https://doi.org/10.4081/monaldi.2022.2388
Alectinib rescue therapy in advanced ALK rearranged lung adenocarcinoma: a case report
Submitted: July 27, 2022
Accepted: September 14, 2022
Published: September 20, 2022
Accepted: September 14, 2022
Abstract Views: 1112
PDF: 218
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Alectinib is a highly selective tyrosine kinase inhibitor of anaplastic lymphoma kinase (ALK) that is approved as first-line treatment in adult patients with ALK-positive non-small cell lung cancer (NSCLC) and as second-line in patients previously treated with crizotinib, and has been shown in the literature to significantly prolong progression-free survival compared to chemotherapy in patients with advanced non-small cell lung cancer. The authors describe a clinical case of a 24-year-old woman with malignant massive pleural effusion caused by ALK rearranged pulmonary adenocarcinoma with pleural and pericardial metastasis, in which, despite a dramatic clinical debut, the correct and timely management of the diagnostic and therapeutic path allowed for extraordinary therapeutic success.
Porcel JM, Gasol A, Bielsa S, et al. Clinical features and survival of lung cancer patients with pleural effusions. Respirology 2015;20:654-9.
DOI: https://doi.org/10.1111/resp.12496
Comella P, Frasci G, De Cataldis G, et al. Cisplatin/carboplatin + etoposide + vinorelbine in advanced non-small-cell lung cancer: a multicentre randomised trial. Gruppo Oncologico Campano. Br J Cancer 1996;74:1805-11.
DOI: https://doi.org/10.1038/bjc.1996.634
Cattaneo F, Guerra G, Parisi M, et al. Expression of formyl-peptide receptors in human lung carcinoma. Anticancer Res 2015;35:2769-74.
Bianco A, Perrotta F, Barra G, et al. Prognostic factors and biomarkers of responses to immune checkpoint inhibitors in lung cancer. Int J Mol Sci 2019;20:4931.
DOI: https://doi.org/10.3390/ijms20194931
Perrotta F, Rocco D, Vitiello F, et al. Immune checkpoint blockade for advanced NSCLC: A new landscape for elderly patients. Int J Mol Sci 2019;20:2258.
DOI: https://doi.org/10.3390/ijms20092258
Cameron LB, Hitchen N, Chandran E, et al. Targeted therapy for advanced anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer. Cochrane Database Syst Rev 2022;1:CD013453.
DOI: https://doi.org/10.1002/14651858.CD013453.pub2
Golding B, Luu A, Jones R, Viloria-Petit AM. The function and therapeutic targeting of anaplastic lymphoma kinase (ALK) in non-small cell lung cancer (NSCLC). Mol Cancer 2018;17:52.
DOI: https://doi.org/10.1186/s12943-018-0810-4
Moore DA, Benafif S, Poskitt B, et al. Optimising fusion detection through sequential DNA and RNA molecular profiling of non-small cell lung cancer. Lung Cancer 2021;161:55-9.
DOI: https://doi.org/10.1016/j.lungcan.2021.08.008
Doxtader EE, Cheng YW, Zhang Y. Molecular testing of non-small cell lung carcinoma diagnosed by endobronchial ultrasound-guided transbronchial fine-needle aspiration: The Cleveland clinic experience. Arch Pathol Lab Med 2019;143:670-6.
DOI: https://doi.org/10.5858/arpa.2017-0184-RA
Perrotta F, Nankivell M, Adizie JB, et al. Endobronchial ultrasound-guided transbronchial needle aspiration for PD-L1 testing in non-small cell lung cancer. Chest 2020;158:1230-9.
DOI: https://doi.org/10.1016/j.chest.2020.04.059
Ando K, Akimoto K, Sato H, et al. Brigatinib and alectinib for ALK rearrangement-positive advanced non-small cell lung cancer with or without central nervous system metastasis: A systematic review and network meta-analysis. Cancers (Basel) 2020;12:942.
