https://doi.org/10.4081/monaldi.2021.1709
Pulmonary alveolar microlithiasis: Blizzard of lung
Submitted: December 1, 2020
Accepted: April 22, 2021
Published: June 10, 2021
Accepted: April 22, 2021
Abstract Views: 1539
PDF: 671
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Pulmonary alveolar microlithiasis (PAM) is a rare inherited disorder in which patients present with either nonspecific signs and symptoms or are asymptomatic. Clinical-radiological dissociation is a commonly seen feature of the disease. Majority of cases are diagnosed in second and third decade of life, although presentation in paediatric and elderly population is also reported. Pathognomonic radiological findings, with normal calcium and phosphate levels can confirm the diagnosis without the need of further investigations in large number of cases. A high index of suspicion and knowledge of the disease is of paramount importance as it has a wide range of presentation and variable course thus posing a diagnostic challenge. We present two cases of this rare disease in elderly females with distinct presentations although with similar and characteristic radiological findings along with a brief review of literature of the disease.
Castellana G, Castellana G, Gentile M, et al. Pulmonary alveolar microlithiasis: Review of the 1022 cases reported worldwide. Eur Respir Rev 2015;24:607-20.
DOI: https://doi.org/10.1183/16000617.0036-2015
Tendolkar M. An “Orphan” in search of a treatment: Pulmonary alveolar microlithiasis. Lung India 2019;36:553.
DOI: https://doi.org/10.4103/lungindia.lungindia_437_19
Viswananthan R. Pulmonary alveolar microlithiasis. Thorax 1962;17:251-6.
DOI: https://doi.org/10.1136/thx.17.3.251
Harbitz F. Extensive calcification of the lungs as a distinct disease. Arch Intern Med (Chic) 1918;XXI:139-46.
DOI: https://doi.org/10.1001/archinte.1918.00090070150012
Saito A, McCormack FX. Pulmonary Alveolar Microlithiasis. Clin Chest Med. 2016;37:441-8.
DOI: https://doi.org/10.1016/j.ccm.2016.04.007
Castellana G, Gentile M, Castellana R, et al. Pulmonary alveolar microlithiasis: clinical features, evolution of the phenotype, and review of the literature. Am J Med Genet 2002;111:220–4.
DOI: https://doi.org/10.1002/ajmg.10530
Tachibana T, Hagiwara K, Johkoh T. Pulmonary alveolar microlithiasis: Review and management. Curr Opin Pulm Med 2009;15:486-90.
DOI: https://doi.org/10.1097/MCP.0b013e32832d03bb
Castellana G, Carone D, Castellana M. Microlithiasis of seminal vesicles and severe oligoasthenospermia in pulmonary alveolar microlithiasis (PAM): report of an unusual sporadic case. Int J Fertil Steril 2015; 9:137-40.
Balikian JP, Fuleihan FJ, Nucho CN. Pulmonary alveolar microlithiasis. Report of five cases with special reference to roentgen manifestations. Am J Roentgenol Radium Ther Nucl Med 1968;103:509-18.
DOI: https://doi.org/10.2214/ajr.103.3.509
Felson B. Thoracic calcifications. Dis Chest 1969;56:330-43.
DOI: https://doi.org/10.1378/chest.56.4.330
Cluzel P, Grenier P, Bernadac P, et al. Pulmonary alveolar microlithiasis: Ct findings. J Comput Assist Tomog. 1991;15:938-42.
DOI: https://doi.org/10.1097/00004728-199111000-00006
Pracyk JB, Simonson SG, Young SL, et al. Composition of lung lavage in pulmonary alveolar microlithiasis. Respiration 1996;63:254-60.
DOI: https://doi.org/10.1159/000196556
Ganesan N, Ambroise MM, Ramdas A, et al. Pulmonary alveolar microlithiasis: an interesting case report with systematic review of Indian literature. Front Med 2015;9:229-38.
DOI: https://doi.org/10.1007/s11684-015-0394-y
Belém LC, Zanetti G, Souza AS, et al. Metastatic pulmonary calcification: State-of-the-art review focused on imaging findings. Respir Med 2014;108:668-76.
DOI: https://doi.org/10.1016/j.rmed.2014.01.012
Ozcelik U, Yalcin E, Arıyurek M, et al. Long-term results of disodium etidronate treatment in pulmonary alveolar microlithiasis. Pediatr Pulmonol 2010;45:514-7.
DOI: https://doi.org/10.1002/ppul.21209
Stamatis G, Zerkowski H, Doetsch N, et al. Sequential bilateral lung transplantation for pulmonary alveolar microlithiasis. Ann Thorac Surg 1993;56:972-5.
