https://doi.org/10.4081/monaldi.2021.1721
Lipid-lowering therapy in high cardiovascular risk patients during COVID-19 pandemic: keep focused on the target
Submitted: December 5, 2020
Accepted: January 8, 2021
Published: May 4, 2021
Accepted: January 8, 2021
Abstract Views: 1114
PDF: 637
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
To the Editor
COVID-19 (COrona VIrus Disease) patients with cardiovascular (CV) disease, multiple CV risk factors or comorbidities (i.e., arterial hypertension and diabetes) were shown to be more prone to a worse prognosis. SARS-CoV-2 is a still unknown enemy and the role of concomitant cardiovascular therapies has been controversial in the early stages, particularly with regard to Angiotensin-Converting Enzyme inhibitors...
Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020;323:1239-42.
DOI: https://doi.org/10.1001/jama.2020.2648
Fedson DS. Treating influenza with statins and other immunomodulatory agents. Antiviral Res 2013;99:417–35.
DOI: https://doi.org/10.1016/j.antiviral.2013.06.018
Frost FJ, Petersen H, Tollestrup K, Skipper B. Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins. Chest 2007;131:1006-12.
DOI: https://doi.org/10.1378/chest.06-1997
Douglas I, Evans S, Smeeth L. Effect of statin treatment on short term mortality after pneumonia episode: cohort study. BMJ 2011;342:d1642.
DOI: https://doi.org/10.1136/bmj.d1642
Shrivastava-Ranjan P, Flint M, Bergeron É, et al. Statins suppress Ebola virus infectivity by interfering with glycoprotein processing. mBio 2018;9:e00660-18.
DOI: https://doi.org/10.1128/mBio.00660-18
Yuan S. Statins may decrease the fatality rate of middle east respiratory syndrome infection. mBio 2015;6:e01120.
DOI: https://doi.org/10.1128/mBio.01120-15
Gupta A, Madhavan M V, Poterucha TJ, et al. Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19. Res Sq 2020; rs.3.rs-56210. Preprint
DOI: https://doi.org/10.21203/rs.3.rs-56210/v1
Fan Y, Guo T, Yan F, et al. Association of statin use with the in-hospital outcomes of 2019-coronavirus disease patients: A retrospective study. Front Med (Lausanne) 2020;7:584870.
DOI: https://doi.org/10.3389/fmed.2020.584870
Zhang X-J, Qin J-J, Cheng X, et al. In-hospital use of statins is associated with a reduced risk of mortality among individuals with COVID-19. Cell Metab 2020;32:176-87.e4.
DOI: https://doi.org/10.1016/j.cmet.2020.06.015
Saeed O, Castagna F, Agalliu I, et al. Statin use and inâ€hospital mortality in diabetics with COVIDâ€19. J Am Heart Assoc 2020;9:e018475.
DOI: https://doi.org/10.1161/JAHA.120.018475
Song SL, Hays SB, Panton CE, et al. Statin use is associated with decreased risk of invasive mechanical ventilation in COVID-19 patients: A preliminary study. Pathogens 2020;9:759.
DOI: https://doi.org/10.3390/pathogens9090759
Daniels LB, Sitapati AM, Zhang J, et al. Relation of statin use prior to admission to severity and recovery among COVID-19 inpatients. Am J Cardiol 2020;136:149-55.
DOI: https://doi.org/10.1016/j.amjcard.2020.09.012
Butt JH, Gerds TA, Schou M, et al. Association between statin use and outcomes in patients with coronavirus disease 2019 (COVID-19): a nationwide cohort study. BMJ Open 2020;10:e044421.
DOI: https://doi.org/10.1136/bmjopen-2020-044421
Cariou B, Goronflot T, Rimbert A, et al. Routine use of statins and increased COVID-19 related mortality in inpatients with type 2 diabetes: Results from the CORONADO study. Diabetes Metab 202;101202.
DOI: https://doi.org/10.1016/j.diabet.2020.10.001
Kow CS, Hasan SS. Meta-analysis of effect of statins in patients with COVID-19. Am J Cardiol 2020;134:153–5.
DOI: https://doi.org/10.1016/j.amjcard.2020.08.004
Hariyanto TI, Kurniawan A. Statin therapy did not improve the in-hospital outcome of coronavirus disease 2019 (COVID-19) infection. Diabetes Metab Syndr Clin Res Rev 2020;14:1613–5.
DOI: https://doi.org/10.1016/j.dsx.2020.08.023
Scheen AJ. Statins and clinical outcomes with COVID-19: Meta-analyses of observational studies. Diabetes Metab 2020;47:101220.
DOI: https://doi.org/10.1016/j.diabet.2020.101220
Bikdeli B, Talasaz AH, Rashidi F, et al. Intermediate versus standard-dose prophylactic anticoagulation and statin therapy versus placebo in critically-ill patients with COVID-19: Rationale and design of the INSPIRATION/INSPIRATION-S studies. Thromb Res 2020;196:382–94.
DOI: https://doi.org/10.1016/j.thromres.2020.09.027
Cesaro A, Bianconi V, Gragnano F, et al. Beyond cholesterol metabolism: The pleiotropic effects of proprotein convertase subtilisin/kexin type 9 (PCSK9). Genetics, mutations, expression, and perspective for longâ€term inhibition. Biofactors 2020;46:367-80.
DOI: https://doi.org/10.1002/biof.1619
Iqbal Z, Ho JH, Adam S, et al. Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK. Atherosclerosis 2020;313:126-36.
DOI: https://doi.org/10.1016/j.atherosclerosis.2020.09.008
Mureddu GF, Ambrosetti M, Venturini E, et al. Cardiac rehabilitation activities during the COVID-19 pandemic in Italy. Position Paper of the AICPR (Italian Association of Clinical Cardiology, Prevention and Rehabilitation). Monaldi Arch Chest Dis 2020;90:1439.
