https://doi.org/10.4081/monaldi.2021.1739
Bleeding events in COVID-19: the other side of the coin?
Submitted: December 15, 2020
Accepted: February 28, 2021
Published: April 1, 2021
Accepted: February 28, 2021
Abstract Views: 3031
PDF: 505
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
We present three cases of patients affected by severe SARS-CoV-2-related pneumonia treated with a low molecular weight heparin for prevention or treatment of pulmonary embolism, who presented a major bleed, in particular an ileopsoas haematoma that caused severe anaemia; in one case it was fatal. In the recent outbreak of novel coronavirus infection, significantly abnormal coagulation parameters in SARS-CoV-2 infection occur very often, but complications in the opposite direction such as bleeding diathesis are very rare. In these cases, there are different levels of gravity: for one patient the major bleed required the anticoagulant therapy to be stopped until bleeding stabilized, one patient needed interventional radiology and one patient died.
Richmann DD, Whitley RJ, Hayden FG, eds. Clinical virology, 4th ed. Washington: ASM Press; 2016.
DOI: https://doi.org/10.1128/9781555819439
Tang N, Li D, Wang X, et al. Abnormal coagulation parameters are associated with poor prognosis in patient with novel coronavirus pneumonia. J Thromb Haemost 2020;18:844-7.
DOI: https://doi.org/10.1111/jth.14768
Wang T, Chen R, Liu C, et al. Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19. Lancet Haematol 2020;7:e362-3.
DOI: https://doi.org/10.1016/S2352-3026(20)30109-5
Marquardt G, Barduzal Angles S, Leheta F, et al. Spontaneous haematoma of the iliac psoas muscle: a case report and review of the literature. Arch Orthop Trauma Surg 2002;122:109-11.
DOI: https://doi.org/10.1007/s004020100310
Ciceri F, Beretta L, Scandroglio AM. Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis. Crit Care Resusc 2020;22:95-7.
Al-Samkari H, Karp Leaf RS, Dzik WH, et al. COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection. Blood 2020;136:489–500.
DOI: https://doi.org/10.1182/blood.2020006520
Taylor FB Jr, Toh CH, Hoots WK, et al. Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost 2001;86:1327-30.
DOI: https://doi.org/10.1055/s-0037-1616068
Li Y, Zhao K, Wei H, et al. Dynamic relationship between D-dimer and COVID-19 severity. Br J Haematol 2020;190:e24-7.
DOI: https://doi.org/10.1111/bjh.16811
Palumbo D, Guazzarotti G, De Cobelli F. Spontaneous major hemorrhage in COVID-19 patients: Another brick in the wall of SARS-CoV-2-associated coagulation disorders? J Vasc Interv Radiol 2020;31:1494-6.
DOI: https://doi.org/10.1016/j.jvir.2020.06.010
Conti CB, Henchi S, Coppeta GP, et al. Bleeding in COVID-19 severe pneumonia: The other side of abnormal coagulation pattern? Eur J Intern Med 2020;77:147-9.
DOI: https://doi.org/10.1016/j.ejim.2020.05.002
How to Cite
Coppola, Antonietta, Anna Annunziata, Maria Rosaria Gioia, and Giuseppe Fiorentino. 2021. “Bleeding Events in COVID-19: The Other Side of the Coin?”. Monaldi Archives for Chest Disease 91 (3). https://doi.org/10.4081/monaldi.2021.1739.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Dario Amore, Emanuele Muto, Umberto Caterino, Dino Casazza, Alessandro Saglia, Pasquale Imitazione, Carlo Curcio, Anomalous segmental pulmonary vein: additional V6 behind the bronchus intermedius draining into the superior pulmonary vein , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Aiswarya M Nair, Sowmya Gopalan, Vaasanthi Rajendran, Priyadarshini Varadaraj , Lakshmi Marappa , Viswanathan Pandurangan , Sudha Madhavan, Rajkumar Mani , Emmanuel Bhaskar , Role of secondary sepsis in COVID-19 mortality: Observations on patients with preexisting diabetes mellitus and newly diagnosed hyperglycemia , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Ravindra Nath, Neeraj Kumar Gupta, Amandeep Jaswal, Sparsh Gupta, Navjot Kaur, Santvana Kohli, Anirudh saxena, Pranav Ish, Rohit Kumar, Poornima Tiwari, Mukesh Kumar, Jugal Kishore, Geeta Yadav, Fellisha Marwein, Nitesh Gupta, Mortality among adult hospitalized patients during the first wave and second wave of COVID-19 pandemic at a tertiary care center in India , Monaldi Archives for Chest Disease: Vol. 92 No. 2 (2022)
- Zehra Naseem, Muhammad Mussab Khakwani, Maaha Ayub, Ahmed Ayaz, Bushra Jamil, Ainan Arshad, SARS-CoV-2 induced coagulopathy and potential role of anticoagulation: Scoping review of literature , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
- Tobin P. Mangel, Brendan P. Madden, Acute tracheal tear – A potential cause of spontaneous pneumomediastinum in patients with COVID-19 , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Laura Bertacchini, Mara Paneroni, Laura Comini, Simonetta Scalvini, Michele Vitacca, Recovering of oxygenation, physical function and disability in patients with Covid-19 , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- C. Gurioli, G.L. Casoni, C. Gurioli, S. Tomassetti, M. Romagnoli, C. Ravaglia, V. Poletti, Endobronchial ultrasound in Dieulafoy's disease of the bronchus: an additional application of EBUS , Monaldi Archives for Chest Disease: Vol. 73 No. 4 (2010): Pulmonary series
You may also start an advanced similarity search for this article.
