https://doi.org/10.4081/monaldi.2021.1808

Common anti-oxidant vitamin C as an anti-infective agent with remedial role on SARS-CoV-2 infection. An update

Vol. 91 No. 4 (2021)
Submitted: February 16, 2021
Accepted: May 26, 2021
Published: July 19, 2021
SARS-CoV-2 infection, Vitamin C, COVID-19 treatment
Abstract Views: 1789
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Authors

Christos Michailides
https://orcid.org/0000-0003-1712-9815
Department of Internal Medicine, University Hospital of Patras, Greece.
Dimitrios Velissaris
dvelissaris@upatras.gr
https://orcid.org/0000-0002-9319-323X
Department of Internal Medicine, University Hospital of Patras, Greece.

Coronavirus disease 2019 (COVID-19) has led to a worldwide multifaceted crisis. The medical world agonizes to contend with the problem, but a string of tested medications has been proven unavailing. Vitamin C is well described as a salutary antioxidant and some trials conclude that it may be a potential antiviral drug. In high doses, vitamin C can alternate crucial steps in the pathogenesis of sepsis and acute respiratory distress syndrome. This dynamic was the driving force behind trials around the world that tried immunonutrition as a weapon against clinical entities. We summarize the mechanisms of action of vitamin C and its role against infections and the current literature referring to the potential role of vitamin C in SARS-CoV-2 infection, also as a contingent treatment agent.

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How to Cite

Michailides, Christos, and Dimitrios Velissaris. 2021. “Common Anti-Oxidant Vitamin C As an Anti-Infective Agent With Remedial Role on SARS-CoV-2 Infection. An Update”. Monaldi Archives for Chest Disease 91 (4). https://doi.org/10.4081/monaldi.2021.1808.
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