https://doi.org/10.4081/monaldi.2021.1878
Platypnea orthodeoxia syndrome in a patient with patent foramen ovale and normal atrial pressure. Case report and presentation of underlying pathophysiological mechanisms
Submitted: April 5, 2021
Accepted: June 13, 2021
Published: September 28, 2021
Accepted: June 13, 2021
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Platypnea-orthodeoxia Syndrome is characterized by clinically significant postural hypoxia. The full spectrum of the syndrome includes intracardial and extracardial abnormalities with R->L shunt. Various concurrent underlying physiological abnormalities are usually encountered that require thorough clinical and laboratory evaluation. A high clinical suspicion in patients with unexplained dyspnea is also required to reach a firm diagnosis. We herein present a rare case of an 82-years-old patient with episodic unexplained dyspnea, patent foramen ovale with normal pulmonary pressures and we review the underlying physiologic mechanisms.
Cheng TO. Platypnea-orthodeoxia syndrome: etiology, differential diagnosis, and management. Catheter Cardiovasc Interv1999;47:64-6.
DOI: https://doi.org/10.1002/(SICI)1522-726X(199905)47:1<64::AID-CCD15>3.0.CO;2-6
Agrawal A, Palkar A, Talwar A. The multiple dimensions of platypnea-orthodeoxia syndrome: A review. Respir Med 2017;129:31-8.
DOI: https://doi.org/10.1016/j.rmed.2017.05.016
Mojadidi MK, Ruiz JC, Chertoff J, et al. Patent foramen ovale and hypoxemia. Cardiol Rev 2019;27:34-40.
DOI: https://doi.org/10.1097/CRD.0000000000000205
Hagen PT, Scholz DG, Edwards WD. Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clin Proc 1984;59:17-20.
DOI: https://doi.org/10.1016/S0025-6196(12)60336-X
Kizer JR, Devereux RB. Clinical practice. Patent foramen ovale in young adults with unexplained stroke. N Engl J Med. 2005;353:2361-72.
DOI: https://doi.org/10.1056/NEJMcp043981
Lio KU, Jiménez D, Moores L, Rali P. Clinical conundrum: concomitant high-risk pulmonary embolism and acute ischemic stroke. Emerg Radiol 2020;27:433-9.
DOI: https://doi.org/10.1007/s10140-020-01772-7
Chen GP, Goldberg SL, Gill EA, Jr. Patent foramen ovale and the platypnea-orthodeoxia syndrome. Cardiol Clin 2005;23:85-9.
DOI: https://doi.org/10.1016/j.ccl.2004.10.003
Zanchetta M, Rigatelli G, Ho SY. A mystery featuring right-to-left shunting despite normal intracardiac pressure. Chest 2005;128:998-1002.
DOI: https://doi.org/10.1378/chest.128.2.998
Pierce CW. Platypnea-orthodeoxia syndrome in an elderly woman with a patent foramen ovale. Can J Cardiol 2010;26:213-4.
DOI: https://doi.org/10.1016/S0828-282X(10)70372-X
How to Cite
Sampsonas, Fotios, Matthaios Katsaras, Ourania Papaioannou, Theodoros Karampitsakos, Lampros Lakkas, Lampros K. Michalis, and Argyrios Tzouvelekis. 2021. “Platypnea Orthodeoxia Syndrome in a Patient With Patent Foramen Ovale and Normal Atrial Pressure. Case Report and Presentation of Underlying Pathophysiological Mechanisms”. Monaldi Archives for Chest Disease 92 (1). https://doi.org/10.4081/monaldi.2021.1878.
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