https://doi.org/10.4081/monaldi.2021.2046
Pulmonary tuberculosis and COVID-19 coinfection: A new medical challenge
Submitted: August 7, 2021
Accepted: October 8, 2021
Published: December 3, 2021
Accepted: October 8, 2021
Abstract Views: 1620
PDF: 652
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Radiological findings in chest radiography and respiratory symptomatology represent a great challenge of interpretation during the COVID-19 (Coronavirus Disease 2019) pandemic, as their patterns can generate uncertainty at the time of diagnosis. This case highlights the importance in achieving an adequate correlation between diagnostic imaging and the clinical picture. We present a male adult who was admitted for 8 days of respiratory symptoms. Management with steroids was initiated according to the RECOVERY (Randomized Evaluation of COVID-19 Therapy) protocol and later confirmation of SARS-CoV-2 infection was received. In the following weeks, he deteriorated slowly and progressively clinically, without reaching respiratory failure. Imaging showed a thick-walled cavitation in the right lower lobe. Tuberculosis was suspected and confirmed. The uniqueness of this case of COVID-19 coinfection in a patient with undiagnosed tuberculosis, represents a diagnostic and clinical management challenge, where the proper interpretation of chest radiology is a fundamental tool.
Shereen MA, Khan S, Kazmi A, et al. COVID-19 infection: Emergence, transmission, and characteristics of human coronaviruses. J Adv Res 2020;24:91-98.
DOI: https://doi.org/10.1016/j.jare.2020.03.005
Umakanthan S, Sahu P, Ranade AV, et al. Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgrad M J 2020;96:753.
World Health Organization. Global tuberculosis report 2020. Last access 15 December 2020 Available from: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2020
Wei M, Zhao Y, QianZ, et al. Pneumonia caused by mycobacterium tuberculosis. Microbes infect 2020;22:278-84.
DOI: https://doi.org/10.1016/j.micinf.2020.05.020
Ufimtseva E, Eremeeva N, Vakhrusheva D, Skornyakov S. Mycobacterium tuberculosis shape and size variations in alveolar macrophages of tuberculosis patients. Eur Respir J 2019;54:PA4605.
DOI: https://doi.org/10.1183/13993003.congress-2019.PA4605
Churchyard G, Kim P, Shah NS, et al. What we know about tuberculosis transmission: An overview. J Infect Dis 2017;216:S629–35.
DOI: https://doi.org/10.1093/infdis/jix362
Migliori GB, Thong PM, Alffenaar J-W, et al. Gauging the impact of the COVID-19 pandemic on tuberculosis services: a global study. Eur Respir J 2021;58:2101786.
DOI: https://doi.org/10.1183/13993003.01786-2021
Vanzetti CP, Salvo CP, Kuschner P, Brusca S. [Coinfección tuberculosis y COVID-19].[Article in Spanish]. Medicina (B. Aires) 2020;80:s100-3.
Pai M, Behr MA, Dowdy D, et al. Tuberculosis. Nat Rev Dis Primers 2016;2:16076.
DOI: https://doi.org/10.1038/nrdp.2016.76
Osuchowski MF, Winkler MS, Skirecki T, et al. The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity. Lancet Respir Med 2021;9:622–42.
DOI: https://doi.org/10.1016/S2213-2600(21)00218-6
Mousquer GT, Peres A, Fiegenbaum M. Pathology of TB/COVID-19 Co-Infection: The phantom menace. Tuberculosis 2021;126:102020.
DOI: https://doi.org/10.1016/j.tube.2020.102020
Petrone L, Petruccioli E, Vanini V, et al. Coinfection of tuberculosis and COVID-19 limits the ability to in vitro respond to SARS-CoV-2. Int J Infect Dis 2021;S1201-9712(21)00176-4. Online ahead of print.
DOI: https://doi.org/10.1016/j.ijid.2021.02.090
Udwadia ZF, Vora A, Tripathi AR, et al. COVID-19-Tuberculosis interactions: When dark forces collide. Indian J Tuberc 2020;67:S155–62.
DOI: https://doi.org/10.1016/j.ijtb.2020.07.003
Nachiappan AC, Rahbar K, Shi X, et al. Pulmonary tuberculosis: Role of radiology in diagnosis and management. Radiographics 2017;37:52–72.
DOI: https://doi.org/10.1148/rg.2017160032
Kwee TC, Kwee RM. Chest CT in covid-19: What the radiologist needs to know. Radiographics 2020;40:1848–65.