DOI: https://doi.org/10.3390/cancers12040942
Serritella AV, Bestvina CM. Anaplastic lymphoma kinase mutation-positive non-small cell lung cancer. Thorac Surg Clin 2020;30:137-46.
DOI: https://doi.org/10.1016/j.thorsurg.2019.12.001
How to Cite
Cesaro, Cristiano, Umberto Caterino, Fabio Perrotta, Umberto Masi, Alessandra Cotroneo, Roberta Cianci, Enzo Zamparelli, Flavio Cesaro, Dario Amore, and Danilo Rocco. 2022. “Alectinib Rescue Therapy in Advanced ALK Rearranged Lung Adenocarcinoma: A Case Report”. Monaldi Archives for Chest Disease 93 (3). https://doi.org/10.4081/monaldi.2022.2388.
Copyright (c) 2022 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Hussein Soleimantabar, Sofia Sabouri, Leila Khedmat, Samira Salajeghe, Behzad Memari, Bahareh Heshmat Ghahderijani, Assessment of CT angiographic findings in comparison with echocardiography findings of chest among patients with aortic arch anomalies , Monaldi Archives for Chest Disease: Vol. 89 No. 3 (2019)
- Kamal Kant Sahu, Ajay Kumar Mishra, Kevin Martin, Iryana Chastain, COVID-19 and clinical mimics. Correct diagnosis is the key to appropriate therapy , Monaldi Archives for Chest Disease: Vol. 90 No. 2 (2020)
- Vasiliki Epameinondas Georgakopoulou, Dimitrios Mermigkis, Despoina Melemeni, Aikaterini Gkoufa, Christos Damaskos, Nikolaos Garmpis, Anna Garmpi, Nikolaos Trakas, Xanthi Tsiafaki, Cytomegalovirus pneumonia in an immunocompetent host with primary ciliary dyskinesia: A case report , Monaldi Archives for Chest Disease: Vol. 91 No. 3 (2021)
- Atefeh Mir, Khadijeh Kalan Farmanfarma, Hamid Salehiniya, Abolfazl Shakiba, Neda Mahdavifar, Laboratory and demographic findings among patients with coronavirus disease 2019: a review , Monaldi Archives for Chest Disease: Vol. 91 No. 4 (2021)
- Ugo Corrà, Fabiana Isabella Gambarin, Marco Gnemmi, Massimo Pistono, Exertional and nocturnal periodic breathing after successful cardiac transplantation. A case report , Monaldi Archives for Chest Disease: Vol. 91 No. 2 (2021)
- Vito Maurizio Parato, Sara Belleggia, Andrea Giovanni Parato, Umberto Ianni, Michela Molisana, Germana Gizzi, Simone D'Agostino, Melissa Dottori, Marco Di Eusanio, Multi-valve Libman-Sacks’s endocarditis-related multiple, massive and fatal systemic embolization. A case report and a review of diagnostic work-up , Monaldi Archives for Chest Disease: Early Access
- Joana Lourenço, Ana Paula Vaz, Rosa Anita Fernandes, Cristina Lopes, Ana Luísa Fernandes, Evaluation of patients’ satisfaction with domiciliary biological treatment in severe asthma: a Portuguese survey , Monaldi Archives for Chest Disease: Early Access
- Lorenzo Carriera, Sara Caporuscio, Marta Fantò, Alice D’Abramo, Genesio Puzio, Luca Triolo, Angelo Coppola, Combination treatment with monoclonal antibodies for the management of severe asthma and immune-mediated inflammatory diseases: a comprehensive review , Monaldi Archives for Chest Disease: Early Access
- Hiroaki Satoh, Yuika Sasatani, Pulmonary co-infection with Actinomyces odontolyticus and Mycobacterium kansashii , Monaldi Archives for Chest Disease: Vol. 92 No. 3 (2022)
- Shyam Kanhaiya Saroj, Tushti Bhardwaj, Non-pharmacological interventions for tobacco cessation: A systematic review of existing practices and their effectiveness , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
<< < 48 49 50 51 52 53 54 55 56 57 > >>
You may also start an advanced similarity search for this article.
