https://doi.org/10.4081/monaldi.2022.2054
Usefulness of CURB-65, pneumonia severity index and MuLBSTA in predicting COVID-19 mortality
Accepted: February 14, 2022
Supplementary: 203
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The aim of our study is to evaluate the accuracy of CURB-65 and Pneumonia Severity Index (PSI), the most widely used scores for community acquired pneumonia, and MuLBSTA, a viral pneumonia score, in predicting 28-day mortality in Coronavirus Disease 2019 (COVID-19) pneumonia.We retrospectively collected clinical data of consecutive patients with laboratory-confirmed COVID-19 pneumonia admitted at Papa Giovanni XXIII Hospital from February 23rd to March 14th, 2020. We calculated at Emergency Department (ED) presentation CURB-65, PSI and MuLBSTA and we compared their performances in discriminating between survivors and non-survivors at 28 days. Among 431 hospitalized patients, the majority presented with hypoxic respiratory failure: median (interquartile range, IQR) PaO2/FiO2 ratio at admission was 228.6 (142.0-278.1). In the first 24 hours, 111 (27%) patients were administered low-flow oxygen cannula, 50 (12%) Venturi Mask, 95 (23%) non-rebreather mask, 106 (26%) non-invasive ventilation, 12 (3%) mechanical ventilation and 41 (9%) were not administered oxygen therapy. Mortality rate at 28-day was 35% (150/431). Between survivors and non-survivors, median (IQR) scores were, respectively, 1.0 (1.0-2.0) and 2.0 (2.0-3.0) for CURB-65 (p<0.001); 90.5 (76.0-105.5) and 115.0 (100.0-129.0) for PSI (p<0.001); 7.0 (5.0-10.0) and 11.0 (9.0-13.0) for MuLBSTA (p<0.001). Areas under the receiver operating characteristic curve (AUCs) for each score were, respectively, 0.725 (0.662-0.787), 0.776 (0.693-0.859) and 0.743 (0.680-0.806) (p>0,05). PSI and MuLBSTA did not show a better performance when compared to CURB-65. Although CURB-65, PSI and MuLBSTA scores are useful tools to discriminate between survivors and non-survivors in COVID-19 pneumonia, their diagnostic accuracy in discriminating 28-day mortality in COVID-19 pneumonia is moderate, as confirmed by AUCs <0.80, and there is a potential underestimation of disease severity in the low-risk classes. For this reason, they should not be recommended in ED to decide between inpatient and outpatient management in patients affected by COVID-19 pneumonia.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- G. Passalacqua, E. Compalati, M. Schiappoli, G. Senna, Complementary and alternative medicine for the treatment and diagnosis of asthma and allergic diseases , Monaldi Archives for Chest Disease: Vol. 63 No. 1 (2005): Pulmonary series
- Francesco Giallauria, Neil Andrew Smart, Antonio Cittadini, Carlo Vigorito, Exercise training modalities in chronic heart failure: does high intensity aerobic interval training make the difference? , Monaldi Archives for Chest Disease: Vol. 86 No. 1-2 (2016): Cardiac series
- Massimo F. Piepoli, Antonio Brambilla, Lorenzo Brambilla, Claudio Ceconi, Paolo Coruzzi, Ursula Corvi, Tommaso Diaco, Giuseppe Di Pasquale, Alessandro Malagoli, Giuseppe Miserotti, Andrea Pozzati, Pier Luigi Semprini, Enrico Sverzellati, Stefano Urbinati, Giovanni Q. Villani, Preventive Cardiology: comparisons of European and Italian projects with the Cardiac Units from Emilia Romagna region. A workshop of IACPR/GICR - Emilia Romagna , Monaldi Archives for Chest Disease: Vol. 76 No. 2 (2011): Cardiac series
- Ugo Corrà , Massimo Pistono, Alessandro Mezzani, Marco Gnemmi, Franco Tarro Genta, Roberto Caruso, Pantaleo Giannuzzi, Cardiovascular prevention and rehabilitation for patients with ventricular assist device From exercise therapy to long-term therapy Part I: exercise therapy , Monaldi Archives for Chest Disease: Vol. 76 No. 1 (2011): Cardiac series
- Franco Tarro Genta, Elena Colajanni, Pierluigi Sbarra, Massimo Tidu, Mauro Rinaldi, Enzo Bosimini, Flow mediated dilation in patient with Berlin Heart Incor left ventricle assist device , Monaldi Archives for Chest Disease: Vol. 70 No. 1 (2008): Cardiac series
- F. Cortopassi, A.A.M. Castro, E.F. Porto, M. Colucci, G. Fonseca, L. Torre-Bouscoulet, V. Iamonti, J.R. Jardim, Comprehensive exercise training improves ventilatory muscle function and reduces dyspnea perception in patients with COPD , Monaldi Archives for Chest Disease: Vol. 71 No. 3 (2009): Pulmonary series
- U. Caterino, G. Dialetto, F.E. Covino, G. Mazzarella, E. Grella, M. Massimo, The usefulness of transesophageal echocardiography in the staging of locally advanced lung cancer , Monaldi Archives for Chest Disease: Vol. 67 No. 1 (2007): Pulmonary series
- Takeshi Terashima, Takahiro Nakajima, Tatsu Matsuzaki, Eri Iwami, Takeo Shibui, Takeshi Nomura, Akira Katakura, Chewing ability and desaturation during chewing in patients with COPD , Monaldi Archives for Chest Disease: Vol. 89 No. 3 (2019)
- Fabrizio Corsini, Anna Scaglione, Maria Iacomino, Giuseppe Mascia, Saverio Melorio, Carmine Riccio, Salvatore Romano, Alfredo Vetrano, Silvana Celardo, Giancarlo Corsini, Carmelo Chieffo, Acute myocardial infarction in the elderly. A case-control study with a younger population and review of literature , Monaldi Archives for Chest Disease: Vol. 66 No. 1 (2006): Cardiac series
- L. Bianchi, M. Vitacca, Non-invasive mechanical ventilation: a practice not for all seasons , Monaldi Archives for Chest Disease: Vol. 65 No. 3 (2006): Pulmonary series
<< < 29 30 31 32 33 34 35 36 37 38 > >>
You may also start an advanced similarity search for this article.
