of suspicion and knowledge of the disease is of paramount importance as it has a wide range of presentation and variable course thus posing a diagnostic challenge. We present two cases of this rare disease in elderly females with distinct presentations although with similar and characteristic radiological findings along with a brief review of literature of the disease.
Castellana G, Castellana G, Gentile M, et al. Pulmonary alveolar microlithiasis: Review of the 1022 cases reported worldwide. Eur Respir Rev 2015;24:607-20.
DOI: https://doi.org/10.1183/16000617.0036-2015
Tendolkar M. An “Orphan” in search of a treatment: Pulmonary alveolar microlithiasis. Lung India 2019;36:553.
DOI: https://doi.org/10.4103/lungindia.lungindia_437_19
Viswananthan R. Pulmonary alveolar microlithiasis. Thorax 1962;17:251-6.
DOI: https://doi.org/10.1136/thx.17.3.251
Harbitz F. Extensive calcification of the lungs as a distinct disease. Arch Intern Med (Chic) 1918;XXI:139-46.
DOI: https://doi.org/10.1001/archinte.1918.00090070150012
Saito A, McCormack FX. Pulmonary Alveolar Microlithiasis. Clin Chest Med. 2016;37:441-8.
DOI: https://doi.org/10.1016/j.ccm.2016.04.007
Castellana G, Gentile M, Castellana R, et al. Pulmonary alveolar microlithiasis: clinical features, evolution of the phenotype, and review of the literature. Am J Med Genet 2002;111:220–4.
DOI: https://doi.org/10.1002/ajmg.10530
Tachibana T, Hagiwara K, Johkoh T. Pulmonary alveolar microlithiasis: Review and management. Curr Opin Pulm Med 2009;15:486-90.
DOI: https://doi.org/10.1097/MCP.0b013e32832d03bb
Castellana G, Carone D, Castellana M. Microlithiasis of seminal vesicles and severe oligoasthenospermia in pulmonary alveolar microlithiasis (PAM): report of an unusual sporadic case. Int J Fertil Steril 2015; 9:137-40.
Balikian JP, Fuleihan FJ, Nucho CN. Pulmonary alveolar microlithiasis. Report of five cases with special reference to roentgen manifestations. Am J Roentgenol Radium Ther Nucl Med 1968;103:509-18.
DOI: https://doi.org/10.2214/ajr.103.3.509
Felson B. Thoracic calcifications. Dis Chest 1969;56:330-43.
DOI: https://doi.org/10.1378/chest.56.4.330
Cluzel P, Grenier P, Bernadac P, et al. Pulmonary alveolar microlithiasis: Ct findings. J Comput Assist Tomog. 1991;15:938-42.
DOI: https://doi.org/10.1097/00004728-199111000-00006
Pracyk JB, Simonson SG, Young SL, et al. Composition of lung lavage in pulmonary alveolar microlithiasis. Respiration 1996;63:254-60.
DOI: https://doi.org/10.1159/000196556
Ganesan N, Ambroise MM, Ramdas A, et al. Pulmonary alveolar microlithiasis: an interesting case report with systematic review of Indian literature. Front Med 2015;9:229-38.
DOI: https://doi.org/10.1007/s11684-015-0394-y
Belém LC, Zanetti G, Souza AS, et al. Metastatic pulmonary calcification: State-of-the-art review focused on imaging findings. Respir Med 2014;108:668-76.
DOI: https://doi.org/10.1016/j.rmed.2014.01.012
Ozcelik U, Yalcin E, Arıyurek M, et al. Long-term results of disodium etidronate treatment in pulmonary alveolar microlithiasis. Pediatr Pulmonol 2010;45:514-7.
DOI: https://doi.org/10.1002/ppul.21209
Stamatis G, Zerkowski H, Doetsch N, et al. Sequential bilateral lung transplantation for pulmonary alveolar microlithiasis. Ann Thorac Surg 1993;56:972-5.
DOI: https://doi.org/10.1016/0003-4975(93)90370-W
Jindal A, Rahulan V, Balasubramani G, et al. Pulmonary alveolar microlithiasis: A rare disease treated with lung transplantation, first case from India. Lung India 2019;36:546.
DOI: https://doi.org/10.4103/lungindia.lungindia_50_19
How to Cite
Mittal, Richa, Rohit Kumar, Juvva Kishan Srikanth, Siddharth Raj Yadav, Ravi Chandak, and Shibdas Chakrabarti. 2021. “Pulmonary Alveolar Microlithiasis: Blizzard of Lung”. Monaldi Archives for Chest Disease 91 (4). https://doi.org/10.4081/monaldi.2021.1709.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- R.G. Pinckney, R. O’Brien, J.F. Piccirillo, B. Littenberg, Evaluation of co-morbidity indices in patients admitted for Chronic Obstructive Pulmonary Disease , Monaldi Archives for Chest Disease: Vol. 61 No. 4 (2004): Pulmonary series
- Cuneyt Tetikkurt, Bahar Kubat, Cigdem Kulahci, Seza Tetikkurt, Buket Caliskaner Ozturk, Assessment score for the diagnosis of a case with pleuroparenchymal fibroelastosis , Monaldi Archives for Chest Disease: Vol. 91 No. 3 (2021)
- Debasis Behera, J C Suri, Pranav Ish, Ruchi Rekha Behera, Shibdas Chakrabarti, Viswesvaran Balasubramanian, Role of esophageal manometry in polysomnography of patients with chronic respiratory failure , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Alfonso Sforza, Maria V. Carlino, Giovanni Albano, Maria I. Arnone, Giuliano De Stefano, Andrea D'Amato, Federica De Pisapia, Giovanni de Simone, Costantino Mancusi, A challenging diagnosis of dyspnea: A case report of contralateral reexpansion pulmonary edema , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- RK Srivastava, Pranav Ish, *Safdarjung COVID-19 Vaccination group, The initial experience of COVID-19 vaccination from a tertiary care centre of India , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Manu Dogra, Surabhi Jaggi, Deepak Aggarwal, Seema Gupta, Varinder Saini, Jasbinder Kaur, Role of interleukin-6 and insulin resistance as screening markers for metabolic syndrome in patients of chronic obstructive pulmonary disease. A hospital-based cross-sectional study , Monaldi Archives for Chest Disease: Vol. 92 No. 3 (2022)
- Sunil K. Chhabra, Devi Jyoti Dash, Concurrent sensitization to Aspergillus Fumigatus in tropical pulmonary eosinophilia , Monaldi Archives for Chest Disease: Vol. 81 No. 1-2 (2015): Pulmonary series
- Pankti Sheth, Shibdas Chakrabarti, Neeraj Kumar Gupta, Pranav Ish, Rohit Kumar, Nitesh Gupta, A middle-aged lady with near-fatal respiratory failure , Monaldi Archives for Chest Disease: Vol. 92 No. 3 (2022)
- S. Nardini, R. Cagnin, G. Invernizzi, A. Ruprecht, R. Boffi, S. Formentini, Indoor particulate matter measurement as a tool in the process of the implementation of Smoke-free Hospitals , Monaldi Archives for Chest Disease: Vol. 61 No. 3 (2004): Pulmonary series
- Monika Bansal, Komaldeep Kaur, Aditi Gupta, Deepak Goyal, Nidhi Girdhar, Vishal Chopra, Sanjeev Bhagat, Akhil D. Goel, Prevalence of aspergillus skin hypersensitivity in allergic rhinitis , Monaldi Archives for Chest Disease: Vol. 91 No. 3 (2021)
<< < 13 14 15 16 17 18 19 20 21 22 > >>
You may also start an advanced similarity search for this article.
