https://doi.org/10.4081/monaldi.2022.2135

Effect of COVID-19 vaccination status on outcome of adult patients admitted at a tertiary care centre in India

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Vol. 93 No. 1 (2023)
Submitted: October 24, 2021
Accepted: April 13, 2022
Published: April 19, 2022
COVID-19, Mortality, Vaccine
Abstract Views: 897
PDF: 174
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Authors

Bineet Ahluwalia
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Neeraj Kumar Gupta
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Amitabh Singh
Department of Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Pranav Ish
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Nishanth Dev
Department of Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Santvana Kohli
Department of Anesthesiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Rohit Kumar
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Fellisha Marwein
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.
Nitesh Gupta
niteshgupta2107@gmail.com
Department of Pulmonary and Critical Care Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi , India.

COVID-19 vaccination was initially started in India on 16th January 2021 after approval from national authorities. This study was carried out to assess the effect of vaccination status on the severity and clinical outcome among patients infected with COVID-19. The study included all adult COVID-19 patients admitted to our hospital from 1st April to 30th June 2021. A total of 819 patients were enrolled in the study out of which only 183 (22.3%) were vaccinated. The study documented a statistically significant reduction in the severity of illness among the vaccinated (single/double dose) (33% severe COVID-19) against the unvaccinated (43% severe COVID-19) groups; along with a reduction in mortality. On univariate and multivariate analysis, age, severity of illness and lack of COVID-19 vaccination status were associated with a statistically significant increased mortality. To conclude, this study demonstrates the role of vaccination in decreasing the severity and mortality of COVID-19 infection.

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Citations

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How to Cite

Ahluwalia, Bineet, Neeraj Kumar Gupta, Amitabh Singh, Pranav Ish, Nishanth Dev, Santvana Kohli, Rohit Kumar, Fellisha Marwein, and Nitesh Gupta. 2022. “Effect of COVID-19 Vaccination Status on Outcome of Adult Patients Admitted at a Tertiary Care Centre in India”. Monaldi Archives for Chest Disease 93 (1). https://doi.org/10.4081/monaldi.2022.2135.
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