https://doi.org/10.4081/monaldi.2023.2527
RETRACTED: Prescription analysis emphasizing on medication adherence of antibiotics for lower respiratory tract infection
Submitted: January 16, 2023
Accepted: July 23, 2023
Published: August 7, 2023
Accepted: July 23, 2023
Abstract Views: 801
PDF_early view: 246
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Antibiotics are choice of drugs in patients with respiratory infections. Irrational use of antibiotics is an important public health issue faced on daily basis by the community and the individual. Keeping this in consideration, the current study investigates the prescription pattern of antibiotics in lower respiratory tract infection in general population.The objectives of the study include prescription pattern analysis of antibiotics for LRTIs in general population and to evaluate adherence to antibiotic treatment. This was a hospital based prospective observational study conducted between November 2021 to April 2022 in the department of general medicine and pediatrics. Compliance to various antibiotics was scrutinized by using MMAS 4 scale. Patient demographics, laboratory details, prescribed antibiotics, duration of hospital stay were gathered over a period of 6 months.A total of 200 patients were involved in the study, out of which 53% were males and 47% were females. A total of 2127 drugs were prescribed in 200 patients (10.6 drugs/prescription). Ceftriaxone was the most commonly used antibiotic followed by azithromycin and piperacillin/tazobactam. The most frequently diagnosed disease was Bronchopneumonia (41%) followed by A/E COPD (28%). Evaluation of medication adherence resulted in 58% high and 11% poor adherence. The number of antibiotics prescribed was found to be rational but prevalence of polypharmacy should be prevented. Medication adherence decreases as the frequency of antibiotic increases, so it is recommended to lower the frequency of drugs as possible to enhance the compliance.
Beg MA, Dutta SB, Bawa S, et al. Prescribing trends in respiratory tract infections in a tertiary care teaching hospital. Int J Res Med Sci 2017;5:2588-91.
DOI: https://doi.org/10.18203/2320-6012.ijrms20172452
Omairsohail Ahmed, Mohammed Abdul Ali, Omer Wasiq, et al. A study on prescribing trends in respiratory tract infections in a tertiary care hospital. Int J Res Hos Clin Pharm 2019;1:50-6.
DOI: https://doi.org/10.33974/ijrhcp.v1i2.55
Suwitha S, Suriya P, Senthilvelan, et al. A Study on prescribing pattern in lower respiratory tract infections among adults in a tertiary care teaching hospital. Pharma Innovation 2019; 8:169-74.
Priyanka E, Vineela R, Arshiya A, Alekya S. Analysis of the prescribing patterns of antibiotics in respiratory tract infections at department of medicine at a tertiary care hospital. Int J Pharm Sci 2015; 6:2963-67.
Satya Sai MK, Divya K, Devi G, Sharma S. A study on prescribing pattern of antibiotics in respiratory tract infections in a tertiary care center. Int J Sci Res 2015;6:4558-63.
Atif M, Azeem M, Sarwar M, et al. WHO/INRUD prescribing indicators and prescribing trends of antibiotics in the Accident and Emergency Department of Bahawal Victoria Hospital, Pakistan. Springerplus 2016;5:1928.
DOI: https://doi.org/10.1186/s40064-016-3615-1
Rosalia R, Essam Atta N, Gebreigziabher F, et al. A cross sectional survey on compliance to antibiotics in patients with respiratory tract infections in a tertiary hospital in Ajman, UAE. J Pharm Pract Community Med 2019;5:43-8.
DOI: https://doi.org/10.5530/jppcm.2019.2.11
Zabihi A, Qanbari Qalehsari M, Jafarian Amiri S, et al. A survey on medication adherence and its associated factors in antibiotic-takers following their discharge from hospital. Shiraz E Med J 2021;22:1-6.
DOI: https://doi.org/10.5812/semj.113782
Tan X, Patel I, Chang J. Review of the four item Morisky Medication Adherence Scale (MMAS-4) and eight item Morisky Medication Adherence Scale (MMAS-8). Inovv Pharma 2014;5:1-8.
DOI: https://doi.org/10.24926/iip.v5i3.347
Shafinaz, Joel JJ, Bhat VS, Er AR. Study on drug utilization pattern of antibiotics in respiratory tract infections. Res J Pharm Technol 2019;12:1189-92.
DOI: https://doi.org/10.5958/0974-360X.2019.00197.5
Ahmed N The Rate of Adherence to Antibiotics and Reasons for Non-adherence among the Public. J Pharm Res Int 2020;32:42-7.
DOI: https://doi.org/10.9734/jpri/2020/v32i730458
Panicker S, Chitra B. Drug utilization evaluation of antibiotics at a tertiary care hospital. Int J Pharm Pharm Res 2016;7:350-9.
Baby B, Haque I, Angalimol P T, et al. A study on prescribing pattern of antibiotics for respiratory tract infection in pediatric outpatient in a tertiary care hospital: a prospective observational study. Int J Pharm Sci Rev Res 2019;6:30-3.
MB H, MB R, Basavaraj B, E A. Prescribing pattern of antibiotics in lower respiratory tract infection among children aged less than 5 years. Indian J Pharm Pharmacol 2016;3:182-5.
