https://doi.org/10.4081/monaldi.2021.1781

Primary Hodgkin lymphoma of the lung arising with hemoptysis and pulmonary consolidation: a case report

Vol. 91 No. 4 (2021)
Submitted: January 25, 2021
Accepted: May 7, 2021
Published: June 10, 2021
Lymphoma, Pulmonary Primary Extranodal classic Hodgkin Lymphoma, lung resection, haemoptysis
Abstract Views: 1297
PDF: 642
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Authors

Pietro Bertoglio
pieberto@hotmail.com
https://orcid.org/0000-0002-6267-0099
Division of Thoracic Surgery, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar (VR), Italy.
Ivan Lomangino
Division of Thoracic Surgery, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar (VR); Division of Thoracic Surgery, University Hospital of Padua, Italy.
Giulia Querzoli
https://orcid.org/0000-0002-6944-6508
Division of Pathological Anatomy, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar (VR), Italy.
Angela Bonalumi
Division of Hematology, University Hospital of Verona, Italy.
Giuseppe S. Bogina
https://orcid.org/0000-0002-0311-2708
Division of Pathological Anatomy, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar (VR), Italy.
Alberto C. Terzi
https://orcid.org/0000-0002-2272-0389
Division of Thoracic Surgery, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar (VR), Italy.

Classic Hodgkin lymphomas are neoplasms originating from lymphoid tissue. Primary extra-nodal classic Hodgkin lymphoma (PE-cHL) of the lung is rare. A 37-years-old Caucasian male was referred to our hospital for recurrent episodes of hemoptysis, cough and bronchitis. A computed tomography (CT) scan showed a massive left upper lung consolidation, which was positive at the positron emission tomography (PET) scan. After several inconclusive tests and no benefit from medical therapies, the patient underwent a left upper lobectomy; pathology report showed a classical type Hodgkin lymphoma with no lymph-nodes involvement. Four cycles of adjuvant chemotherapy were administered with no toxicity. At the last follow up 14 months after surgery, the patient is alive and free from disease. Primary extra-nodal classical Hodgkin lymphoma of the lung is a rare entity, but it should be considered as a differential diagnosis in young patients with pulmonary consolidation even without systemic symptoms.

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Scopus
Google Scholar
Europe PMC
Cooksley N, Judge DJ, Brown J. Primary pulmonary Hodkgin’s Lymphoma and a review of the literature since 2006. BMJ Case Rep 2014;2014:bcr2014204020. DOI: https://doi.org/10.1136/bcr-2014-204020
Rodriguez J, Tirabosco R, Pizzolitto S, et al. Hodgkin lymphoma presenting with exclusive or preponderant pulmonary involvement: a clinicopathologic study of 5 new cases. Ann Diagn Pathol 2006;10:83-8. DOI: https://doi.org/10.1016/j.anndiagpath.2005.07.014
Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol 2014;32:3059-68. DOI: https://doi.org/10.1200/JCO.2013.54.8800
Cavalli F, Stein H, Zucca E. Extranodal lymphomas pathology and management. Informa: London; 2008 DOI: https://doi.org/10.3109/9780203091753
Yang M, Ping L, Liu W, et al. Clinical characteristics and prognostic factors of primary extranodal classical Hodgkin lymphoma: a retrospective study. Hematology 2019;24:413-9. DOI: https://doi.org/10.1080/16078454.2019.1598678
Kumar R, Sidhu H, Mistry R, Shet T, Primary pulmonary Hodgkin's lymphoma: a rare pitfall in transthoracic fine needle aspiration cytology. Diagn Cytopathol 2008;36:666-9. DOI: https://doi.org/10.1002/dc.20872
O'Malley DP, Dogan A, Fedoriw Y, et al. American Registry of Pathology Expert Opinions: Immunohistochemical evaluation of classic Hodgkin lymphoma. Ann Diagn Pathol 2019;39:105-10. DOI: https://doi.org/10.1016/j.anndiagpath.2019.02.001
Muzzafar T, Wei EX, Lin P, et al. Flow cytometric immunophenotyping of anaplastic large cell lymphoma. Arch Pathol Lab Med 2009;133:49-56. DOI: https://doi.org/10.5858/133.1.49
Gulley ML, Glaser SL, Craig FE, et al., Guidelines for interpreting EBER in situ hybridization and LMP1 immunohistochemical tests for detecting Epstein-Barr virus in Hodgkin lymphoma. Am J Clin Pathol 2002;117:259-67. DOI: https://doi.org/10.1309/MMAU-0QYH-7BHA-W8C2

How to Cite

Bertoglio, Pietro, Ivan Lomangino, Giulia Querzoli, Angela Bonalumi, Giuseppe S. Bogina, and Alberto C. Terzi. 2021. “Primary Hodgkin Lymphoma of the Lung Arising With Hemoptysis and Pulmonary Consolidation: A Case Report”. Monaldi Archives for Chest Disease 91 (4). https://doi.org/10.4081/monaldi.2021.1781.
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