https://doi.org/10.4081/monaldi.2022.2360

Thoracic follicular dendritic cell sarcoma - an outlandish presentation of a rare tumour with review of literature

Vol. 93 No. 2 (2023)
Submitted: June 25, 2022
Accepted: September 8, 2022
Published: September 20, 2022
follicular dendritic cell sarcoma, primary pulmonary, endobronchial spread, pneumonectomy, diagnostic dilemma
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Authors

Vinay V
docvinayv@gmail.com
https://orcid.org/0000-0003-1691-2111
Department of Tuberculosis and Respiratory Diseases, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Saraansh Bansal
https://orcid.org/0000-0003-1373-7207
Department of Thoracic Surgery, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Pallavi Purwar
https://orcid.org/0000-0002-3893-7662
Department of Thoracic Surgery, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Ravindra Kumar Dewan
https://orcid.org/0000-0002-1936-7764
Department of Thoracic Surgery, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Paras Verma
https://orcid.org/0000-0001-5426-2354
Department of Tuberculosis and Respiratory Diseases, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Shalini Mullick
https://orcid.org/0000-0002-5842-4100
Department of Pathology, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Mallika Dixit
https://orcid.org/0000-0002-5722-3120
Department of Pathology, Core Diagnostics-Gurgaon, Haryana, India.
B Rama Phanindra
https://orcid.org/0000-0002-5155-7541
Department of Thoracic Surgery, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.
Kanishk Siddhartha
https://orcid.org/0000-0002-0165-0836
Department of Thoracic Surgery, National Institute of Tuberculosis and Respiratory Diseases (NITRD), New Delhi, India.

Follicular dendritic cell sarcoma is a rare low grade malignant neoplasm that arises from follicular dendritic cells in lymphoid tissue germinal centres and accounts for 0.4% of all soft tissue sarcomas. It is extremely rare to have pulmonary follicular dendritic cell sarcoma with endobronchial extension and as an anterior mediastinal mass with mediastinal lymph node involvement. We present the case of a 34-year-old male non-smoker who had been experiencing chest pain for three months. A lobulated left peri-hilar mass with endobronchial spread into the left main bronchus and mediastinal lymphadenopathy was identified on a chest CT. The bronchoscope-guided cryobiopsy of the endobronchial mass was inconclusive. After a thorough multidisciplinary discussion, the patient underwent left sided pneumonectomy, mediastinal mass resection, and systematic lymph node dissection. Histologic examination using immunohistochemistry revealed follicular dendritic cell sarcoma.

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How to Cite

V, Vinay, Saraansh Bansal, Pallavi Purwar, Ravindra Kumar Dewan, Paras Verma, Shalini Mullick, Mallika Dixit, B Rama Phanindra, and Kanishk Siddhartha. 2022. “Thoracic Follicular Dendritic Cell Sarcoma - an Outlandish Presentation of a Rare Tumour With Review of Literature”. Monaldi Archives for Chest Disease 93 (2). https://doi.org/10.4081/monaldi.2022.2360.
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