DOI: https://doi.org/10.4081/monaldi.2020.1439
Gragnano F, Natale F, Concilio C, et al. Adherence to proprotein convertase subtilisin/kexin 9 inhibitors in high cardiovascular risk patients: An Italian single-center experience. J Cardiovasc Med 2018;19:75–7.
DOI: https://doi.org/10.2459/JCM.0000000000000611
Cesaro A, Gragnano F, Fimiani F, et al. Impact of PCSK9 inhibitors on the quality of life of patients at high cardiovascular risk. Eur J Prev Cardiol 2020;27:556-8.
DOI: https://doi.org/10.1177/2047487319839179
Kotseva K, De Backer G, De Bacquer D, et al. Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry. Eur J Prev Cardiol 2019;26:824-35.
DOI: https://doi.org/10.1177/2047487318825350
How to Cite
Cesaro, Arturo, Carmine Riccio, and Paolo Calabrò. 2021. “Lipid-Lowering Therapy in High Cardiovascular Risk Patients During COVID-19 Pandemic: Keep Focused on the Target”. Monaldi Archives for Chest Disease 91 (2). https://doi.org/10.4081/monaldi.2021.1721.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Roberto F.E. Pedretti, Francesco Fattirolli, Raffaele Griffo, Marco Ambrosetti, Elisabetta Angelino, Silvia Brazzo, Ugo Corrà , Nicolò Dasseni, Pompilio Faggiano, Giuseppe Favretto, Oreste Febo, Marina Ferrari, Francesco Giallauria, Cesare Greco, Manuela Iannucci, Maria Teresa La Rovere, Mario Mallardo, Antonio Mazza, Massimo Piepoli, Carmine Riccio, Simonetta Scalvini, Luigi Tavazzi, Pier Luigi Temporelli, Gian Francesco Mureddu, Cardiac Prevention and Rehabilitation “3.0â€: From acute to chronic phase. Position Paper of the ltalian Association for Cardiovascular Prevention and Rehabilitation (GICR-IACPR) , Monaldi Archives for Chest Disease: Vol. 88 No. 3 (2018)
- Gianfranco Beghi, Antonio De Tanti, Paolo Serafini, Chiara Bertolino, Antonietta Celentano, Graziella Taormina, Monitoring of hospital acquired pneumonia in patients with severe brain injury on first access to intensive neurological rehabilitation: First year of observation , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Marinella Sommaruga, Elisabetta Angelino, Paola Della Porta, Mara Abatello, Giacomo Baiardo, Gianluigi Balestroni, Ornella Bettinardi, Edward Callus, Chiara Ciracì, Ombretta Omodeo, Claudia Rizza, Paolo Michielin, Marco Ambrosetti, Raffaele Griffo, Roberto F.E. Pedretti, Antonia Pierobon, Best practice in psychological activities in cardiovascular prevention and rehabilitation: Position Paper , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- Floriana Caccamo, Simone Saltini, Enrico Carella, Roberto Carlon, Cristina Marogna, Vito Sava, The measure of effectiveness of a short-term 2-week intensive Cardiac Rehabilitation program in decreasing levels of anxiety and depression , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Marco Ambrosetti, Simona Sarzi Braga, Franco Giada, Roberto F.E. Pedretti, Exercise-based cardiac rehabilitation in cardiac resynchronization therapy recipients: A primer for practicing clinicians , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- Francesco Giallauria, Rosa Lucci, Francesco Pilerci, Anna De Lorenzo, Athanasio Manakos, Marianna Psaroudaki, Mariantonietta D’Agostino, Alessandra Vitelli, Luigi Maresca, Domenico Del Forno, Carlo Vigorito, Efficacy of Telecardiology in improving the results of Cardiac Rehabilitation after acute myocardial infarction , Monaldi Archives for Chest Disease: Vol. 66 No. 1 (2006): Cardiac series
- Francesco Giallauria, Lucrezia Piccioli, Giuseppe Vitale, Filippo M. Sarullo, Exercise training in patients with chronic heart failure: A new challenge for Cardiac Rehabilitation Community , Monaldi Archives for Chest Disease: Vol. 88 No. 3 (2018)
- Raffaele Griffo, Francesco Fattirolli, Pier Luigi Temporelli, Roberto Tramarin, Italian survey on CArdiac RehabilitatiOn and Secondary prevention after cardiac revascularization: ICAROS study. A survey from the italian cardiac rehabilitation network: rationale and design , Monaldi Archives for Chest Disease: Vol. 70 No. 3 (2008): Cardiac series
- Claudio F. Donner, Sandro Amaducci, Elena Bacci, Sandra Baldacci, Maria L. Bartoli, Gianfranco M. Beghi, Alida Benfante, Sara Brighindi, Lucio Casali, Daniela Castiglia, Mario Cazzola, Alessandro Celi, Silvana Cianchetti, Giorgio Colombo, Claudia Crimi, Federico L. Dente, Giuseppe Di Maria, Annalisa Di Maria, Manuela Latorre, Federico Lavorini, Sara Maio, Claudia Mannini, Riccardo Messina, Pier Luigi Paggiaro, Patrizia Pignatti, David Price, Nicola Scichilone, Marzia Simoni, Antonio Spanevello, Martina Stagno d’Alcontres, Shawna Tan, Roberto Torchio, Giovanni Viegi, Dina Visca, Emiel F.M. Wouters, Shaylynn Yu Hui Xin, Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Massimiliano Polastri, Lara Pisani, Andrea Dell'Amore, Stefano Nava, Revolving door respiratory patients: A rehabilitative perspective , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
You may also start an advanced similarity search for this article.