DOI: https://doi.org/10.1148/rg.2020200159
Tadolini M, Codecasa LR, García-García JM, et al. Active tuberculosis, sequelae and COVID-19 co-infection: First cohort of 49 cases. Eur Respir J 2020;56:2001398.
DOI: https://doi.org/10.1183/13993003.01398-2020
RECOVERY Collaborative Group, Horby P, Lim WS, et al. Dexamethasone in Hospitalized Patients with Covid-19. N Engl J Med 2021;384:693-704.
DOI: https://doi.org/10.1056/NEJMoa2021436
Gopalaswamy R, Subbian S. Corticosteroids for covid-19 therapy: Potential implications on tuberculosis. Int J Mol Sci 2021;22:3773.
DOI: https://doi.org/10.3390/ijms22073773
Motta I, Centis R, D’Ambrosio L, et al. Tuberculosis, COVID-19 and migrants: Preliminary analysis of deaths occurring in 69 patients from two cohorts. Pulmonology 2020;26:233-40.
DOI: https://doi.org/10.1016/j.pulmoe.2020.05.002
How to Cite
Osejo-Betancourt, Miguel, Sebastian Molina-Paez, and Mariana Rubio-Romero. 2021. “Pulmonary Tuberculosis and COVID-19 Coinfection: A New Medical Challenge”. Monaldi Archives for Chest Disease 92 (3). https://doi.org/10.4081/monaldi.2021.2046.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Daniele Magnini, Emilio Bria, Alessandra Cancellieri, Vanina Livi, Fausto Leoncini, Marco Ferrari, Teresa Bruni, Daniela Paioli, Rocco Trisolini, Bronchoscopically-visible massive central airway cancer cavitation is associated with metastatic disease, lack of actionable mutations and poor prognosis: a case series , Monaldi Archives for Chest Disease: Early Access
- Benhur Joel Shadrach, Rishabh Goel, Kunal Deokar, Anukool Jain, Invasive pulmonary aspergillosis in a COVID-19 recovered patient: unravelling an infective sequalae of the SARS-CoV-2 virus , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Anu Anna George, Kevin John John, Anil Jha, Ajay Kumar Mishra, Infections precipitating Takotsubo cardiomyopathy, an uncommon complication of a common infection , Monaldi Archives for Chest Disease: Vol. 93 No. 3 (2023)
- Yamini Marimuthu, Radhika Kunnavil, NS Anil, Sharath Burugina Nagaraja, N Satyanarayana, Jeetendra Kumar, Bojja Ramya, Clinical profile and risk factors for mortality among COVID-19 inpatients at a tertiary care centre in Bengaluru, India , Monaldi Archives for Chest Disease: Vol. 91 No. 3 (2021)
- Oleksandr Korotych, Andrei Dadu, Askar Yedilbayev, Masoud Dara, Operational research as an instrument to address the critical gaps for effective treatment of tuberculosis in eastern Europe and central Asia , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Carmine Guarino, Cristiano Cesaro, Giuseppe Fiorentino, Francesco Rossi, Benedetto Maria Polverino, Fiorentino Fragranza, Luca Monastra, Patrizia Murino, Enzo Zamparelli, Giuseppe La Cerra, Bronchoscopy in COVID-19 patients: When, how and why. Experience in clinical practice , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Karrar Al-Buthabhak , Hussein Nafakhi, Mohammed H. Shukur , Ahmed Nafakhi, Mohammed Alareedh, Foaad Shaghee, Blood indices, in-hospital outcome and short-term prognosis in patients with COVID-19 pneumonia , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Shekhar Kunal, Vijay Pathak, Keshav Pathak, Monika Mishra, Shashi Mohan Sharma, Sudhir Bhandari, Very late stent thrombosis associated with COVID-19 infection: a case report and review of the literature , Monaldi Archives for Chest Disease: Vol. 92 No. 2 (2022)
- Laura Bertacchini, Mara Paneroni, Laura Comini, Simonetta Scalvini, Michele Vitacca, Recovering of oxygenation, physical function and disability in patients with Covid-19 , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Amit Gupta, Aman Snehil, Sujeet Kumar, Roshan Chanchlani, Reyaz Ahmad, Keerti Swarnkar, Garima Goel, Bronchiectasis without lower respiratory symptoms in the presence of multisystem anomalies – a clinical clue to diagnose esophageal lung anomaly , Monaldi Archives for Chest Disease: Vol. 93 No. 1 (2023)
<< < 17 18 19 20 21 22 23 24 25 > >>
You may also start an advanced similarity search for this article.
