https://doi.org/10.4081/monaldi.2021.1709
Pulmonary alveolar microlithiasis: Blizzard of lung
Submitted: December 1, 2020
Accepted: April 22, 2021
Published: June 10, 2021
Accepted: April 22, 2021
Abstract Views: 1539
PDF: 671
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Pulmonary alveolar microlithiasis (PAM) is a rare inherited disorder in which patients present with either nonspecific signs and symptoms or are asymptomatic. Clinical-radiological dissociation is a commonly seen feature of the disease. Majority of cases are diagnosed in second and third decade of life, although presentation in paediatric and elderly population is also reported. Pathognomonic radiological findings, with normal calcium and phosphate levels can confirm the diagnosis without the need of further investigations in large number of cases. A high index of suspicion and knowledge of the disease is of paramount importance as it has a wide range of presentation and variable course thus posing a diagnostic challenge. We present two cases of this rare disease in elderly females with distinct presentations although with similar and characteristic radiological findings along with a brief review of literature of the disease.
Castellana G, Castellana G, Gentile M, et al. Pulmonary alveolar microlithiasis: Review of the 1022 cases reported worldwide. Eur Respir Rev 2015;24:607-20.
DOI: https://doi.org/10.1183/16000617.0036-2015
Tendolkar M. An “Orphan” in search of a treatment: Pulmonary alveolar microlithiasis. Lung India 2019;36:553.
DOI: https://doi.org/10.4103/lungindia.lungindia_437_19
Viswananthan R. Pulmonary alveolar microlithiasis. Thorax 1962;17:251-6.
DOI: https://doi.org/10.1136/thx.17.3.251
Harbitz F. Extensive calcification of the lungs as a distinct disease. Arch Intern Med (Chic) 1918;XXI:139-46.
DOI: https://doi.org/10.1001/archinte.1918.00090070150012
Saito A, McCormack FX. Pulmonary Alveolar Microlithiasis. Clin Chest Med. 2016;37:441-8.
DOI: https://doi.org/10.1016/j.ccm.2016.04.007
Castellana G, Gentile M, Castellana R, et al. Pulmonary alveolar microlithiasis: clinical features, evolution of the phenotype, and review of the literature. Am J Med Genet 2002;111:220–4.
DOI: https://doi.org/10.1002/ajmg.10530
Tachibana T, Hagiwara K, Johkoh T. Pulmonary alveolar microlithiasis: Review and management. Curr Opin Pulm Med 2009;15:486-90.
DOI: https://doi.org/10.1097/MCP.0b013e32832d03bb
Castellana G, Carone D, Castellana M. Microlithiasis of seminal vesicles and severe oligoasthenospermia in pulmonary alveolar microlithiasis (PAM): report of an unusual sporadic case. Int J Fertil Steril 2015; 9:137-40.
Balikian JP, Fuleihan FJ, Nucho CN. Pulmonary alveolar microlithiasis. Report of five cases with special reference to roentgen manifestations. Am J Roentgenol Radium Ther Nucl Med 1968;103:509-18.
DOI: https://doi.org/10.2214/ajr.103.3.509
Felson B. Thoracic calcifications. Dis Chest 1969;56:330-43.
DOI: https://doi.org/10.1378/chest.56.4.330
Cluzel P, Grenier P, Bernadac P, et al. Pulmonary alveolar microlithiasis: Ct findings. J Comput Assist Tomog. 1991;15:938-42.
DOI: https://doi.org/10.1097/00004728-199111000-00006
Pracyk JB, Simonson SG, Young SL, et al. Composition of lung lavage in pulmonary alveolar microlithiasis. Respiration 1996;63:254-60.
DOI: https://doi.org/10.1159/000196556
Ganesan N, Ambroise MM, Ramdas A, et al. Pulmonary alveolar microlithiasis: an interesting case report with systematic review of Indian literature. Front Med 2015;9:229-38.
DOI: https://doi.org/10.1007/s11684-015-0394-y
Belém LC, Zanetti G, Souza AS, et al. Metastatic pulmonary calcification: State-of-the-art review focused on imaging findings. Respir Med 2014;108:668-76.