Nirmal Kumar R, Selva P. Analysis of prescription pattern of antibiotics among patients with respiratory tract infections at a tertiary care hospital. Biomed Pharmacol J 2019;12:1595-602.
DOI: https://doi.org/10.13005/bpj/1790
Llor C, Hernández S, Bayona C, et al. A study of adherence to antibiotic treatment in ambulatory respiratory infections. Int J Infect Dis 2013;17:168-72.
DOI: https://doi.org/10.1016/j.ijid.2012.09.012
Mathew E, Koshy N, Telaprolu M, et al. Assessment of patient compliance with antibiotic treatment for lower respiratory tract infection in children. Pharma Innov 2019;8:746-52.
Ethics Approval
The study protocol was approved by the Institutional Ethical Committee of KLE College of Pharmacy Hubballi, A constituent unit of KLE Academy of Higher Education and Research, Belagavi, Karnataka, IndiaHow to Cite
Nyamagoud, Sanatkumar Bharamu, A H M Viswanatha Swamy, Anchu S P, Sonia S Gaitonde, Jaison M Johnson, and Vishwanath Hegadal. 2023. “RETRACTED: Prescription Analysis Emphasizing on Medication Adherence of Antibiotics for Lower Respiratory Tract Infection”. Monaldi Archives for Chest Disease, August. https://doi.org/10.4081/monaldi.2023.2527.
Copyright (c) 2023 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Muhammad Ijaz, Muhammad Jaffar Khan, Jawad Khan, . Usama, Association of clinical characteristics of patients presenting with influenza like illness or severe acute respiratory illness with development of acute respiratory distress syndrome , Monaldi Archives for Chest Disease: Vol. 87 No. 1 (2017)
- Michele Vitacca, Luca Barbano, Daniele Colombo, Olivia Leoni, Enrico Guffanti, Prevalence and variability of use of home mechanical ventilators, positive airway pressure and oxygen devices in the Lombardy region, Italy , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- Massimiliano Polastri, Lara Pisani, Andrea Dell'Amore, Stefano Nava, Revolving door respiratory patients: A rehabilitative perspective , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- Claudio F. Donner, Sandro Amaducci, Elena Bacci, Sandra Baldacci, Maria L. Bartoli, Gianfranco M. Beghi, Alida Benfante, Sara Brighindi, Lucio Casali, Daniela Castiglia, Mario Cazzola, Alessandro Celi, Silvana Cianchetti, Giorgio Colombo, Claudia Crimi, Federico L. Dente, Giuseppe Di Maria, Annalisa Di Maria, Manuela Latorre, Federico Lavorini, Sara Maio, Claudia Mannini, Riccardo Messina, Pier Luigi Paggiaro, Patrizia Pignatti, David Price, Nicola Scichilone, Marzia Simoni, Antonio Spanevello, Martina Stagno d’Alcontres, Shawna Tan, Roberto Torchio, Giovanni Viegi, Dina Visca, Emiel F.M. Wouters, Shaylynn Yu Hui Xin, Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD , Monaldi Archives for Chest Disease: Vol. 88 No. 1 (2018)
- A.G. Corsico, S. Villani, M.C. Zoia, R. Niniano, E. Ansaldo, G. Cervio, P.M. Quaresima, E. Gatto, E. Crippa, A. Marinoni, A. Foresi, E. Pozzi, I. Cerveri, Chronic productive cough in young adults is very often due to chronic rhino-sinusitis , Monaldi Archives for Chest Disease: Vol. 67 No. 2 (2007): Pulmonary series
- S. Bertini, M. Picariello, M. Gorini, T. Renda, A. Augustynen, G. Villella, G. Misuri, N.M. Maluccio, R. Ginanni, D. Tozzi, A. Corrado, Telemonitoring in chronic ventilatory failure: a new model of survellaince, a pilot study , Monaldi Archives for Chest Disease: Vol. 77 No. 2 (2012): Pulmonary series
- L. Barbano, E. Bertella, M. Vitacca, Episodic medical home interventions in severe bedridden Chronic Respiratory Failure patients: a 4 year retrospective study , Monaldi Archives for Chest Disease: Vol. 71 No. 3 (2009): Pulmonary series
- Francesco Barillà , Concetta Torromeo, Riccardo Iorio, Luigina Porco, Vincenzo Paravati, Carlo Gaudio, Antiplatelet therapy in elderly patients with acute coronary syndrome: Between scientific evidence and future perspectives , Monaldi Archives for Chest Disease: Vol. 88 No. 2 (2018)
- A. Chetta, M. Aiello, P. Tzani, D. Olivieri, Assessment and monitoring of ventilatory function and cough efficacy in patients with amyotrophic lateral sclerosis , Monaldi Archives for Chest Disease: Vol. 67 No. 1 (2007): Pulmonary series
- The Rehabilitation Complexity Scale for respiratory patients Italian network, The ability of the Rehabilitation Complexity Scale (RCS) to capture disability in respiratory patients admitted for in-hospital rehabilitation , Monaldi Archives for Chest Disease: Early Access
You may also start an advanced similarity search for this article.
