https://doi.org/10.4081/monaldi.2024.2852
Tailored treatment for tuberculosis in transgender individuals: a call for a patient-centered approach from a large Italian cohort
Published: January 11, 2024
Abstract Views: 358
PDF_EARLY VIEW: 223
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Tuberculosis (TB) diagnosis and management in special populations remain challenging. Data about TB and transgender individuals is scarce, and strategies aimed at reducing the TB burden in this at-risk group are needed. We conducted an observational monocentric study from a national reference center for TB, including transgender individuals with active TB in a low-TB burden country (Italy), over 34 years (1990-2023). Sixty-six transgender males and two transgender females (median age 30 years, interquartile range 26-38 years, 65 migrants) were included. Most patients (38/66, 57.6%) lived in poor social conditions. 65.2% (43/66) of patients were people living with HIV. Multidrug- and rifampicin-resistant tuberculosis and isoniazid-resistant TB were diagnosed in five (7.6%) and three (4.5%) patients, respectively. The overall treatment success rate was 72.7% (48/66 patients), with differences observed according to social conditions. Our study highlights the need for a tailored approach to increase treatment success in this at-risk population.
World Health Organization. Global tuberculosis report 2022. Available from: https://iris.who.int/bitstream/handle/10665/363752/9789240061729-eng.pdf?sequence=1.
Matucci T, Riccardi N, Occhineri S, et al. Treatment of latent tuberculosis infection in incarcerated people: a systematic review. Clin Microbiol Infect 2023;29:714-21.
DOI: https://doi.org/10.1016/j.cmi.2023.02.016
Riccardi N, Antonello RM, Ferrarese M, et al. Tuberculosis in migrants: epidemiology, resistance and outcome in Milan, Italy. Infect Dis 2023;55:543-50.
DOI: https://doi.org/10.1080/23744235.2023.2217912
Shah SA, Qayyum S, Baig S, et al. Results of community-based TB and HIV screening among transgender women and male sex workers in Pakistan. PLOS Glob Public Health 2023;3:e0000913.
DOI: https://doi.org/10.1371/journal.pgph.0000913
Pareek M, Greenaway C, Noori T, et al. The impact of migration on tuberculosis epidemiology and control in high-income countries: a review. BMC Med 2016;14:48.
DOI: https://doi.org/10.1186/s12916-016-0595-5
Commission of the European Communities. Commission decision of 28 April 2008 amending decision 2002/253/EC laying down case definitions for reporting communicable diseases to the Community network under decision no 2119/98/EC of the European Parliament and of the Council. In: Official Journal, L159/46, 18/06/2008.
Getahun H, Matteelli A, Chaisson RE, Raviglione M. Latent mycobacterium tuberculosis infection. N Engl J Med 2015;372:2127-35.
DOI: https://doi.org/10.1056/NEJMra1405427
World Health Organization. WHO consolidated guidelines on tuberculosis. Module 4: treatment - drug-resistant tuberculosis treatment, 2022 update. Available from: https://iris.who.int/bitstream/handle/10665/365308/9789240063129-eng.pdf?sequence=1.
Canetti D, Antonello RM, Saderi L, et al. Impact of SARS-CoV-2 infection on tuberculosis outcome and follow-up in Italy during the first COVID-19 pandemic wave: a nationwide online survey. Infez Med 2022;30:418-26.
DOI: https://doi.org/10.53854/liim-3003-10
Morrison H, Perrin F, Dedicoat M, et al. Impact of COVID-19 on NHS tuberculosis services: Results of a UK-wide survey. J Infect 2023;87:59-61.
DOI: https://doi.org/10.1016/j.jinf.2023.04.004
Ethics Approval
The study received ethical approval n. 578–112,018 from the ethical committee of ASST Niguarda Ca′ Granda in Milan (Italy) and it was conducted in agreement with the Declaration of Helsinki (1964) and its later amendments.How to Cite
Riccardi, Niccolò, Roberta Maria Antonello, Maurizio Ferrarese, Alice Repossi, Laura Saderi, Giovanni Fumagalli, Giorgio Besozzi, Giovanni Sotgiu, and Luigi Codecasa. 2024. “Tailored Treatment for Tuberculosis in Transgender Individuals: A Call for a Patient-Centered Approach from a Large Italian Cohort”. Monaldi Archives for Chest Disease, January. https://doi.org/10.4081/monaldi.2024.2852.