DOI: https://doi.org/10.1016/j.rmed.2014.01.012
Ozcelik U, Yalcin E, Arıyurek M, et al. Long-term results of disodium etidronate treatment in pulmonary alveolar microlithiasis. Pediatr Pulmonol 2010;45:514-7.
DOI: https://doi.org/10.1002/ppul.21209
Stamatis G, Zerkowski H, Doetsch N, et al. Sequential bilateral lung transplantation for pulmonary alveolar microlithiasis. Ann Thorac Surg 1993;56:972-5.
DOI: https://doi.org/10.1016/0003-4975(93)90370-W
Jindal A, Rahulan V, Balasubramani G, et al. Pulmonary alveolar microlithiasis: A rare disease treated with lung transplantation, first case from India. Lung India 2019;36:546.
DOI: https://doi.org/10.4103/lungindia.lungindia_50_19
How to Cite
Mittal, Richa, Rohit Kumar, Juvva Kishan Srikanth, Siddharth Raj Yadav, Ravi Chandak, and Shibdas Chakrabarti. 2021. “Pulmonary Alveolar Microlithiasis: Blizzard of Lung”. Monaldi Archives for Chest Disease 91 (4). https://doi.org/10.4081/monaldi.2021.1709.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Lucrezia De Michele, Paola Pierucci, Guido Giovannetti, Arnaldo Scardapane, Carlo D'agostino, Giovanna Elisiana Carpagnano, Authors’ response to the Letter to the Editor regarding: Post severe COVID-19 infection lung damages study. The experience of early three months multidisciplinary follow-up , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Rajesh Venkataram, Vijith Shetty, Kishan Prasad, Sonam Kille, Teerthanath Srinivas, Anirban Chakraborty, Detection of clinically-relevant EGFR variations in de novo small cell lung carcinoma by droplet digital PCR , Monaldi Archives for Chest Disease: Vol. 93 No. 2 (2023)
- Sunil Mahavar, Princy Tyagi, Abhishek Agrawal, Sudhir Bhandari, Subrata Banerjee, Raman Sharma, Prakash Keshwani, Clinical and epidemiological profile of Indian COVID-19 patients from Jaipur: a descriptive study , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Konstantinos Kapriniotis, Angelina Bania, Savvas Lampridis, Georgios Geropoulos, Sofoklis Mitsos, Fleur Monk, David A. Moore, Nikolaos Panagiotopoulos, Metastatic mandibular ameloblastoma of the lung ten years after primary resection: A rare case report , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Sergio C. Conte, Giulia Spagnol, Marco Biolo, Marco Confalonieri, A retrospective study of endobronchial ultrasound transbronchial needle aspiration versus conventional transbronchial needle aspiration in diagnosis/staging of hilar/mediastinal lymph node in lung cancer: Which role in clinical practice? , Monaldi Archives for Chest Disease: Vol. 89 No. 1 (2019)
- Carlo Uran, Through the heart and beyond: a review on ranolazine , Monaldi Archives for Chest Disease: Vol. 92 No. 1 (2022)
- Kartik Deshmukh, Arjun Khanna, Single inhaler triple therapy in COPD – all that glitters is not gold , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Cuneyt Tetikkurt, Nurbanu Inci, Hail Yanardag, Diagnostic utility of PET/CT in a patient with miliary tuberculosis , Monaldi Archives for Chest Disease: Vol. 89 No. 2 (2019)
- Laura Bertacchini, Mara Paneroni, Laura Comini, Simonetta Scalvini, Michele Vitacca, Recovering of oxygenation, physical function and disability in patients with Covid-19 , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Roberto Torchio, Alessandra Mazzucco, Marco Guglielmo, Roberto Giardino, Claudio Ciacco, Francesco Ardissone, Minute ventilation to carbon dioxide output (V’E/V’CO2 slope) is the strongest death predictor before larger lung resections , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
<< < 49 50 51 52 53 54 55 56 57 58 > >>
You may also start an advanced similarity search for this article.
