https://doi.org/10.4081/monaldi.2021.1878

Platypnea orthodeoxia syndrome in a patient with patent foramen ovale and normal atrial pressure. Case report and presentation of underlying pathophysiological mechanisms

Vol. 92 No. 1 (2022)
Submitted: April 5, 2021
Accepted: June 13, 2021
Published: September 28, 2021
Patent foramen ovale, platypnea orthodeoxia syndrome, hypoxemia
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Authors

Fotios Sampsonas
fsampsonas@gmail.com
https://orcid.org/0000-0002-7796-2959
Respiratory Department, School of Medicine, Patras University Hospital, Greece.
Matthaios Katsaras
Respiratory Department, School of Medicine, Patras University Hospital, Greece.
Ourania Papaioannou
https://orcid.org/0000-0003-3889-679X
Respiratory Department, School of Medicine, Patras University Hospital, Greece.
Theodoros Karampitsakos
Respiratory Department, School of Medicine, Patras University Hospital, Greece.
Lampros Lakkas
https://orcid.org/0000-0001-9401-3125
2nd Department of Cardiology, School of Medicine, University of Ioannina, Greece.
Lampros K. Michalis
2nd Department of Cardiology, School of Medicine, University of Ioannina, Greece.
Argyrios Tzouvelekis
Respiratory Department, School of Medicine, Patras University Hospital, Greece.

Platypnea-orthodeoxia Syndrome is characterized by clinically significant postural hypoxia. The full spectrum of the syndrome includes intracardial and extracardial abnormalities with R->L shunt. Various concurrent underlying physiological abnormalities are usually encountered that require thorough clinical and laboratory evaluation. A high clinical suspicion in patients with unexplained dyspnea is also required to reach a firm diagnosis. We herein present a rare case of an 82-years-old patient with episodic unexplained dyspnea, patent foramen ovale with normal pulmonary pressures and we review the underlying physiologic mechanisms.

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How to Cite

Sampsonas, Fotios, Matthaios Katsaras, Ourania Papaioannou, Theodoros Karampitsakos, Lampros Lakkas, Lampros K. Michalis, and Argyrios Tzouvelekis. 2021. “Platypnea Orthodeoxia Syndrome in a Patient With Patent Foramen Ovale and Normal Atrial Pressure. Case Report and Presentation of Underlying Pathophysiological Mechanisms”. Monaldi Archives for Chest Disease 92 (1). https://doi.org/10.4081/monaldi.2021.1878.
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