https://doi.org/10.4081/monaldi.2021.2047
Six minute walk test in Italian children with cystic fibrosis aged 6 and 11
Published: December 28, 2021
Abstract Views: 1620
PDF: 712
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Six minute walk test (6MWT) is a field exercise test widely used in clinical practice, both in adults and in pediatric patients. The primary aim of the study is to evaluate the physical performance of the subjects and compare them with the predicted Italian values. The secondary aim is to verify the possible relationship between the 6MWT distance (6MWD) and the clinical variables of the sample. Italian children between 6-11 years affected by CF were recruited from 9 regional centers for CF. Short questionnaire assessments about their health state and physical activity routine was administered. Anthropometric characteristics were measured before the test and, peripheral oxygen saturation (SpO2), heart and respiratory rate were measured before and after a 6-minute walk test. The tests were performed according to the American Thoracic Society (ATS) guidelines. 6MWD was compared with the predicted distance calculated by the reference equation for healthy subjects of the same age. A total of 132 children were recruited (70 male) and completed the assessment. The mean (±SD) for 6MWD was 557.4 (±69.9), male = 551.4 (±80.0), female = 560.4 (±63.3), however the predicted distance mean was 605 m. A total of 101(76.5%) subjects practice regular physical activity. A total of 31 (23%) had a FEV1 lower than their lower limits of normal (LLN). Functional performance on the 6MWT was poorer among the CF patients than among the predicted distance estimated with Italian values. The correlation with the amount of physical activity and 6MWD has been verified.
Ziegler B, Rovedder PM, Lukrafka JL, et al. Submaximal exercise capacity in adolescent and adult patients with cystic fibrosis. J Bras Pneumol 2007;33:263-9.
Sahlberg ME, Svantesson U, Thomas EM, Strandvik B. Muscular strength and function in patients with cystic fibrosis. Chest 2005;127:1587-92.
Peterson ML, Jacobs DR Jr, Milla CE. Longitudinal changes in growth parameters are correlated with changes in pulmonary function in children with cystic fibrosis. Pediatrics 2003;112:588-92.
Arikan H, Yatar L, Calik-Kutukcu E, et al. A comparison of respiratory and peripheral muscle strength, functional exercise capacity, activities of daily living and physical fitness in patients with cystic fibrosis and healthy subjects. Res Develop Disabil 2015;45-46:147-56.
Orenstein DM, Higgins LW. Update on the role of exercise in cystic fibrosis. Curr Opin Pulm Med 2005;11:519–23.
Schneiderman-Walker J, Pollock SL, Corey M, et al. A randomized controlled trial of a 3-year home exercise program in cystic fibrosis. J Pediatr 2000;136:304-10.
Coelho CC, Aquino Eda S, de Almeida DC, et al. Comparative analysis and reproducibility of the modified shuttle walk test in normal children and in children with cystic fibrosis. J Bras Pneumol 2007;33:168-74.
Lima C, de Andrade A, Campos S, et al. Six-minute walk test as a determinant of the functional capacity of children and adolescents with cystic fibrosis: A systematic review. Respir Med 2018;137:83–8.
Pereira FM, Ribeiro MÂ, Ribeiro AF, et al. Functional performance on the six-minute walk test in patients with cystic fibrosis. J Bras Pneumol 2011;37:735-44.
Hassan J, van der Net J, Helders PJ, et al. Six-minute walk test in children with chronic conditions. Br J Sports Med 2010;44:270-4.
Gulmans VA, van Veldhoven NH, de Meer K, Helders PJ. The six-minute walking test in children with cystic fibrosis: reliability and validity. Pediatr Pulmonol 1996;22:85-9.
Cunha MT, Rozov T, Caitano de Olivera R, Jardim JR. Six minutes walk test in children and adolescents with cystic fibrosis. Pediatr Pulmonol 2006;41:618-22.
Vandoni M, Correale L, Puci MV, et al. Six minute walk distance and reference values in healthy Italian children: A cross-sectional study. PLoS One 2018;13:e0205792.
Geiger R, Strasak A, Treml B, et al. Six-minute walk test in children and adolescents. J Pediatr 2007;150:395–9.
Lammers AE, Hislop AA, Flynn Y, Haworth SG. The 6-minute walk test: normal values for children of 4–11 years of age. Arch Dis Child 2008;93:464-8.
Ulrich S, Hildenbrand FF, Treder U, et al. Reference values for the 6-minute walk test in healthy children and adolescents in Switzerland. BMC Pulm Med 2013;13:49.
Farrell PM, White TB, Ren CL, et al. Diagnosis of cystic fibrosis: Consensus guidelines from the Cystic Fibrosis Foundation. J Pediatr 2017;184:243.
ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS Statement. Guidelines for the Six-Minute Walk Test. Am J Respir Crit Care Med 2002;166:111–7. Erratum in ATS Statement: Guidelines for the Six-Minute Walk Test. Am J Respir Crit Care Med 2016;193:1185.
European Cystic Fibrosis Society. ECFS Patient Registry. Annual Data Report 2017 data. Accessed ON: 22 December 2020. Available from: https://www.ecfs.eu/sites/default/files/general-content-images/working-groups/ecfs-patient-registry/ECFSPR_Report2017_v1.3.pdf
Quanjer PH, Stanojevic S, Cole TJ, et al. Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations the ERS Global Lung Function Initiative. Eur Respir J 2012;40;1324-43.
