https://doi.org/10.4081/monaldi.2023.2663
Family long QT syndrome type 2 associated with KCNH2 gene mutation: aborted sudden cardiac death
Submitted: June 13, 2023
Accepted: August 28, 2023
Published: September 13, 2023
Accepted: August 28, 2023
Abstract Views: 629
PDF_early view: 403
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
A complete screening was performed in a family after one of its members presented with a sudden cardiac death event. A genetical analysis revealed a mutation which led to a long QT syndrome.
Cox KO, Wang BX. Long QT syndrome type 2: mechanism-based therapies. Future Cardiol 2021;17:1453-63.
DOI: https://doi.org/10.2217/fca-2020-0234
Schwartz PJ, Crotti L, Insolia R. Long-QT syndrome: from genetics to management. Circ Arrhythm Electrophysiol 2012;5:868-77.
DOI: https://doi.org/10.1161/CIRCEP.111.962019
Neira V, Enriquez A, Simpson C, et al. Update on long QT syndrome. J Cardiovasc Electrophysiol 2019;30:3068-78.
DOI: https://doi.org/10.1111/jce.14227
Vandenberg JI, Perry MD, Perrin MJ, et al. hERG K(+) channels: structure, function, and clinical significance. Physiol Rev 2012;92:1393-478.
DOI: https://doi.org/10.1152/physrev.00036.2011
Schwartz PJ, Priori SG, Spazzolini C, et al. Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation 2001;103:89-95.
DOI: https://doi.org/10.1161/01.CIR.103.1.89
Shah SR, Park K, Alweis R. Long QT syndrome: a comprehensive review of the literature and current evidence. Curr Probl Cardiol 2019;44:92-106.
DOI: https://doi.org/10.1016/j.cpcardiol.2018.04.002
Schwartz PJ, Moss AJ, Vincent GM, et al. Diagnostic criteria for the long QT syndrome. An update. Circulation 1993;88:782-4.
DOI: https://doi.org/10.1161/01.CIR.88.2.782
Schwartz PJ, Crotti L. QTc behavior during exercise and genetic testing for the long-QT syndrome. Circulation 2011;124:2181-4.
DOI: https://doi.org/10.1161/CIRCULATIONAHA.111.062182
Viskin S, Postema PG, Bhuiyan ZA, et al. The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome. J Am Coll Cardiol 2010;55:1955-61.
DOI: https://doi.org/10.1016/j.jacc.2009.12.015
Zeppenfeld K, Tfelt-Hansen J, de Riva M, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J 2022;43:3997-4126.
DOI: https://doi.org/10.1093/eurheartj/ehac699
How to Cite
Elizalde Uribe, Iván Alejandro, Diego Mendoza Lagos, Aldo César Cazares Diazleal, Elias Noel Andrade Cuellar, and Gerardo Payró Ramírez. 2023. “Family Long QT Syndrome Type 2 Associated With <em>KCNH2< em> Gene Mutation: Aborted Sudden Cardiac Death”. Monaldi Archives for Chest Disease, September. https://doi.org/10.4081/monaldi.2023.2663.
Copyright (c) 2023 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Roberto Valle, Nadia Aspromonte, Emanuele Carbonieri, Giorgio De Michele, Giuseppe Di Tano, Prospero Giovinazzo, Roberta Cioè, Tiziana Di Giacomo, Loredano Milani, Federica Noventa, Mario Chiatto, BNP-guided therapy optimizes the timing of discharge and the medium term risk stratification in patients admitted for congestive heart failure , Monaldi Archives for Chest Disease: Vol. 68 No. 3 (2007): Cardiac series
- Gennaro Ismeno, Antonio Falco, Francesco Paolo Tritto, Antonio d’Angelo, Francesco Longobardi, Girolamo Damiani, Joseph Marmo, Rosario Gregorio, Luigi Piazza, The use of “LAST†operation in high risk patient , Monaldi Archives for Chest Disease: Vol. 66 No. 1 (2006): Cardiac series
- Marco Ambrosetti, Simona Sarzi Braga, Franco Giada, Roberto F.E. Pedretti, Exercise-based cardiac rehabilitation in cardiac resynchronization therapy recipients: A primer for practicing clinicians , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- Gian Francesco Mureddu, Current multivariate risk scores in patients undergoing non-cardiac surgery , Monaldi Archives for Chest Disease: Vol. 87 No. 2 (2017)
- Ombretta Omodeo, Elena Fiabane, Ines Giorgi, Claudia Grandis, Alessandra Gualco, Monica Ceresa, Psychological needs and mental health in women aged ≥ 65 years after cardiac surgery: an exploratory study , Monaldi Archives for Chest Disease: Vol. 80 No. 1 (2013): Cardiac series
- T. Kinnunen, O. Säynäjäkangas, T. Keistinen, Features of hospitalisations for acute exacerbation of COPD resulting in death , Monaldi Archives for Chest Disease: Vol. 67 No. 1 (2007): Pulmonary series
- Achille Pulcino, Chiara Sordelli, Gennaro Ismeno, Francesco Paolo Tritto, Paolo Golino, Luigi Piazza, A case of quadricuspid aortic valve characterized by echocardiography and magnetic resonance imaging , Monaldi Archives for Chest Disease: Vol. 76 No. 3 (2011): Cardiac series
- Francesco Vetta, Gabriella Locorotondo, Giampaolo Vetta, Maria Mignano, Sonia Bracchitta, Prognostic impact of frailty in elderly cardiac surgery patients , Monaldi Archives for Chest Disease: Vol. 87 No. 2 (2017)
- Francesco Fattirolli, Alessandra Pratesi, Cardiovascular prevention and rehabilitation in the elderly: evidence for cardiac rehabilitation after myocardial infarction or chronic heart failure , Monaldi Archives for Chest Disease: Vol. 84 No. 1-2 (2015): Cardiac series
- Francesco Giallauria, Marco Gentile, Paolo Chiodini, Franco Berrino, Amalia Mattiello, Luigi Maresca, Alessandra Vitelli, Maria Mancini, Alessandra Grieco, Angelo Russo, Rosa Lucci, Giorgio Torella, Salvatore Panico, Carlo Vigorito, Exercise training reduces high mobility group box-1 protein levels in women with breast cancer: findings from the DIANA-5 study , Monaldi Archives for Chest Disease: Vol. 82 No. 2 (2014): Cardiac series
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
