https://doi.org/10.4081/monaldi.2021.1845
Diffuse alveolar haemorrhage and myocardial infarction: life-threatening effects from self-injected hyaluronic acid dermal filler
Submitted: March 13, 2021
Accepted: June 11, 2021
Published: July 22, 2021
Accepted: June 11, 2021
Abstract Views: 1281
PDF: 618
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Hyaluronic acid (HA) is a widely used dermal filler for soft tissue augmentation. We described a case of a 38-year-old transwoman who presented with sudden onset of severe respiratory distress following self-injection of HA dermal filler. She developed multiple episodes of pulmonary haemorrhage, and her chest X-ray showed diffuse ground-glass opacities consistent with diffuse alveolar haemorrhage (DAH). There were no relevant drugs or past medical histories. Anti-nuclear antibodies and rheumatoid factor were negative. Initially, the pulmonary haemorrhage episodes and ventilation requirement improved with systemic steroid, however she subsequently developed acute myocardial infarction with progressive clinical deterioration leading to death. To the best of our knowledge, this is the first HA-related DAH with myocardial infarction reported with a fatal outcome. This case highlights the importance of awareness and the necessity of having a high suspicion of DAH in patients with history of illicit HA dermal filler use.
Park TH, Seo SW, Kim JK, Chang CH. Clinical experience with hyaluronic acid-filler complications. J Plast Reconstr Aesthetic Surg 2011;64:892–6.
DOI: https://doi.org/10.1016/j.bjps.2011.01.008
Han SW, Park MJ, Lee SH. Hyaluronic acid-induced diffuse alveolar hemorrhage: unknown complication induced by a well-known injectable agent. Ann Transl Med 2019;7:13–13.
DOI: https://doi.org/10.21037/atm.2018.11.51
Basora JF, Fernandez R, Gonzalez M, Adorno J. A case of diffuse alveolar hemorrhage associated with hyaluronic acid dermal fillers. Am J Case Rep 2014;15:199–202.
DOI: https://doi.org/10.12659/AJCR.889803
Park MS. Diffuse alveolar hemorrhage. Tuberc Respir Dis (Seoul) 2013;74:151–62.
DOI: https://doi.org/10.4046/trd.2013.74.4.151
Crea F, Libby P. Acute coronary syndromes: The way forward from mechanisms to precision treatment. Circulation 2017;136:1155–66.
DOI: https://doi.org/10.1161/CIRCULATIONAHA.117.029870
Ben Gabr J, Kato H. A case of diffuse alveolar hemorrhage associated with high-titer of MPO-ANCA demonstrating cytoplasmic staining pattern. Case Rep Rheumatol 2019;2019:1–5.
DOI: https://doi.org/10.1155/2019/6074792
Hammoudeh F, Perwaiz MK, Patolia S, et al. Diffuse alveolar haemorrhage with ANCA associated vasculitis - review of the literature. Br J Med Pract 2011;4:16–20.
West S, Arulkumaran N, Ind PW, Pusey CD. Diffuse alveolar haemorrhage in ANCA-associated vasculitis. Intern Med 2013;52:5–13.
DOI: https://doi.org/10.2169/internalmedicine.52.8863
Delorenzi C. Complications of injectable fillers, Part 2: Vascular complications. Aesthetic Surg J 2014;34:584–600.
DOI: https://doi.org/10.1177/1090820X14525035
Szczepanek K, Kieda C, Cichy J. Differential binding of hyaluronan on the surface of tissue-specific endothelial cell lines. Acta Biochim Pol 2008;55:35–42.
DOI: https://doi.org/10.18388/abp.2008_3198
LeBoeuf RD, Gregg RR, Fuller GM, Weigel PH. Effects of hyaluronic acid and other glycosaminoglycans on fibrin polymer formation. Biochemistry 1987;26:6052–7.
DOI: https://doi.org/10.1021/bi00393a016
Barbucci R, Benvenuti M, Casolaro M, et al. Sulfated hyaluronic acid as heparin-like material: physicochemical and biological characterization. J Mater Sci Mater Med 1994;5:830–3.
DOI: https://doi.org/10.1007/BF00213143
Esposito AJ, Bhatraju PK, Stapleton RD, et al. Hyaluronic acid is associated with organ dysfunction in acute respiratory distress syndrome. Crit Care 2017;21:304.
