https://doi.org/10.4081/monaldi.2022.2045
Nonspecific interstitial pneumonia revealing an antisynthetase syndrome
Submitted: August 6, 2021
Accepted: October 12, 2022
Published: November 29, 2022
Accepted: October 12, 2022
Abstract Views: 885
PDF: 204
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
One of the most common interstitial lung diseases in antisynthetase syndrome is nonspecific interstitial pneumonia (NSIP). A 49-year-old woman presented with slow progression exertional dyspnea, myalgia, and arthralgia. The radiological findings indicated an NSIP pattern. Autoantibodies were found to be positive, but no lung biopsy was performed. Even though corticosteroid therapy significantly improved the patient's dyspnea, the patient developed mechanic's hands, the anti-synthetase antibody (PL12) became positive, and creatine phosphokinase (CPK) levels increased. As a result, the antisynthetase syndrome was established. The patient follow-up after three years revealed an improvement in symptoms under corticosteroid therapy.
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How to Cite
Moussa , Nedia, Rahma Gargouri, Mouna Snoussi, Rym Khemakhem, Zouhir Bahloul, and Samy Kammoun. 2022. “Nonspecific Interstitial Pneumonia Revealing an Antisynthetase Syndrome”. Monaldi Archives for Chest Disease 93 (3). https://doi.org/10.4081/monaldi.2022.2045.
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