https://doi.org/10.4081/monaldi.2021.2098
Left atrial invasion of a lung cancer: a case report
Submitted: September 25, 2021
Accepted: November 2, 2021
Published: December 3, 2021
Accepted: November 2, 2021
Abstract Views: 1201
PDF: 425
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Lung cancer is the leading neoplastic form worldwide for both incidence and mortality and represents the largest contributor to new cancer diagnosis. Cardiac extensions of a pulmonary neoplasm are rare and dramatically under-diagnosed because of the extreme variability of clinical presentation and frequently are expression of an advanced-stage primary lung cancer. The invasion often happens through pulmonary veins in absence of a clear respiratory impairment. Symptoms related to the cardiac involvement as the first presentation of a malignant pulmonary neoplasm are very uncommon and related with poor outcome. Here we present a case of invasion of the left atrium of a pulmonary neoplasm with initial cardiac manifestations and a laboratory finding of hypercalcemia.
Lin MT, Ku SC, Wu MZ, Yu CJ. Intracardiac extension of lung cancer via the pulmonary vein. Thorax 2008;63:1122.
DOI: https://doi.org/10.1136/thx.2007.090373
Weinberg BA, Conces DJ Jr, Waller BF. Cardiac manifestations of noncardiac tumors. Part I: Direct effects. Clin Cardiol 1989;12:289-96.
DOI: https://doi.org/10.1002/clc.4960120512
Stewart AF. Clinical practice. Hypercalcemia associated with cancer. N Engl J Med 2005;352:373-9
DOI: https://doi.org/10.1056/NEJMcp042806
Otero J, Lenihan DJ. The "normothermic" Osborn wave induced by severe hypercalcemia. Tex Heart Inst J 2000;27:316-7.
Cipriano F, Dessoti LU, Rodrigues AJ, et al. Report of a lung carcinoma extended to the left atrium through pulmonary vein. J Thorac Dis 2018;10:E46-E51.
DOI: https://doi.org/10.21037/jtd.2017.12.33
Watanabe N, Kubo K. Images in cardiology: Intra-left atrial invasive mass extended via the pulmonary vein. Heart 2001;85:271.
DOI: https://doi.org/10.1136/heart.85.3.271
Ballo P, Laureano R, Briganti M, et al. Left atrial mass invasion from pulmonary neoplasm extension via the right upper pulmonary vein presenting as ipsilateral stroke. Case Rep Med 2016;2016:7084234.
DOI: https://doi.org/10.1155/2016/7084234
Brandt RR, Rubin J, Reeder GS. Intracardiac extension of a lung tumor causing left ventricular inflow obstruction. J Am Soc Echocardiogr 1995;8:930-3.
DOI: https://doi.org/10.1016/S0894-7317(05)80019-7
Chandra R, Abugroun A, Goldberg A, et al. Small cell lung cancer invading the left atrium with subsequent malignant embolic stroke: A case report and review of literature. Cardiol Res 2019;10:188-92.
DOI: https://doi.org/10.14740/cr752w
Hamilton F, Carroll R, Hamilton W, Salisbury C. The risk of cancer in primary care patients with hypercalcaemia: a cohort study using electronic records. Br J Cancer 2014;111:1410-2.
DOI: https://doi.org/10.1038/bjc.2014.433
Edwards CM, Johnson RW. From good to bad: The opposing effects of PTHrP on tumor growth, dormancy, and metastasis throughout cancer progression. Front Oncol 2021;11:644303.
DOI: https://doi.org/10.3389/fonc.2021.644303
Mirrakhimov AE. Hypercalcemia of malignancy: An update on pathogenesis and management. N Am J Med Sci 2015;7:483-93.
DOI: https://doi.org/10.4103/1947-2714.170600
Htwe KK, Aung TT. Diagnostic challenges of a mass in the left atrium. Cureus 2020;12:e8620.
