https://doi.org/10.4081/monaldi.2023.2655

Aortic root diameter, main pulmonary artery diameter/aortic root diameter and pericardial fat volume as predictors of occlusive coronary artery disease

Vol. 94 No. 2 (2024)
Submitted: July 24, 2023
Accepted: August 16, 2023
Published: September 13, 2023
Aortic root, pericardial fat, coronary artery disease, pulmonary artery, multi-detector computed tomography
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Authors

Abdulameer A. Al-Mosawi
Radiology Department, Medicine College, University of Kufa, Najaf, Iraq.
Hussein Nafakhi
husseinaf.alnaffakh@uokufa.edu.iq
https://orcid.org/0000-0002-0238-0460
Internal Medicine Department, Medicine College, University of Kufa, Najaf, Iraq.
Hadeel K. Hameed
https://orcid.org/0009-0006-9039-0082
Radiology Department, Medicine College, University of Kufa, Najaf, Iraq.

The clinical relevance of aortic root diameter (ARD), main pulmonary artery diameter (MPAd), or pericardial fat volume (PFV) in the assessment of coronary artery disease (CAD) is largely unknown. We aimed to assess the relationship of PFV, ARD, MPAd, and MPAd/ARD ratio with occlusive CAD (stenosis >50%).This cross-sectional study included patients who had chest pain suggestive of CAD and underwent a 64-multislice multi-detector computed tomography angiography exam to exclude occlusive CAD presence. A total of 145 patients were enrolled in this study. The mean age was 54±10 years, and 51% were males. The mean PFV, ARD, MPAd, and MPAd/ARD ratio in all patients were 155 cm3, 29.9 mm, 23.4 mm, and 0.8, respectively. On univariate analysis, PFV [odds ratio (OR) (confidence interval, CI)=1.1 (1.01-1.3), p<0.01], ARD [OR (CI)=1.2 (1.1-1.4), p<0.01], and MPAd/ARD ratio [OR (CI)= 0.2 (0.1-0.5), p=0.02] showed significant association with occlusive CAD presence. After adjusting for cardiac risk factors, only PFV [OR (CI)=1.1 (1.02-1.3), p<0.01], but not ARD [OR (CI)=0.9(0.3-2), p=0.85] or MPAd/ARD ratio [OR (CI)=0.1(0.1-2), p=0.69], was independently associated with occlusive CAD. In conclusion, increased PFV, but not ARD or MPAd/ARD ratio, showed a significant and independent association with occlusive CAD presence in patients with chest pain suggestive of CAD.

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Ethics Approval

Approval of this study was provided by the IRB of the Medicine College, University of Kufa, Najaf (Iraq) with approval number (MEC-012021).

How to Cite

Al-Mosawi, Abdulameer A., Hussein Nafakhi, and Hadeel K. Hameed. 2023. “Aortic Root Diameter, Main Pulmonary Artery Diameter Aortic Root Diameter and Pericardial Fat Volume As Predictors of Occlusive Coronary Artery Disease”. Monaldi Archives for Chest Disease 94 (2). https://doi.org/10.4081/monaldi.2023.2655.
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