DOI: https://doi.org/10.1016/0003-4975(93)90370-W
Jindal A, Rahulan V, Balasubramani G, et al. Pulmonary alveolar microlithiasis: A rare disease treated with lung transplantation, first case from India. Lung India 2019;36:546.
DOI: https://doi.org/10.4103/lungindia.lungindia_50_19
How to Cite
Mittal, Richa, Rohit Kumar, Juvva Kishan Srikanth, Siddharth Raj Yadav, Ravi Chandak, and Shibdas Chakrabarti. 2021. “Pulmonary Alveolar Microlithiasis: Blizzard of Lung”. Monaldi Archives for Chest Disease 91 (4). https://doi.org/10.4081/monaldi.2021.1709.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Luigi Pinto, Pietro Schino, Michele Bitetto, Ersilia Tedeschi, Michele Maiellari, Giancarlo De Leo, Elena Ludovico, Giovanni Larizza, Franco Mastroianni, Fibrotic outcomes from SARS-CoV-2 virus interstitial pneumonia , Monaldi Archives for Chest Disease: Early Access
- Sandra Eugênia Coutinho, Raimunda Sinthia Lima de Braga, André Külzer Santos, Joanna Scopel Velho, Denise Rossato Silva, Smoking cessation among tuberculosis patients during the coronavirus disease-2019 pandemic , Monaldi Archives for Chest Disease: Early Access
- Shoaib Ahmad, Uzzam Ahmed Khawaja, Syed Meeran Haider, Wafaa Binti Mowlabaccus, Anmol Mohan, Asad Ansari, Muhammad Ahmad, Tulika Garg, Hafsa Ahmed, Shkaib Ahmad, Mohammad Yasir Essar, Javier Perez-Fernandez, George D. Yatzkan, Assessing the knowledge, attitude, and practice measures against tuberculosis in patients in ambulatory department facilities in Pakistan: a cross-sectional analysis , Monaldi Archives for Chest Disease: Vol. 94 No. 1 (2024)
- Erim Bešić, Davorka Muršić, Tajana Jalušić Glunčić, Jelena Ostojić, Sanda Škrinjarić-Cincar, Martina Dokoza, Nataša Karamarković Lazarušić, Miroslav Samaržija, Andrea Vukić Dugac, Prediction of spirometry outcome in Croatian patients with chronic obstructive pulmonary disease , Monaldi Archives for Chest Disease: Early Access
- Jinish Doshi, Kunal Deokar, Priyanka Gaikwad, Novel tuberculosis skin tests for detecting latent tuberculosis infection , Monaldi Archives for Chest Disease: Early Access
- Sabah Ahmed Hussein, Hari Kishan Gonuguntla, Sarabon Tahura, Belgundi Preeti, Vishnu G Krishnan, Nitesh Gupta, Ahmed Al-Halfawy, Felix J Herth, Flexible bronchoscopy-assisted removal of aspirated scarf pins from the tracheobronchial tree: the experience of 146 subjects , Monaldi Archives for Chest Disease: Early Access
- Moncef Maiouak, Vanessa Garcia-Larsen, Soumaya Benmaamar, Ibtissam El Harch, Mohamed El Biaz, Chakib Nejjari, Mohammed Chakib Benjelloun, Karima El Rhazi, Factors influencing health-related quality of life in patients with chronic obstructive pulmonary disease: insights from the Burden of Obstructive Lung Disease Study in Fez, Morocco , Monaldi Archives for Chest Disease: Early Access
- Tochukwu Adizie, Lauren Dolan, Aqusa Zahid, Ahmed Fahim, Assessing disease activity in scleroderma-related interstitial lung disease: a review and practical guide to management , Monaldi Archives for Chest Disease: Early Access
- Vidushi Rathi, Pranav Ish, Comments on “Mucoepidermoid carcinoma of the bronchus: a rare early diagnosis” , Monaldi Archives for Chest Disease: Early Access
- Paola Maria Medusa , Marina Gilli, Luca Notizia, Raffaella Pagliaro, Nicola Carro, Alessandro Moriello, Vito D'Agnano, Andrea Bianco, Fabio Perrotta, Fabiana Vitiello, Complete response to pembrolizumab as a single agent in a patient with stage III NSCLC with high PD-L1 expression: a case report , Monaldi Archives for Chest Disease: Vol. 93 No. 4 (2023)
<< < 35 36 37 38 39 40 41 42 43 44 > >>
You may also start an advanced similarity search for this article.