Copyright (c) 2024 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Vinay V, Saraansh Bansal, Pallavi Purwar, Ravindra Kumar Dewan, Paras Verma, Shalini Mullick, Mallika Dixit, B Rama Phanindra , Kanishk Siddhartha, Thoracic follicular dendritic cell sarcoma - an outlandish presentation of a rare tumour with review of literature , Monaldi Archives for Chest Disease: Vol. 93 No. 2 (2023)
- S. Contini, G. Raimondi, P. Graziano, C. Saltini, M. Bocchino, Difficult diagnosis of Infliximab-related miliary tuberculosis , Monaldi Archives for Chest Disease: Vol. 61 No. 2 (2004): Pulmonary series
- M. Bugiani, S. Bonora, A. Carosso, P. Piccioni, M. Cavallero, A. Mondo, V. Ghisetti, The effect of antituberculosis treatment on interferon-γ release assay results , Monaldi Archives for Chest Disease: Vol. 75 No. 4 (2011): Pulmonary series
- Maddalena Modica, Roberta Carabalona, Rosa Spezzaferri, Monica Tavanelli, A. Torri, Vittorino Ripamonti, Paolo Castiglioni, Renata De Maria, Maurizio Ferratini, Psychological profiles derived by cluster analysis of Minnesota Multiphasic Personality Inventory and long term clinical outcome after coronary artery by pass grafting , Monaldi Archives for Chest Disease: Vol. 78 No. 1 (2012): Cardiac series
- Elena Sogaro, Francesca Schininà , Costanza Burgisser, Francesco Orso, Rachele Pallante, Teresa Aloi, Duccio Vanni, Adolfo Pazzagli, Francesco Fattirolli, Type D personality impairs Quality of Life, coping and short-term psychological outcome in patients attending an outpatient intensive program of cardiac rehabilitation , Monaldi Archives for Chest Disease: Vol. 74 No. 4 (2010): Cardiac series
- Halil Yanardag, Cuneyt Tetikkurt, Muammer Bilir, Erkan Yılmaz, Association of HLA antigens with the clinical course of sarcoidosis and familial disease , Monaldi Archives for Chest Disease: Vol. 87 No. 3 (2017)
- F. Scafa, C.M. Minelli, R. Fonte, G.L. Rosso, M.I. Cappelli, S.M. Candura, Silicotuberculosis in the elderly: report of two cases , Monaldi Archives for Chest Disease: Vol. 61 No. 4 (2004): Pulmonary series
- Valeriu Plesca, Ana Ciobanu, Yuliia Sereda, Andrei Dadu, Do catastrophic costs impact treatment outcomes in people with rifampicin-resistant tuberculosis in the Republic of Moldova? , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Lilit Gevorgyan, Ruzanna Grigoryan, Kostyantyn Dumchev, Kristina Akopyan, Anush Khachatryan, Eduard Kabasakalyan, Trdat Grigoryan, Marina Safaryan, Vardan Avagyan, Sayohat Hasanova, Alberto Matteelli, Factors associated with unfavourable treatment outcomes in people with HIV-associated tuberculosis in Armenia, 2015 to 2019 , Monaldi Archives for Chest Disease: Vol. 91 No. 1 (2021)
- Morgan Daniel, Charles Ricordel, Aurélien Lorleac'h, James Norwood, Bertrand Richard De Latour, Simon Rouzé, Jean-Philippe Verhoye, The illusion of a chest wall tumor: a case-report of sternal tuberculosis , Monaldi Archives for Chest Disease: Vol. 92 No. 4 (2022)
<< < 1 2 3 4 5 6 7 8 9 10 > >>
You may also start an advanced similarity search for this article.