Flume PA, O'Sullivan BP, Robinson KA, et al Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med 2007;176:957-69.
Gruber W, Orenstein DM, Braumann KM, Huls G. Health-related fitness and trainability in children with cystic fibrosis. Pediatr Pulmonol 2008;43:953-64.
Lesser DJ, Fleming MM, Maher CA, et al. Does the 6-min walk test correlate with the exercise stress test in children? Pediatr Pulmonol 2010;45:135-40.
Troosters T, Langer D, Vrijsen B, et al. Skeletal muscle weakness, exercise tolerance and physical activity in adults with cystic fibrosis. Eur Respir J 2009;33:99-106.
Priesnitz CV, Rodrigues GH, Stumpf da Silva C, et al. Reference values for the 6-min walk test in healthy children aged 6-12 years. Pediatr Pulmonol 2009;44:1174-9.
Troosters T, Gosselink R, Decramer M. Six minute walking distance in healthy elderly subjects. Eur Respir J 1999;14:270-4.
Chetta A, Pisi G, Zanini A, et al. Six-minute walking test in cystic fibrosis adults with mild to moderate lung disease: comparison to healthy subjects. Respir Med 2001;95:986-91.
Gomez Punter RM, Girón Moreno RM, Vázquez Espinosa E, et al. Desaturations during 6-minute walk test and predicting nocturnal desaturations in adult subjects with cystic fibrosis. Respir Care 2019;64:48-54.
Rayment JH, Stanojevic S, Davis SD, et al. Lung clearance index to monitor treatment response in pulmonary exacerbations in preschool children with cystic fibrosis. Thorax 2018;73:451-8.
Saad HB, Prefaut C, Missaoui R, et al. Reference equation for 6-min walk distance in healthy North African children 6-16 years old. Pediatr Pulmonol 2009;44:316-24.
How to Cite
Innocenti, Diletta, Eleonora Masi, Giovanni Taccetti, Marco Genito, Elena Balestri, Anna Rita Berghelli, Maria Antonietta Ciciretti, et al. 2021. “Six Minute Walk Test in Italian Children With Cystic Fibrosis Aged 6 and 11”. Monaldi Archives for Chest Disease 92 (3). https://doi.org/10.4081/monaldi.2021.2047.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- R.W. Dal Negro, A. Testa, R. Aquilani, S. Tognella, E. Pasini, A. Barbieri, F. Boschi, Essential amino acid supplementation in patients with severe COPD: a step towards home rehabilitation , Monaldi Archives for Chest Disease: Vol. 77 No. 2 (2012): Pulmonary series
- Giuseppe Caminiti, Maurizio Volterrani, Ferdinando Iellamo, Giuseppe Marazzi, Marco Silvestrini, Domenico Mario Giamundo, Valentina Morsella, Deborah Di Biasio, Alessio Franchini, Marco Alfonso Perrone, Exercise training for patients with heart failure and preserved ejection fraction. A narrative review , Monaldi Archives for Chest Disease: Early Access
- Marie Christine Iliou, Jean Christophe Blanchard, Aurélia Lamar-Tanguy, Pascal Cristofini, François Ledru, Cardiac rehabilitation in patients with pacemakers and implantable cardioverter defibrillators , Monaldi Archives for Chest Disease: Vol. 86 No. 1-2 (2016): Cardiac series
- E.A. Renzoni, Interstitial lung disease in systemic sclerosis , Monaldi Archives for Chest Disease: Vol. 67 No. 4 (2007): Pulmonary series
- D. Scala, S. Cozzolino, G. D’Amato, G. Cocco, A. Sena, P. Martucci, E. Ferraro, A.A. Mancini, Sharing knowledge is the key to success in a patient-physician relationship: how to produce a patient information leaflet on COPD , Monaldi Archives for Chest Disease: Vol. 69 No. 2 (2008): Pulmonary series
- E. Clini, S. Costi, M. Romagnoli, F. Florini, Rehabilitation of COPD patients: which training modality , Monaldi Archives for Chest Disease: Vol. 61 No. 3 (2004): Pulmonary series
- Alessandro Mezzani, Francesco Cacciatore, Raffaella Catanzaro, Alessandra Gualco, Daniela Guzzetti, Dario Leosco, Mauro Monelli, Franco Tarro Genta, Paolo Totaro, Egidio Traversi, Emanuela Zanelli, Pantaleo Giannuzzi, A multicenter, randomized, controlled trial on short-term feasibility and impact on functional capacity, symptoms and neurohumoral activation , Monaldi Archives for Chest Disease: Vol. 82 No. 1 (2014): Cardiac series
- Madalina Macrea, Richard ZuWallack, Linda Nici, There’s no place like home: Integrating pulmonary rehabilitation into the home setting , Monaldi Archives for Chest Disease: Vol. 87 No. 2 (2017)
- Laura Bertacchini, Mara Paneroni, Laura Comini, Simonetta Scalvini, Michele Vitacca, Recovering of oxygenation, physical function and disability in patients with Covid-19 , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Paolo Ruggeri, Federica Lo Bello, Francesco Nucera, Michele Gaeta, Francesco Monaco, Gaetano Caramori, Giuseppe Girbino, Hereditary hyperhomocysteinemia associated with nephrotic syndrome complicated by artery thrombosis and chronic thromboembolic pulmonary hypertension: A case report , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
<< < 4 5 6 7 8 9 10 11 12 13 > >>
You may also start an advanced similarity search for this article.
