https://doi.org/10.4081/monaldi.2023.2729
Multi-valve Libman-Sacks’s endocarditis-related multiple, massive and fatal systemic embolization. A case report and a review of diagnostic work-up
Submitted: July 23, 2023
Accepted: September 3, 2023
Published: October 9, 2023
Accepted: September 3, 2023
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
We reported a case of non-bacterial thrombotic endocarditis (NBTE) in a 37-year-old woman who presented with signs and symptoms of cardio-embolic cerebral stroke caused by a prothrombotic state due to underlying advanced uterine cancer. Multimodal imaging, including 3D-ecocardiography, as well as laboratory and cultural tests, were critical in making the diagnosis. After starting anticoagulation therapy with low molecular weight heparin (LMWH), the patient underwent surgical aortic valve replacement due to worsening aortic valve function, initial left ventricle enlargement, increasing dimensions, and mobility of vegetations. Unfortunately, vegetations relapsed on the aortic valve bio-prosthesis as well as the mitral leaflets, resulting in a final picture of multi-valve NBTE. The fatal outcome was due to a massive multiple limb embolism, which resulted in leg amputations and septical complications. Starting with the case, we present a brief overview of the pathology's presentation, treatment, management, and prognosis, as well as the diagnostic work-up.
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How to Cite
Parato, Vito Maurizio, Sara Belleggia, Andrea Giovanni Parato, Umberto Ianni, Michela Molisana, Germana Gizzi, Simone D’Agostino, Melissa Dottori, and Marco Di Eusanio. 2023. “Multi-Valve Libman-Sacks’s Endocarditis-Related Multiple, Massive and Fatal Systemic Embolization. A Case Report and a Review of Diagnostic Work-up”. Monaldi Archives for Chest Disease, October. https://doi.org/10.4081/monaldi.2023.2729.
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