DOI: https://doi.org/10.7759/cureus.8620
How to Cite
Cacciapuoti, Fulvio, Erica Vetrano, and Federico Cacciapuoti. 2021. “Left Atrial Invasion of a Lung Cancer: A Case Report”. Monaldi Archives for Chest Disease 92 (3). https://doi.org/10.4081/monaldi.2021.2098.
Copyright (c) 2021 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Soibam Pahel Meitei, Sudheer Tale, Arjun Kumar Negi, Ruchi Dua, Rohit Walia, Sudhir Saxena, Prevalence and characteristics of venous thromboembolism in severe exacerbation of chronic obstructive pulmonary disease in a tertiary care hospital in India , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Vipul Prakash, Arjun Kumar, Lokesh Kumar Saini, Barun Kumar, Girish Sindhwani, Prakhar Sharma, Ruchi Dua, Ravi Gupta, Mayank Mishra, Proportion of sleep-related breathing disorders and their association with echocardiographic parameters in stable patients with chronic obstructive pulmonary disease: a cross-sectional observational exploratory study , Monaldi Archives for Chest Disease: Early Access
- Federico Raimondi, Caterina Conti, Luca Novelli, Francesco Tarantini, Giuseppe Ciaravino, Piermario Scuri, Aurelia Grosu, Daniela Chinaglia, Lorenzo S.C. Grazioli, Andrea Gianatti, Ferdinando L. Lorini, Michele Senni, Fabiano Di Marco, A 57-year-old man with rapidly progressive pulmonary hypertension , Monaldi Archives for Chest Disease: Vol. 92 No. 1 (2022)
- Rajesh Venkataram, Srividya Arjuna, Giridhar Belur Hosmane, Anirban Chakraborty, Quantitative analysis of cell-free DNA by droplet digital PCR reveals the presence of EGFR mutations in non-malignant lung pathologies , Monaldi Archives for Chest Disease: Vol. 91 No. 3 (2021)
- C.A. Lindemans, R.A. Bruinsma, P.G.J. Nikkels, F.H.L. Bröker, H.G.M. Arets, Pulmonary consolidation and inflammation: inflammatory pseudotumour in young children , Monaldi Archives for Chest Disease: Vol. 71 No. 2 (2009): Pulmonary series
- Marco Ambrosetti, Mario Salerno, Walter Ageno, Roberto Tramarin, Roberto FE Pedretti, Is physical training contraindicated in patients with deep vein thrombosis during cardiac rehabilitation? , Monaldi Archives for Chest Disease: Vol. 64 No. 1 (2005): Cardiac series
- Alfonso Sforza, Maria Viviana Carlino, Mario Guarino, Salvatore Russo, Giovanni Albano, Fiorella Paladino, Costantino Mancusi, A case of pulmonary edema: The critical role of lung-heart integrated ultrasound examination , Monaldi Archives for Chest Disease: Vol. 88 No. 3 (2018)
- P.A. Canessa, L. Pratticò, L. Bancalari, F. Fedeli, B. Bacigalupo, S. Silvano, Respiratory bronchiolitis associated with interstitial lung disease , Monaldi Archives for Chest Disease: Vol. 61 No. 3 (2004): Pulmonary series
- Ugo Corrà , Massimo F. Piepoli, Summary Statement on Cardiopulmonary Exercise Testing in Chronic Heart Failure due to Left Ventricular Dysfunction Recommendations for Performance and Interpretation , Monaldi Archives for Chest Disease: Vol. 68 No. 1 (2007): Cardiac series
- A.M. Moretti, S. Tafuri, D. Parisi, C. Germinario, Epidemiology of Pulmonary Embolism in Apulia from analysis of current data , Monaldi Archives for Chest Disease: Vol. 73 No. 1 (2010): Pulmonary series
<< < 8 9 10 11 12 13 14 15 16 17 > >>
You may also start an advanced similarity search for this article.