DOI: https://doi.org/10.1186/s13054-017-1895-7
Herold S, Gabrielli NM, Vadász I. Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 2013;305:L665-81.
DOI: https://doi.org/10.1152/ajplung.00232.2013
How to Cite
Che Ani, Amira Aishah, Sakinah Mohd Akhir, Winnie Chiang Li-Xue, Nur Zurairah Shahidan, and Azman Abd Hamid. 2021. “Diffuse Alveolar Haemorrhage and Myocardial Infarction: Life-Threatening Effects from Self-Injected Hyaluronic Acid Dermal Filler”. Monaldi Archives for Chest Disease 91 (4). https://doi.org/10.4081/monaldi.2021.1845.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Gian Francesco Mureddu, Pompilio Faggiano, Francesco Fattirolli, Preoperative evaluation before non cardiac surgery in subjects older than 65 years , Monaldi Archives for Chest Disease: Vol. 82 No. 1 (2014): Cardiac series
- D. Samolski, A. Antón, M. Mayos, M. Subirana, R. Güell, Primary alveolar hypoventilation and XXXXY chromosopathy , Monaldi Archives for Chest Disease: Vol. 65 No. 3 (2006): Pulmonary series
- Chiara Pedone, Stefano Urbinati, Maria Giovanna Pallotti, Giuseppe Pinelli, Obesity and cardiovascular disease: expected and unexpected relationship , Monaldi Archives for Chest Disease: Vol. 64 No. 1 (2005): Cardiac series
- Nicola Cosentino, Jeness Campodonico, Valentina Milazzo, Katia Celentano, Marco Moltrasio, Pompilio Faggiano, Giancarlo Marenzi, Extended dual antiplatelet therapy after acute myocardial infarction. Current evidence and future perspectives , Monaldi Archives for Chest Disease: Vol. 89 No. 2 (2019)
- E. Nardecchia, L. Perfetti, M. Castiglioni, D. Di Natale, A. Imperatori, N. Rotolo, Bullous lung disease and neurofibromatosis type-1 , Monaldi Archives for Chest Disease: Vol. 77 No. 2 (2012): Pulmonary series
- Commento bibliografico di Domenico Del Forno e Valentina Battimiello, Job strain predicts recurrent events after a first acute myocardial infarction: The Stockholm Heart Epidemiology Program , Monaldi Archives for Chest Disease: Vol. 74 No. 1 (2010): Cardiac series
- Domenico Sirico, Andrea Salzano, Dario Celentani, Michele Arcopinto, Alberto Maria Marra, Emanuele Bobbio, Angelo Russo, Francesco Giallauria, Carlo Vigorito, Anti remodeling therapy: new strategies and future perspective in post-ischemic heart failure: Part I , Monaldi Archives for Chest Disease: Vol. 82 No. 4 (2014): Cardiac series
- Federica Ilardi, Fabio Magliulo, Giuseppe Gargiulo, Gabriele Giacomo Schiattarella, Giuseppe Carotenuto, Federica Serino, Marco Ferrone, Emanuele Visco, Fernando Scudiero, Andreina Carbone, Cinzia Perrino, Bruno Trimarco, Giovanni Esposito, Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications , Monaldi Archives for Chest Disease: Vol. 76 No. 4 (2011): Cardiac series
- M. Messina, N. Scichilone, F. Guddo, V. Bellia, Rapidly progressive organising pneumonia associated with cytomegalovirus infection in a patient with psoriasis , Monaldi Archives for Chest Disease: Vol. 67 No. 3 (2007): Pulmonary series
- Vincenzo Capuano, Norman Lamaida, Sergio Torre, Ernesto Capuano, Maria Immacolata Borrelli, Eduardo Capuano, Maria Maddalena Clarizia, Rocco Capuano, Carmela De Rosa, Ten year cardio-cerebro-vascular mortality and morbidity in a Southern Italy cohort: the VIP Project data , Monaldi Archives for Chest Disease: Vol. 80 No. 1 (2013): Cardiac series
<< < 20 21 22 23 24 25 26 27 28 29 > >>
You may also start an advanced similarity search for this article.
