Intracavitary fibrinolysis directly under vision during medical thoracoscopy: a case report

Submitted: August 8, 2022
Accepted: October 12, 2022
Published: November 2, 2022
Abstract Views: 917
PDF: 180
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Medical thoracoscopy is a minimally invasive single-port endoscopic technique that allows for direct visualization of the pleural surface as well as diagnostic and therapeutic procedures. When fibrous adhesions are extensive, its utility is limited. In patients with malignant pleural effusion and loculated effusion, fibrinolytics have been used through chest drainage to break down septations to relieve breathlessness and to improve pleurodesis success We described the use of intrapleural fibrinolytics during a medical thoracoscopy to break the septations and perform pleural biopsies in a patient with multiloculated pleural effusion. To the best of our knowledge, no studies on this subject have been published in the literature, only case reports. We believe that direct instillation of fibrinolytics during medical thoracoscopy is safe and has the potential to increase both the therapeutic and diagnostic capacity of medical thoracoscopy and fibrinolysis.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Murthy V, Bessich JL. Medical thoracoscopy and its evolving role in the diagnosis and treatment of pleural disease. J Thorac Dis 2017;9:S1011-21. DOI: https://doi.org/10.21037/jtd.2017.06.37
Rahman NM, Ali NJ, Brown G, et al. Local anaesthetic thoracoscopy: British Thoracic Society Pleural Disease Guideline 2010. Thorax 2010;65:ii54-60. DOI: https://doi.org/10.1136/thx.2010.137018
Khemasuwan D, Sorensen J, Griffin DC. Predictive variables for failure in administration of intrapleural tissue plasminogen activator/deoxyribonuclease in patients with complicated parapneumonic effusions/empyema. Chest 2018;154:550-6. DOI: https://doi.org/10.1016/j.chest.2018.01.037
Banka R, Terrington D, Mishra EK. Management of septated malignant pleural effusions. Curr Pulmonol Rep 2018;7:1-5. DOI: https://doi.org/10.1007/s13665-018-0194-3
Thomas R, Piccolo F, Miller D, MacEachern PR, et al. Intrapleural fibrinolysis for the treatment of indwelling pleural catheter-related symptomatic loculations: A multicenter observational study. Chest 2015;148:746-51. DOI: https://doi.org/10.1378/chest.14-2401
Terashita S, Kawachi H, Horikawa S, et al. Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of malignant pleural mesothelioma with severe multiloculated pleural effusions. J Bronchology Interv Pulmonol 2019;26:e26-7. DOI: https://doi.org/10.1097/LBR.0000000000000576
Terashita S, Kawachi H, Tajiri T, et al. Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy. Respirol Case Rep 2019;8:e00498. DOI: https://doi.org/10.1002/rcr2.498

How to Cite

Stirpe, Emanuele, Floriana Bardaro, and Johanna Köhl. 2022. “Intracavitary Fibrinolysis Directly under Vision During Medical Thoracoscopy: A Case Report”. Monaldi Archives for Chest Disease 93 (3). https://doi.org/10.4081/monaldi.2022.2400.

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.